2012 COMPANY PROFILEubio is a young, vibrant venture developing innovative solutions in medical, veterinary and food diagnostics. We leverage the latest and best technologiesfrom the fields of electronics, information technology, and biotechnology to create products and solutions that take hi-tech diagnostics to the mass-market.ubio’s vision is Affordable, Accurate, Accessible Diagnostics for All. ubio’s mission is to develop high-quality diagnostic products and make them accessible to everyone at low cost, while creating value for its customers, employees, investors and partners. ubios product portfolio includes low-cost rapid tests for human, veterinary and food diagnostics that make diagnostics affordable and accessible to patients, farmers and small industries without any capital investment. We have also developed a new generation biochip for clinical diagnostics market that will provide high quality test assays at significantly lower price points. Headquartered at Cochin, Kerala, India, ubio brings together key scientific and engineering talent with experience in the cutting-edge of biotechnology, information technology and electronics. Our technology leaders have proven expertise in product development and management, and have made major contributions to software and biotechnology industries. ubio was established in 2008 and the R&D laboratory and Manufacturing Facilities are located at Kinfra Biotechnology Park, in Kerala. The GMP and ISO 13485 certified manufacturing facility is approved by Indian Drug Regulatory authorities for the manufacture of IVDs. The R&D facility of ubio is approved by Department of Scientific and Industrial Research, Government of India. GMP CERTIFIED ubio Business Profile Veterinary and Food Medical IVD Tests Contract Manufacture Contract Research Tests Companion Animal Lateral-flow tests Diagnostic tests Infectious Diseases development Tests •ELISA, Lateral-flow, LAT, PCR etc. ELISA kits Cancer and Cardiac Livestock Recombinant Tests Diagnostics protein and Latex Agglutination antibody tests development Drug of Abuse and Antibiotic and toxin Raw Materials and Fertility Products residues PCR tests uncut sheets
2012 HUMAN DIAGNOSTICS The sensit tests are one-step Immuno-chromatographic assays for the detection of antigen or antibodies in human Blood, serum, plasma or other body fluids.These rapid tests are inexpensive, disposable, membrane based RAPIDassays that provides visual evidence of the presence of an analyte in ONE STEPclinical samples. The test uses colloidal gold conjugated antigen or POINT –OF-CAREantibodies for visualisation of the results. The test kit consists of aplastic cassettes containing a membrane strip. Thebase substrate of the test is usually a nitrocellulosemembrane in which the test and control Positiveantigen/antibodies are printed at specific locations. Aconjugate pad, a glass fibre sheet is attached to thisstrip which contains dried gold conjugates. A samplepad and absorbent pad are attached each ends, one act as sample Negativewick and the other as sink. The results are available within When the sample is added to the sample pad, it will move 20 minutes. Suitable for testing in lowtowards the gold conjugate pad, re-hydrating the gold conjugate resource setting.and allowing the interaction of sample analyte with the conjugate. Portable, no need of equipment. Results are comparable to ELISAThe complex of gold conjugate and analyte then moves onto the or other gold standards.membrane strip and migrate towards the capture proteins printed Stable at room Temperature upto 2 yearson Test Line. The binding of gold conjugate complex will produce anintense red line at the test line. A second line is also formed at thecontrol line region by the excess gold conjugate.
2012ubio SENSIT Rapid TestsTropical Diseases Malaria ProductsFilariasis Antibody Test Malaria Antigen TestLateral flow Immunoassay for anti Wuchereria bancrofti These tests detect Plasmodium falciparum HRP antigen and/orand Brugia malayi antibodies in human Blood, serum or Plasmodium vivax/Pan LDH antigen in Whole blood.plasma. Malaria Pf HRP/Pan LDH Antigen testLeishmaniasis Antibody Malaria Pf HRP/Pv LDH Antigen testOne step Immuno qualitative detection of antibodies to Malaria Pf HRP Antigen testmembers of L. donovani complex in human serum. Malaria Pan LDH Antigen testAvailable as strips and cassette (whole blood).Typhoid IgM Malaria Pv LDH Antigen testLateral flow assay for the specific detection of SalmonellaTyphi specific IgM antibodies in Human Blood, serum or Malaria Antibody TestPlasma One step immuno-chromatographic assay for detection ofBrucella IgG Pv/Pf MSP and CSP specific antibodies of all isotypes (IgA, IgGLateral flow assay for detection of IgG response of and IgM) in Human blood, serum or PlasmaBrucella abortus, Brucella melitensis and brucella suisinfection in human. Enteric infectionsLeptospira IgM Rota-Adeno Antigen testIgM lateral flow assay for Human Leptospirosis. The test is Rapid immuno-chromatographic assay for detection of Rotaable to detect all serovars of Leptospira that causes and Adeno virus antigens in human stool in acute gastroleptospirosis in humans. enteritis cases.Human TB antigen tests H Pylori Antibody H.pylori test is a rapid test for the qualitative detection ofMPT 64 Antigen test antibodies of all isotypes (IgG, IgM, IgA, etc.) specificOne step Immuno-chromatographic assy for the detection to Helicobacter pylori in human serum, plasma or whole bloodof MPT 64 Tb antigen in culture fluids and solid cultures. H Pylori Antigen TestTB LAM Test H.pylori Ag test is a rapid test for the qualitative detectionMycobacterium tuberculosis and bovis specific of Helicobacter pylori antigen in human fecal specimen.Lipoarabinomannan antigen detection test for culturefluids. (also can be used for sputum testing) Fertility Hormones Contract manufacturing and Loan licensing LH test options. Home ovulation test for detection of Luteinising Hormone in Tests are available is 1 test, 10 tests, 25, 30 and human urine.(25mIU/ml) 50 tests OEM options hCG Home urine pregnancy test for detection of human chorionic Products are available as uncut sheets Gonadotropins in Human urine. (10mIU/ml). Available as Card and Strips
2012 VETERINARY DIAGNOSTICSAnimal Health Diagnostics ubio quickVET Rapid TestsOne step Immuno-chromatographic Bovine Tests Canine Rapid Testsassays Bovine TB Rapid Test Bovine Brucella Rapid test Canine Parvovirus Antigen TestAccurate Bovine TB-Brucella Combo Test Canine Distemper Virus antigen Test Bovine FMD NSP Rapid test* Canine Corona Virus antigen testHigh sensitive and good correlation Bovine Anaplasma Ab Rapid test. CPV-CCV Combo testwith other test method FMD antigen Rapid test.* Canine Adeno virus antigen test Rota Virus Test Canine Ehrlichia Rapid test Rabies virus antigen test Canine Lyme Antibody testAnywhere Bovine Viral Diarrhoea antigen test Canine Leptospira IgM test Bovine pregnancy Rapid Test Canine Leishmania Antibody test - Laboratory, Farm, Clinic, Home: Bovine Theilaria Rapid Test* Canine Brucella antibody testNo equipment needed Bovine Babesia rapid test.* Ag/Ab Rabies Antibody test Bovine-Haemo-Protozoan Panel*Simple Infectious Bovine Rhino-Tracheitis Ab test - One Step after collection a sample Bovine leukaemia Virus Ag Test Bovine Leukaemia Test Ab testFast Neospora Antibody test - Reliable Result within 10 min. Swine Tests Avian Swine Brucella IBD antigen test Swine FMD* NDV antigen testImmediate Echinococcus antibody test Marek’s Disease Antigen test Porcine Corona Virus antigen test Infectious Bronchitis Antigen test- Treatment and Avian Influenza antigen Test PRRSV antigen TestManagement(vaccination, Classical Swine Fever Ag Test Avian antibody Tests:quarantine) after identifying the TGEV antigen test. Avian Leukosis Virus Antigencause Pseodo-rabies(Ajeskey’s disease) Antigen test Rabies products FelineSelf Rabies antigen tests Feline Toxoplasma Antibody test Rabies FITC conjugate FeLV antigen Test - Self testing by Pet owner or Rabies ELISA kit FIV antibody testFarmer themselves FIV-FeLV Combo Feline Parvo Rapid TestLow cost Ovine Tests Fish/ Aquatic Brucella ovis Rapid test WSSV lateral Flow* - Time, Labor, Money saving Aeromonas caviae Stenotrophomonas maltophilia *under development * coming soon Positive Negative
2012 DRUG OF ABUSE* A drug test is a technical analysis of a biological specimen – for example urine, hair, blood, sweat, or oral fluid / saliva – to determine the presence or absence of specified parent drugs or their metabolites. Major uses of drug testing are to detect the presence of performance enhancing steroids in sport or for drugs prohibited by laws, such as cannabis, cocaine and heroin. The drug abuse may lead to health problems, Social problems, Physical dependence or psychological addiction Product Target Compound Cut-Off levels(ng/ml) AMP Amphetamine 1000 ng/ml BAR Barbital 300 ng/ml BZO Benzodiazepine 300 ng/ml BUP Buprenorphine 10 ng/ml COC Cocaine 300 ng/ml KET Ketamine 300 ng/ml MDMA Methylenedioxymethamphetamine 1000 mg/ml MTD Methadone 300 ng/ml MET Methamphetamine 1000 ng/ml MOR Morphine 300 ng/ml OXY Oxycodone 300 ng/ml PCP Phencyclidine 25 ng/ml PPX Propoxyphene 300 ng/ml TCA Tricyclic Antidepressants 1000 ng/ml THC Tetrahydrocannabinol 50 ng/ml DOA-Multi Test Combination 2 or more tests Human Blood stain Tests* One step Immuno-chromatographic test to detect haemoglobin residues in human blood and Blood stains Semen test*FORENSIC One step Immuno-chromatographic test to detect Prostate Specific Antigen presence in human semen or semen stains Note: these Products are available only on OEM and on Bulk orders.
2012 RAW MATERIALS & FOOD DIAGNOSTIC DIAGNOSTICS REAGENTSLATERAL FLOW RAW MATERIALSUncut Sheets(Master Sheets)Uncut sheets of all the rapid tests are available. The standard size is 300X60mm. custom sizing andmembrane type is possible for a minimum order of 20 sheets.Colloidal goldColloidal gold for various application like manufacture of rapid IVD kits, Cat. No SpecImmuno electron microscopy application. UCG10000 10 litersAvailable in sizes from 5nm, 10nm, 15, 20, 25, 30 and 40nms. UCG1000 1000mlSupplied unconjugated with or without preservatives UCG100 100ml UCG10 10mlColloidal silverColloidal silver for various application like manufacture of Lateral Cat. No SpecFlow Assays UCS10000 10 liters UCS1000 1000ml UCS100 100ml UCS10 10mlColloidal gold ConjugatesColloidal gold conjugated with antibodies, usually at a rate of 10-30microgram per ml of gold. Available invarious ODs.Anti-Human IgG40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No SpecSupplied in Tris-Buffer with sodium azide preservative. UCG0101 1mg UCG0102 5mgAnti-Rabbit IgG40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No SpecSupplied in Tris-Buffer with sodium azide preservative. UCG0201 1mg UCG0202 5mgAnti-Mouse IgG40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No SpecSupplied in Tris-Buffer with sodium azide preservative. UCG0301 1mg UCG0302 5mgAnti-Goat IgG40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No SpecSupplied in Tris-Buffer with sodium azide preservative. UCG0401 1mg UCG0502 5mgAnti-Bovine IgG40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No SpecSupplied in Tris-Buffer with sodium azide preservative. UCG0501 1mg UCG0602 5mgAnti-BSA IgG
201240nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No SpecSupplied in Tris-Buffer with sodium azide preservative. UCG0601 1mg UCG0602 5mgProtein A40nm colloidal gold conjugated to purified recombinant protein A(30µg/ml of Cat. No Specgold). Supplied in Tris-Buffer with sodium azide preservative. UCG0701 10mg UCG0702 100mgProtein G40nm colloidal gold conjugated to purified recombinant protein G(30µg/ml of Cat. No Specgold). Supplied in Tris-Buffer with sodium azide preservative. UCG0801 1mg UCG0902 10mg UCG0903 100mgProtein A/G40nm colloidal gold conjugated to purified recombinant protein A/G(30µg/ml of Cat. Nogold). Supplied in Tris-Buffer with sodium azide preservative. UCG1001 10mg UCG1002 100mgNano-particlesCdSe quantum dot Particle These are suitable forCdS Quantum dot Particle quantum dot basedZnO Quantum dot Particle diagnostics.Fe3O4 Ferro-liquid /FePt Ferro-liquidMagnetic beads suitable for magnetic bead separationsELISA ReagentsTMB: SolubleTMB - This aqueous non-hazardous liquid substrate for peroxidase consists of Tetramethylbenzidine Cat. No Spec(TMB) plus dilute hydrogen peroxide in a single-reagent stabilized form. The reagent has beenspecifically formulated for measuring peroxidase in ELISA systems which is stable for long-term UER-CT-01 125mlstorage providing sensitivity greater than OPD. This reagent is available as a single component, UER-CT-02 500mlready-to-use reagent. When used in conjunction with our proprietary TMB Stop Buffer (TSB), the UER-CT-03 1000mlresulting color product will not fade or darken for several hours. Our TMB products have built a UER-CT-04 20Litersreputation for robust performance, unparalleled stability and next to zero lot-to-lot variation. EachTMB formulation can be specifically engineered to meet the needs of your specific assayTMB MembraneThis liquid substrate for peroxidase consists of tetramethylbenzidine (TMB) plus dilute hydrogen Cat. No Specperoxide in a single-reagent stabilized form. The reagent has been specifically formulated formeasuring peroxidase in EIA systems. This reagent is stable for long-term storage, and provides UER-CTP-01 125mlsensitivity equal to, or greater than, that of other commercially available chromogens. UER-CTP-02 500ml UER-CTP-03 1000ml UER-CTP-04 10LitersDAB One-Component Solution (3,3-Diaminobenzidine)his reagent produces a crisp, clean, very intense stain that is free of unwanted background. When in Cat. No Specthe presence of peroxidase, DAB produces a brown precipitate that is insoluble in alcohol. Stainedslides may be mounted in any commercially available mounting media. This product is stable UER-DAB-01 125mlfor 2-3 months. UER-DAB 02 500ml UER-DAB-03 1000mlTMB Stop bufferubios Stop Buffer (TSB) offers a unique combination of acid that produces a more stable stopped Cat. No Specreaction product than other formulations of H2SO4 or HCL. Stopped reactions show increasedabsorbance values of approximately two-fold over unstopped reactions with minimal drift for up to UER-SBT-01 125mlsix hours depending on various conditions. UER-SBT-02 500ml UER-SBT-03 1000ml UER-SBT-04 20LitersBCIP-NBT: soluble5-Bromo-4-Chloro-3-Indolyl Phosphate/nitroblue Tetrazolium (BCIP/NBT) Solution. Is a widely used Cat. No Specchromogen for immunohistochemical and in-situ staining. This reagent is available as a singlecomponent, ready to-use reagent. When in the presence of the Alkaline-Phosphatase enzyme, UER-NBT-01 125ml
2012BCIP/NBT produces a purple precipitate that is soluble in alcohol. UER-NBT-02 500ml UER-NBT-03 1000ml UER-NBT-04 20LitersELISA Coat StabiliserCoating Stabilizer has been developed specifically for the stabilization of adsorbed or immobilized Cat. No Specproteins on microwell plates/strips. Coating Stabilizer maintains the conformation and activity of theantibody or protein antigen portion of the dried immunoassay components. Product is filtered at 0.2 UER-CS-01 125mlmicrons. UER-CS-02 500mlContents: Aqueous, protein-containing stabilizer and blocking solution in phosphate buffer for dried UER-CS-03 1000mlprotein components in immunoassays. Preservative: 0.02% Bromonitrodioxane, 0.02% 2-Methyl-4-isothiazolin-3-one. pH 7.2 - 7.7ELISA HRP stabiliser: Phosphate BufferedThis product has been developed to significantly increase the shelf life of diluted peroxidase labeledproteins. Stability is increased at room temperature storage conditions in addition to 2- 8centigrade. This product is subjected to 0.45 micron filtration, and contains no mercury or azide. Cat. No SpecThis formulation insures consistently high levels of activity for both the enzyme and the antibody UER-HS-01 500mlfollowing long-term storage at final-use dilution. HRP Stabilizer greatly improves the signal to noise UER-HS-02 1000mlratios which increases the immunoassay sensitivity and offers cleaner assays.This product has beenchemically engineered to increase conjugate stability providing the customer a longer shelf life,resistance to various shipping conditions & storage temperaturesand improved day to day assay precision.Alk-Phos Stabilizing DiluentThis reagent is formulated specifically for Alkaline Phosphatase conjugates. The product insuresconsistently high levels of activity for both the enzyme and the antibody following longterm storage Cat. No Specat final dilution. This product has been chemically engineered to increase conjugate stabilityproviding the customer a longer shelf life, resistance to various shipping conditions and storage UER-AS-01 500mltemperatures. Alk-Phos Stabilizing Diluent is filtered at 0.2 um and reinforced with a non-mercury or UER-AS-02 1000mlazide-free preservative. Inquire about custom vialing, labeling, kit assembly and drop shipping.ELISA Developers KIT: HRP/AP BasedComplete "Do it Yourself" ELISA system. Contents:The first ELISA system designed to deliver superior results to each and every research project, Blocking Buffer, HRP/APregardless of the level of technician expertise. Everything that is required to obtain outstanding Stabilizing Diluent, Binding Buffer,results is included in one convenient package. Easy ELISA has been specifically developed to create Coating Stabilizer, TMB Solublean environment in which the researcher can be assured of consistent results with each project. All of Reagent, TMB Stop Buffer, Samplethe reagents contained in Easy ELISA are stable enough to ship at ambient temperature. Diluent, Wash Buffer (10X PBS) Cat. No Spec UER-1K 1 kitCustom ELISA ReagentsAll of the ELISA products are available in bulk quantities, including custom lot sizes up to 5000 liters. Ubio specializes in custommanufacturing, vialing, labelling and packaging. E mail us for a quote
2012 ubios state-of-the-art manufacturing facility at Kalamassery, Cochin, India can manufacture Contract conventional diagnostic kits in addition to our patented biochip devices. We offer contract manufacture of all kinds of Rapid and ELISA kits on OEM terms. Manufacture Being a start-up, ubio is nimble and provides short turn-around times for manufacture and a very responsive customer-care. We can manufacture test kits even in small batches, which makes us the right partner for firms who want to test their brand in the market before installing a complete manufacturing facility. ubio is the right manufacturing For further details on our OEM service write partner for you, especially if you to: email@example.com ubio can manufacture and supply complete test kits need: with all components including plastic containers, droppers, printed packaging, outer cartons etc. which Variable-volume manufacture leaves you time and money to concentrate on product marketing Quick introduction of new product into the market without initial capital investment Protection for your investment against market fluctuations, ubio has full capability for the development of Immunoassays, Molecular diagnostics and Microarray obsolescence, and competition chips for various applications. We can take up the product development even from the development of Quick scale-up to peak demandAssay Development at ubio basic raw materials like recombinant protein/peptides without capital investment or monoclonal antibodies. Low turnaround time Validated Technology Platforms, Our platform technologies include. Product development using Lateral flow assays technologies already commercialised by ubio. Flow through Assays Particle Conjugation Technologies Contract Enzyme Linked Immunosorbant Assays Stable Products, and flexibility in optimisation. Line probe and Dot probe assays Low Density Microarrays. Assay Clinical validation in actual PCR-lateral Flows. samples. 100% confidentiality. Bead Based Assays. Fluorescence based assays. Development Quantitative and semi-quantitative Assays. Scaling up and pilot manufacturing Small molecules assays facility Option for further contract manufacture Full Technology Transfer For Further Details on our Research Continuous support from ubio Services, Write to: firstname.lastname@example.org Team.
2012 ORDERING INFORMATION Contact Information ubio Biotechnology Systems Pvt Ltd, XII-111-E/F, Technology Incubation Centre KINFRA Hi-Tech Park, Kalamassery Cochin, Kerala, India 683503 Tel. No: +91-484-2532966 E mail: email@example.com Web: www.ubio.inPricingThe prices will be quoted either in INR or USD. Quantity discounts are available for Bulk orders.CancellationThe orders can be cancelled within 2 days after placing the purchase order.Payment TermsAll orders are prepaid unless prior credit arrangements have been made with us. All orders are FOB, Cochinand freight charges and Insurance have to be borne by the customer. Special shipping charges can benegotiated with our shipping agent for bulk orders. The payment can be made by Wire Transfer, Letter ofCredit or Bank Draft.Our Bank Details are as follows. For customers in India For Overseas Customers BANK NAME AND ADDRESS : STATE BANK OF INDIA, M. BANK NAME AND ADDRESS: STANDARD G. ROAD BRANCH, ERNAKULAM, KERALA CHARTERED BANK, ERNAKULAM BRANCH, ACCOUNT NAME: UBIO BIOTECHNOLOGY SYSTEMS PVT. RAVIPURAM, ERNAKULAM, KERALA, INDIA. LTD. BENEFICIARY NAME: UBIO BIOTECHNOLOGY IFSC CODE: SBIN0003539 SYSTEMS PVT LTD ACCOUNT NO: 30641422205 SWIFT CODE: SCBLINBBCON BENEFICIARY ADDRESS: XII-111-E/F, TECHNOLOGY ACCOUNT NO.: 43405060909 INCUBATION CENTRE, KINFRA HI-TECH PARK, BENEFICIARY ADDRESS: XII-111-E/F, KALAMASSERY, COCHIN, KERALA, INDIA 683503 TECHNOLOGY INCUBATION CENTRE, KINFRA HI- TECH PARK, KALAMASSERY, COCHIN, KERALA, INDIA 683503ShippingThe shipments are made on FCA basis unless otherwise specified. Custom Packaging is possible on request.Returned Goods PolicyNo Return shall be accepted without prior approval from ubio.
2012 ubio Biotechnology Systems Pvt LtdXII-111-E/F, Technology Incubation Centre, KINFRA Hi-Tech Park, Kalamassery, Cochin, Kerala, India , 683503Ph:,+91-484-2532966/+91-9744122269, E mail: firstname.lastname@example.org , www.ubio.in