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Describe - Gene Control
 

Describe - Gene Control

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positive control, negative control, repressor protein, transcription factor initiation, action of the operator, RNA polymerase

positive control, negative control, repressor protein, transcription factor initiation, action of the operator, RNA polymerase

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    Describe - Gene Control Describe - Gene Control Presentation Transcript

    • Describe: gene control b.stev
    • BACTERIA: control which genes are expressed according to their requirements:
      • enzymes needed for chemical processes
      • proteins for renewal of cellular structures
      • defence monitoring of the environment
      • use of different components for replication
      • digestive requirements for the environment
      • control of timing and evolutionary change
      • TWO TYPES:
      • Positive control
      • Negative control
      (Wikipedia, 2008)
    • bacteria need to make specific enzymes to utilise lactose as a nutrient lactose binds to the repressor protein & prevents it from attaching to the DNA, thus allowing transcription to occur POSITIVE CONTROL: repressor protein attachment to the operator is prevented via chemical interaction: ie: presence of lactose (sugar) in the environment (Campbell N. A, Reece J. B, 2005)
    • when the REPRESSOR PROTEIN binds to the OPERATOR it prevents transcription regulatory gene operator structural genes promoter TRANSCRIPTION FACTOR OPERON RNA polymerase direction of transcription = lactose binds , allows transcription to occur
    • prevents RNA polymerase movement over the DNA strand’s structural genes that hold certain sequences for the protein(s) to be made NEGATIVE CONTROL:
      • prevents the process of transcription
      repressor protein is made that attaches to the operator on the transcription factor ie: tryptophan (amino acid), bacteria produce this though when enough has been made: regulatory gene produces the repressor protein that attaches without hindrance to the operator
    • the REPRESSOR PROTEIN binds to OPERATOR & prevents transcription regulatory gene operator structural genes promoter TRANSCRIPTION FACTOR (1) OPERON RNA polymerase direction of transcription
    • RNA polymerase can not move over the DNA strand: prevents transcription regulatory gene operator structural genes promoter TRANSCRIPTION FACTOR (2) - negative control RNA polymerase direction of transcription
    • Bibliography Campbell N. A, Reece J. B. (2005). Biology (7th ed.) . San Francisco: Benjamin Cummings Pommerville J.C. (2004). Alcamo’s – Fundamentals of Microbiology (7 th ed.). Massachusetts: Jones and Bartlett. Wikipedia. (2008). Gene expression – wikipedia, the free encyclopedia . Retrieved October 23, 2008, from http:www. en.wikipedia. org/wiki/ Gene _ expression - 49k -