Mannich Reaction

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Mannich Reaction

  1. 1. Mannich Reaction
  2. 8. Nucleophilic Nitrogen Electrophilic Nitrogen
  3. 9. Substitution by Nucleophilic Nitrogen at Saturated Carbon <ul><li>Treatment of RX with NH 3 gives a mixture of primary, secondary, tertiary and quarternary ammonium salts </li></ul><ul><li>Reaction of primary amine with primary alkylhalide gives secondary amine but reaction of primary amine with tertiary alkylhalide gives an elimination product </li></ul>
  4. 10. Addition of Nucleophilic Nitrogen to Unsaturated Carbon Reactions with Aldehydes and Ketones
  5. 12. Reactions of Electrophilic Nitrogen
  6. 13. Nitration
  7. 14. Synthesis of Amino Acids Via Hell-Volhard Zelensky Reaction
  8. 15. Via Gabriel Procedure Via Nitrosation
  9. 16. Via Strecker Method

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