Chronic gastritis, ulcers & risk of stomach cancer
Increased concentration of Pancreatic enzymes
Decreased volume of enzyme secretion
Decreased insulin production –
Bleeding Pancreas of an Alcoholic, he’s now dead!
Pyloric Valve- Spasms in the presence of large amounts of ethanol Small Intestine- Majority of Ethanol absorbed here Damages Mucosal Cells, Villi, and Microvilli Decreases absorption of nutrients and vitamins Increases Triglyceral and Cholesterol production
Decreased amounts of Bile Secretion
Decreased water and vitamin absorption
Alcohol can even cause skin problems such as acne and splotchy skin.
BLOOD CHANGES RBC Decreased Production-Anemia WBC Decreased production Decreased response time more infections Increased risk for STD’s/HIV
Decreased clotting time
More bumps and bruises
Inhibits Vasopressin release
Decreases thyroid hormones,
Luteinizing hormone, and others
Males Damages or kills Leydig Cells Increases feminine characteristics Decreased sexual drive, reproductive failure, impotence Females Early Menopause Premenstrual discomfort Increased menstrual Flows Infertility
Skeletal Muscle Di srupts internal structure of muscle Cramps, pain, weakness Alcoholic Myopathy
FOETAL ALCOHOL SYNDROME
Most common preventable cause of adverse CNS development
Greatly reduced intelligence
5 or more drinks in a sitting for men
4 or more drinks in a sitting for women
Dangers of Binge Drinking
Unintentional injuries (e.g. car crash, falls, burns, drowning).
Intentional injuries (e.g. firearm injuries, sexual assault, domestic violence).
STD’s and/or Unintended pregnancy.
High blood pressure, stroke, and other cardiovascular diseases.
B. Acute alcoholic intoxication
Hypotension, gastritis, hypoglycemia, collapse, respiratory depression, coma & death
METHANOL FORMALDEHYDE FORMIC ACID Aldehyde DH TOXIC EFFECT DUE TO FORMIC ACID
MANIFESTATIONS OF TOXICITY
Headache,vertigo,severe abdominal pain,vomiting,hypotension,delirium, acidosis & coma
Affinity for optic n retinal damage blindness(15ml)
Correction of acidosis-IV sodium bicarbonate
Maintain BP & ventilation
Drinking before age 21 is ILLEGAL!!! Don’t gamble with your future!
It Kills and Badly Injures
TOO MANY YOUNG LIVES ARE LOST EACH YEAR
After a nasty break up she got drunk and went for a drive, with a BAC of .19, missed a turn, flipped and rolled the car more than 5 times. Fifteen surgeries later she is disfigured and blind with permanent brain damage, luckily she did not hurt or kill anyone else. Meet Denise Wagoner