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  • 346 © 2001 Schattauer GmbH What is Bioinformatics? A Proposed Definition and Overview of the Field N. M. Luscombe, D. Greenbaum, M. Gerstein Department of Molecular Biophysics and Biochemistry Yale University, New Haven, USA Summary 1. Introduction related to this new field has been surging, and now comprise almost 2% of the Background: The recent flood of data from genome annual total of papers in PubMed. sequences and functional genomics has given rise to Biological data are being produced at a This unexpected union between the two new field, bioinformatics, which combines elements of biology and co