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Atherosclerosis
 

Atherosclerosis

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    Atherosclerosis Atherosclerosis Presentation Transcript

    • ATHEROSCLEROSIS WEEK 4 BIOCHEMISTRY
    • WHAT IS ATHEROSCLEROSIS?
      • Atherosclerosis - is a disease in which plaque builds up inside your arteries. Arteries are blood vessels that carry oxygen-rich blood to your heart and other parts of your body.
      • Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows your arteries, limiting the flow of oxygen-rich blood to your organs and other parts of your body. This can lead to serious problems, including heart attack, stroke, or even death.
    • ATHEROSCLEROSIS
    • ETIOLOGY
      • IDIOPATHIC
      • However, studies show that atherosclerosis is a slow, complex disease that may start in childhood. It develops faster as you age.
    • ETIOLOGY
      • Atherosclerosis may start when certain factors damage the inner layers of the arteries. These factors include:
      • Smoking
      • High amounts of certain fats and cholesterol in the blood
      • High blood pressure
      • High amounts of sugar in the blood due to insulin resistance or diabetes
    • RISK FACTORS
      • Male gender- lack LDL-lowering effect of estrogen
      • Family history/genetics
      • Cigarette smoking- carbon monoxide-induced hypoxic injury to endothelial cells
      • Age
      • Lack of Physical Activity
      • Unhealthy Diet
    • S/SX
      • Atherosclerosis usually doesn't cause signs and symptoms until it severely narrows or totally blocks an artery. Many people don't know they have the disease until they have a medical emergency, such as a heart attack or stroke.
      • Coronary artery- myocardial infarction (heart attack)
      • Cerebral artery- stroke
      • Renal vessels- renovascular HPN
      • Blood vessels of the extremities- gangrene
    • HOW IS ATHEROSCLEROSIS TREATED?
      • Treatments for atherosclerosis may include lifestyle changes, medicines, and medical procedures or surgery.
      • The goals of treatment include:
      • Relieving symptoms
      • Reducing risk factors in an effort to slow or stop the buildup of plaque
      • Lowering the risk of blood clots forming
      • Widening or bypassing plaque-clogged arteries
      • Preventing atherosclerosis-related diseases