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Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
Using side effects of medicines to identify drug targets
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Using side effects of medicines to identify drug targets

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CeMM, Vienna (2008-06-12) …

CeMM, Vienna (2008-06-12)
Paper: http://www.ncbi.nlm.nih.gov/pubmed/18621671

Published in: Technology, Health & Medicine
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  • 1. Using side effects of medicines to identify drug targets Michael Kuhn Peer Bork lab, EMBL Heidelberg mkuhn@embl.de
  • 2. Drugs and their targets Side effects Prediction of drug targets
  • 3. Drugs • only consider organic small molecules • no antibodies, peptides, ions • ~750 drugs with side effects • ~600 drugs with targets
  • 4. Targets • most drugs bind to proteins
  • 5. Targets • most drugs bind to proteins • few exceptions, e.g.: • alkylating antineoplastic agents (which modify DNA) • contrast agents for X-ray • saline solution

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