National Campaign

My India,  Addiction Free India

DRUG DEPENDENC
A NEUROLOGICAL

 

Medical Wing
(Rajayoga Education & R...
What is addiction? 

Alcohol addiction
Tobacco addiction
Drug addiction

Sex addiction
Gambling addiction
Food addiction
S...
Definition of addiction

“Addiction is a state of periodic or chronic intoxication
produced by repeated consumption of dru...
Definition of addiction contd. ... 

- Substance dependence,  or addiction,  as
defined by the DSM-IV,  is indicated by
th...
Definition of addiction contd. ... 

0 Tolerance:  Does the patient tend to need more of the drug over
time to get the sam...
Definition of addiction cont. ... 

* Substance abuse,  as defined by the DSM-IV, 
involves a maladaptive pattern of subst...
Tolerance-e. g..  heroin,  The need to increase a
fix to get the high they used to get. 

it That feels great =    _ 

~ T...
Withdrawl Symptoms

- Can include shakes,  irritability,  moodiness <3:
nausea. 

- These are not uncommon when use of a
p...
Mood modification. 

° What a rush

 

- I was buzzing

 

- It makes me feel relaxed

- Addicts bring about mood chan es....
Salience -An extract from Tony. 

t If I wash 't ac tua/ /y gambling I was
spending the rest of my time working
out c/ e v...
i °
{'0 A‘  Flfl I CT

I
ms WI

 

6 Addicts often have a great deal of
conflict with others around them, 
causing misery. ...
Two decades of
Neurobiological Researches
have
brought us a new understanding of
Drug Abuse and Addiction, 
their complexi...
We know that despite
their many differences, 
virtually all abused substances
enhance
Dopamine (neurotransmitter) activity...
Dopamine Pathways

     
 

striatum

frontal .  ' hiPP0C3mP“S
cortex
I

substantia

Functions
°reWard (motivation) Seroto...
Dopamine Transporter Loss After
Heavy Methamphetamine Use
(PET analysis)

 

Comparison Subject METH Abuser

Ssourccc:  Ve...
© 2013 Medical Wing of Rajayoga Education & Research Foundation.  All rights reserved.
Drug Dependence - A Neurologic Perspective
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Drug Dependence - A Neurologic Perspective

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Drug Dependence - A Neurologic Perspective by Medical Wing of Rajayoga Education & Research Foundation, a sister concern of Brahma Kumaris

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Drug Dependence - A Neurologic Perspective

  1. 1. National Campaign My India, Addiction Free India DRUG DEPENDENC A NEUROLOGICAL Medical Wing (Rajayoga Education & Research Foundation) PRAJAPITA BRAHMA KUMARIS ISHWARIYA VISHWA VIDYALAYA Ever Healthy Hospital, Shantivan Complex Abu Road, Rajasthan © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  2. 2. What is addiction? Alcohol addiction Tobacco addiction Drug addiction Sex addiction Gambling addiction Food addiction Shopping addiction Internet addiction VVVVVVVVV © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved. Cell phone addiction . ?«-< ,
  3. 3. Definition of addiction “Addiction is a state of periodic or chronic intoxication produced by repeated consumption of drug, natural or synthetic" (World Health Organisation) There is a growing feeling that the definitions need to encompass addictions that do not necessarily require the user to ingest a substance © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  4. 4. Definition of addiction contd. ... - Substance dependence, or addiction, as defined by the DSM-IV, is indicated by the presence of three or more of the criteria listed below in the last 12 months. Note that all but the first two criteria reflect some form of loss of control over the use of or effects of the drug. © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  5. 5. Definition of addiction contd. ... 0 Tolerance: Does the patient tend to need more of the drug over time to get the same effect? 0 Withdrawal symptoms: Does the patient experience withdrawal symptoms when he or she does not use the drug? t Continued use of drug despite harm: Is the patient experiencing physical or psychological harm from the drug? * Loss of control: Does the patient take the drug in larger amounts, or for longer than planned? * Attempts to cut down: Has the patient made a conscious, but unsuccessful, effort to reduce his or her drug use? - Salience: Does the patient spend significant time obtaining or thinking about the drug, or recovering from its effects? t Reduced involvement: Has the patient given up or reduced his or her involvement in social, occupational or recreational activities due to the drug? © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  6. 6. Definition of addiction cont. ... * Substance abuse, as defined by the DSM-IV, involves a maladaptive pattern of substance use resulting in significant negative physical, social, interpersonal or legal consequences. Unlike substance dependence, the criteria for abuse do not include tolerance, withdrawal or a pattern of compulsive or uncontrolled use. © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  7. 7. Tolerance-e. g.. heroin, The need to increase a fix to get the high they used to get. it That feels great = _ ~ That's not enough anymore = Now I need X2 to feel Good. ~ That feels better = © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  8. 8. Withdrawl Symptoms - Can include shakes, irritability, moodiness <3: nausea. - These are not uncommon when use of a pCll"'l'lCUlCll" S'l'l lTUlCll’l'l' (not necessarily / ngested—cou/ d be refraining from a said behaviour) It / s be/ /eved they are a result of chemical changes . ... ... . . .but what if you have not ingested anything andget these side effects? Could it be the refraining from the beha v/ our / tse/ f causing the symp toms? © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  9. 9. Mood modification. ° What a rush - I was buzzing - It makes me feel relaxed - Addicts bring about mood chan es. Relaxation, escapism are some of the words used to describe the feeling from engaging in the addictive behaviour. © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  10. 10. Salience -An extract from Tony. t If I wash 't ac tua/ /y gambling I was spending the rest of my time working out c/ e ver / itt/ e schemes to obtain money to feed my habit. These two activities / itera/ /y took up a/ / my time" t This indicates to tal neaccu atian. Re verse salience is when the addictive behaviour becomes the most important thing in the persons / ife. © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  11. 11. i ° {'0 A‘ Flfl I CT I ms WI 6 Addicts often have a great deal of conflict with others around them, causing misery. ° The conflict is sometimes within themselves too. - Continuing to use the said behaviour relieves the conflict, it is used as a sort of coping strategy. © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  12. 12. Two decades of Neurobiological Researches have brought us a new understanding of Drug Abuse and Addiction, their complexity and their solutions © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  13. 13. We know that despite their many differences, virtually all abused substances enhance Dopamine (neurotransmitter) activity (particularly related to pleasure, motor and cognitive function. 0 Other pathways also involved! 13 Medical Wing of Ra a o a Education & Research Foundation All ri hts reserved
  14. 14. Dopamine Pathways striatum frontal . ' hiPP0C3mP“S cortex I substantia Functions °reWard (motivation) Serotonin Pathways -pleasure, euphoria _ -motor function I]-l‘“nct10nS (fine tuning) 'm00d °compulsion -memory -perserveration processing -decision making _ S1 e ep
  15. 15. Dopamine Transporter Loss After Heavy Methamphetamine Use (PET analysis) Comparison Subject METH Abuser Ssourccc: Vellrew, Ni-D-. at all, Am JJ-. Irswiiiatrrw, 1i$%(@. ),, [$19.37/’77'%%Q. ,l%11-. © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
  16. 16. © 2013 Medical Wing of Rajayoga Education & Research Foundation. All rights reserved.
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