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Slide 1: Antibiotics that Require Frequent Monitoring (Aminoglycosides)
Slide 2: Drugs Amikacin Troughs 5 mcg/ml Peaks 35 mcg/ml
Slide 4: Drugs Gentamicin Troughs 2 mcg/ml Peaks 10 mcg/ml
Slide 6: Drugs Kanamycin Troughs 5 mcg/ml Peaks 35 mcg/ml
Slide 8: Drugs Neomycin Troughs 2 mcg/ml Peaks 16 mcg/ml
Slide 10: Drugs Streptomycin Troughs Varies Peaks 25 mcg/ml
Slide 12: Drugs Tobramycin Troughs 2 mcg/ml Peaks 20 mcg/ml
Slide 14: Drugs Vancomycin Troughs 5-10 mcg/ml Peaks 25 mcg/ml
Slide 16: • Aminoglycosides must be monitored carefully for side effects including ototoxicity (vestibular and cochlear), nephrotoxicity, neurotoxicity, and hypersensitivity reactions. Monitor patients for tinnitus, vertigo, hearing loss, rash, dizziness, or difficulty urinating.
Slide 17: • Renal lab tests that must be monitored include urinalysis, specific gravity, BUN, creatinine, and creatinine clearance.
Slide 18: • Liver lab tests that must be monitored include , AST (SGOT), ALT (SGPT), serum alkaline phosphatase, bilirubin, creatinien, and LDH concentrations.
Slide 19: • Trough# levels are referred to as the minimum drug concentration that proceeds the administration of a single dose of medication. Trough levels should be drawn just prior to the next dose
Slide 20: • Peak* levels are referred to as the maximum drug concentration that follows the administration of a single dose of medication. Peak levels should be drawn 1 hour after IM injections and 30 minutes after a 30-minute IV infusion is completed.
Slide 21: “Nurses Informations” http://nursesinformations.blogspot.com
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