Mannich Reaction
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Mannich Reaction

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Mannich Reaction Mannich Reaction Presentation Transcript

  • Mannich Reaction
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  • Nucleophilic Nitrogen Electrophilic Nitrogen
  • Substitution by Nucleophilic Nitrogen at Saturated Carbon
    • Treatment of RX with NH 3 gives a mixture of primary, secondary, tertiary and quarternary ammonium salts
    • Reaction of primary amine with primary alkylhalide gives secondary amine but reaction of primary amine with tertiary alkylhalide gives an elimination product
  • Addition of Nucleophilic Nitrogen to Unsaturated Carbon Reactions with Aldehydes and Ketones
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  • Reactions of Electrophilic Nitrogen
  • Nitration
  • Synthesis of Amino Acids Via Hell-Volhard Zelensky Reaction
  • Via Gabriel Procedure Via Nitrosation
  • Via Strecker Method
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