Goat Slideshow

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  • PAVL DOES NOT DO ANY OF THESE TESTS
  • NOTE TIME REQUIRED FOR INFECTED ANIMALS TO TEST POSITIVE FOR EACH TYPE OF TEST. THIS EXAMPLE IS BASED ON BRUCELLA INFECTION IN BOVINES.
  • Goat Slideshow

    1. 1. Pan American Veterinary Laboratories Hutto, TX Privately Owned Robert Glass Established 1993 Lab Services for Goats Sheep Horses Cattle Dogs Swine > 500,000 test performed
    2. 2. Purpose of Laboratory Testing Diagnosis of Disease Test and Treat Prevention of Disease Test and Don’t Buy Eradication of Disease Test and Cull
    3. 3. Laboratory Diagnostics Major Organ Function Heart/Liver/Kidney Blood Chemistries Glucose Organ Specific Enzymes/Proteins Hematological Complete Blood Count(CBC) White Blood Cells Red Blood Cells Hemoglobin Hormone Levels Parasitology
    4. 4. Infectious Diseases Bacteria Corynebacterium pseudotuberculosis/Caseous Lymphadenitis Mycobacterium paratuberculosis/Johne’s Disease Brucella sp. Rickettsia Coxiella burnetii/Q Fever Virus Caprine Arthritis Encephalitis Parasite Toxoplasmosis Neospora caninum
    5. 5. Infectious Disease Diagnosis Infecting Agent Isolation/Identification Bacteria Culture and ID Fungi Culture and ID Virus Culture/ID of Genetic material Pros Definitive Results Cons Slow (days to weeks) Fresh and viable sample required False Negative results Expense
    6. 6. Infectious Disease Diagnosis Disease Specific Antibody Detection Infection induces immune response to fight the infection. Part of this response is the production of antibodies that specifically attach to and attack the infecting organism. Serological lab test are designed to identify these antibodies as indicators of infection. Pros Fast lab time 2-3 hours Accurate Inexpensive Blood Sample Cons May detect antibodies from past infections or other exposure.
    7. 7. Serological Assay Techniques Agglutination Antigen Antibody complexes which are visible to the human eye Precipitation Antigen Antibody complexes which fall out of solution Complement Fixation Antigen antibody reaction assay which results in cell lyses Enzyme Linked ImmunoSorbant Assay ELISA
    8. 8. Antigen Coated Wells Patient Serum Added Enzyme Labeled Anti IgG Added Color Development
    9. 9. Caprine Arthritis Encephalitis Retro virus (similar to HIV, FIV, EIA) Transmission infected animal’s blood cells Milk Blood Saliva Semen Symptoms Arthritis form: swollen knees hard udder decreased milk production shortened productive life span Encephalitis form: Paralysis and death Treatment None Eradication strategy: Test and Cull
    10. 10. Swollen Knees In CAE Positive Goat
    11. 11. Arthritis in CAE Positive Goat
    12. 12. Hard Udder in CAE Positive Goat
    13. 13. Encephalitis in CAE Positive Goat
    14. 14. Caseous Lymphadenitis Corynebacterium pseudotuberculosis Transmission Draining fluid/exudate from abscesses enter via: Oral intake (licking abscess) Breaks in the skin Symptoms Subcutaneous abscesses Internal abscesses Treatment Lance/Drain/Disinfect Inject with Formalin
    15. 15. CL Abscess
    16. 16. CL abscesses
    17. 17. CL abscess in Lung of Goat
    18. 18. Johne’s Disease Mycobacterium paratuberculosis Infection of the lining of the Intestinal tract leading to chronic inflammation and loss of ability to absorb nutrients Transmission Oral intake of infected feces Symptoms Moderate to fast loss of body condition with good appetite Diarrhea Treatment None Eradication Strategy Test and Cull
    19. 19. Johne’s Disease
    20. 20. Johne’s Disease
    21. 21. Zoonotic Diseases Diseases of animals that infect and harm Humans Q fever Rickettsia Coxiella burnettii Transmitted by birthing fluids of infected animals Symptoms Goats Humans Late term Abortions Rash and flu like symptoms Weak kids occasionally fatal, vegetative cardiac valve destruction Treatment: Various antibiotics including Tetracycline Toxoplasmosis Parasite Toxoplasma gondii Transmitted in milk and feces of infected animals Symptoms Goats Humans None Severe birth defects Treatment: Various antibiotics including Tetracycline
    22. 22. Holding goat for blood Collection
    23. 23. One person blood collection
    24. 24. One person blood collection
    25. 25. One person blood collection

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