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Mik Black NZ Society of Oncologists 2010

Mik Black NZ Society of Oncologists 2010

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Mik Black NZ Society of Oncologists 2010 Presentation Transcript

  • 1. Collaborative initiatives that are changing the face of cancer research  Mik Black Department of Biochemistry University of Otago
  • 2. The good old days: sharing data
  • 3. The good old days: sharing data
  • 4. Oncomine: adding value
  • 5. http://www.broadinstitute.org/cmap/
  • 6. Nature Reviews Cancer, 2007: 7(1) 54-60
  • 7. Nature (2008) vol. 455 (7216) pp. 1061-8 http://tcga.cancer.gov/
  • 8. http://www.sanger.ac.uk/genetics/CGP/
  • 9. http://www.icgc.org/
  • 10. http://www.icgc.org/
  • 11. https://cabig.nci.nih.gov/ http://cabig.cancer.gov/
  • 12. http://cabig.cancer.gov/caBIGstory/vision/ http://cabig.cancer.gov/caBIGstory/mission/
  • 13. http://cagrid.org/
  • 14. BeSTGRID: Broadband-enabled Science and Technology GRID http://www.bestgrid.org
  • 15. BeSTGRID: Broadband-enabled Science and Technology GRID Nick Jones Director, BeSTGRID Associate Director eResearch Centre for eResearch http://www.bestgrid.org The University of Auckland n.jones@auckland.ac.nz
  • 16. eResearch landscape
  • 17. A few BeSTGRID activities… http://sakai.bestgrid.org http://www.geneious.com/karen http://www.cellml.org http://biomirror.org.nz Coming soon… + BLAST
  • 18. Putting the bits together… •  Large “meta-cohort” of public breast cancer samples: –  2116 patients: molecular, clinical, and treatment information –  Collaboration with Assoc Prof Lance Miller (Wake Forest), Dr Heather Cunliffe (TGen), Assoc Prof Cris Print (Auckland). •  Goal: molecular markers for personalized prediction: prognosis and response to treatment.
  • 19. Acknowledgements University of Otago The University of Auckland Marcus Davy Nick Jones Thomas Allen Mark Gahegan Sarah Song Yuriy Halytskyy Anthony Reeve Cristin Print Parry Guilford Daniel Hurley John McCall Christoff Knapp Tony Merriman University of Canterbury Translational Genomics (TGen) Vladimir Mencl Heather Cunliffe Wake Forest University Lance Miller