Importance of Vitamin D In Orthopedic Patients
<ul><li>OSTEOPOROSIS   </li></ul><ul><li>is highly prevalent, affecting approximately   </li></ul><ul><li>one-third of wom...
<ul><li>OSTEOPOROSIS   </li></ul><ul><li>is the major cause of  FRACTURES   </li></ul>1992;7:1005-10
<ul><li>40% OF WOMEN   and 13% of men aged 50 years and older will sustain an   </li></ul><ul><li>OSTEOPOROTIC FRACTURE   ...
<ul><li>FRACTURES  have a profound impact on  QUALITY OF LIFE .  </li></ul><ul><li>Approximately  20%-25%  of women over a...
<ul><li>Both vertebral and hip fractures are associated with excess mortality. For instance, approximately  20% OF HIP FRA...
<ul><li>Patients being treated for  OSTEOPOROSIS  should be adequately supplemented with calcium and  VITAMIN D  to maximi...
<ul><li>Studies have also demonstrated a correlation between   </li></ul><ul><li>LOW SERUM VITAMIN D   </li></ul><ul><li>&...
<ul><li>Studies have also demonstrated a correlation between   </li></ul><ul><li>LOW SERUM VITAMIN D   </li></ul><ul><li>&...
<ul><li>Studies have also demonstrated a correlation between   </li></ul><ul><li>LOW SERUM VITAMIN D   </li></ul><ul><li>&...
<ul><li>VITAMIN D RECEPTORS  (VDRs) are known to be present in muscle tissue.  </li></ul>2001 Jan;33(1):19-24.  The Histoc...
<ul><li>Studies have also demonstrated a correlation between   </li></ul><ul><li>LOW SERUM VITAMIN D   </li></ul><ul><li>&...
<ul><li>Studies have also demonstrated a correlation between   </li></ul><ul><li>LOW SERUM VITAMIN D   </li></ul><ul><li>&...
<ul><li>Studies have also demonstrated a correlation between   </li></ul><ul><li>LOW SERUM VITAMIN D   </li></ul><ul><li>&...
<ul><li>Studies have also demonstrated a correlation between   </li></ul><ul><li>LOW SERUM VITAMIN D   </li></ul><ul><li>&...
<ul><li>Lower concentrations of 25(OH)D are associated with significant  BACK PAIN  in older women  </li></ul>2008 May;56(...
<ul><li>Vitamin D deficiency is now recognized as a  PANDEMIC  </li></ul>2008 Apr;87(4):1080S-6S.
<ul><li>VITAMIN D  Reduced the  </li></ul><ul><li>RISK OF FALLS  by More Than  20%  Among Elderly Populations </li></ul>20...
<ul><li>100 000 IU   VITAMIN D 3   every 4 months was safe and effective in decreasing the incidence of  </li></ul><ul><li...
<ul><li>Repletion of  VITAMIN D  and at the Time of Fracture May Reduce Future Fracture Risk and  FACILITATE   </li></ul><...
<ul><li>A single high dose of  VITAMIN D3  stimulated  </li></ul><ul><li>FRACTURE HEALING </li></ul>1997;116(1-2):37-40.
<ul><li>CHOLECALCIFEROL  (100 000 IU) is a safe, effective,   and simple way to increase calcidiol concentrations   </li><...
 
 
<ul><li>Oral / IM Ampoule </li></ul><ul><li>Containing   </li></ul><ul><li>5mg Cholecalciferol eq to 200,000 IU Cholecalci...
<ul><li>Dose </li></ul><ul><li>1 Ampoule  (200,000 IU)  every 6 months </li></ul><ul><li>Elderly </li></ul><ul><li>1/2  Am...
<ul><li>Thank You </li></ul>
Upcoming SlideShare
Loading in …5
×

Importance of vitamin d in orthopaedic patients

1,935 views

Published on

Importance of vitamin d in orthopaedic patients

Published in: Health & Medicine
0 Comments
4 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total views
1,935
On SlideShare
0
From Embeds
0
Number of Embeds
4
Actions
Shares
0
Downloads
75
Comments
0
Likes
4
Embeds 0
No embeds

No notes for slide
  • the results of a recent randomized, doubleblind, placebo-controlled trial ( n = 2686) demonstrated that
  • Importance of vitamin d in orthopaedic patients

    1. 1. Importance of Vitamin D In Orthopedic Patients
    2. 2. <ul><li>OSTEOPOROSIS </li></ul><ul><li>is highly prevalent, affecting approximately </li></ul><ul><li>one-third of women aged 60-70 years, and </li></ul><ul><li>two-thirds of those aged 80 years and older </li></ul><ul><li>200 MILLION WOMEN WORLDWIDE </li></ul>
    3. 3. <ul><li>OSTEOPOROSIS </li></ul><ul><li>is the major cause of FRACTURES </li></ul>1992;7:1005-10
    4. 4. <ul><li>40% OF WOMEN and 13% of men aged 50 years and older will sustain an </li></ul><ul><li>OSTEOPOROTIC FRACTURE in their remaining lifetime </li></ul>1992;7:1005-10
    5. 5. <ul><li>FRACTURES have a profound impact on QUALITY OF LIFE . </li></ul><ul><li>Approximately 20%-25% of women over age 50 years have had one or more </li></ul><ul><li>VERTEBRAL FRACTURE , the most common osteoporotic fracture </li></ul>
    6. 6. <ul><li>Both vertebral and hip fractures are associated with excess mortality. For instance, approximately 20% OF HIP FRACTURE PATIENTS aged 50 years and older </li></ul><ul><li>DIE WITHIN 1 YEAR </li></ul>2001;285:320-3
    7. 7. <ul><li>Patients being treated for OSTEOPOROSIS should be adequately supplemented with calcium and VITAMIN D to maximize the benefit of treatment </li></ul>2007;24(12):1017-29 Drugs & Aging
    8. 8. <ul><li>Studies have also demonstrated a correlation between </li></ul><ul><li>LOW SERUM VITAMIN D </li></ul><ul><li>& </li></ul><ul><li>INCREASED </li></ul><ul><li>RISK OF FALLS </li></ul>      2004;291:1999-2006
    9. 9. <ul><li>Studies have also demonstrated a correlation between </li></ul><ul><li>LOW SERUM VITAMIN D </li></ul><ul><li>& </li></ul><ul><li>FALLS-RELATED FRACTURES </li></ul>2003;18:343-51
    10. 10. <ul><li>Studies have also demonstrated a correlation between </li></ul><ul><li>LOW SERUM VITAMIN D </li></ul><ul><li>& </li></ul><ul><li>HIGHER RISK FOR HIP FRACTURE </li></ul>2008;149:242-250.
    11. 11. <ul><li>VITAMIN D RECEPTORS (VDRs) are known to be present in muscle tissue. </li></ul>2001 Jan;33(1):19-24. The Histochemical Journal
    12. 12. <ul><li>Studies have also demonstrated a correlation between </li></ul><ul><li>LOW SERUM VITAMIN D </li></ul><ul><li>& </li></ul><ul><li>AGE-RELATED MUSCLE WEAKNESS </li></ul>1986;7:434-8
    13. 13. <ul><li>Studies have also demonstrated a correlation between </li></ul><ul><li>LOW SERUM VITAMIN D </li></ul><ul><li>& </li></ul><ul><li>MUSCULOSKELETAL </li></ul><ul><li>PAIN </li></ul>2003;78:1463-70
    14. 14. <ul><li>Studies have also demonstrated a correlation between </li></ul><ul><li>LOW SERUM VITAMIN D </li></ul><ul><li>& </li></ul><ul><li>CHRONIC LOW BACK PAIN </li></ul>2003 Jan 15;28(2):177-9
    15. 15. <ul><li>Studies have also demonstrated a correlation between </li></ul><ul><li>LOW SERUM VITAMIN D </li></ul><ul><li>& </li></ul><ul><li>INCREASED </li></ul><ul><li>BODY SWAY </li></ul>2001;109:87-92
    16. 16. <ul><li>Lower concentrations of 25(OH)D are associated with significant BACK PAIN in older women </li></ul>2008 May;56(5):785-91.
    17. 17. <ul><li>Vitamin D deficiency is now recognized as a PANDEMIC </li></ul>2008 Apr;87(4):1080S-6S.
    18. 18. <ul><li>VITAMIN D Reduced the </li></ul><ul><li>RISK OF FALLS by More Than 20% Among Elderly Populations </li></ul>2004;291:1999-2006
    19. 19. <ul><li>100 000 IU VITAMIN D 3 every 4 months was safe and effective in decreasing the incidence of </li></ul><ul><li>OSTEOPOROTIC FRACTURES </li></ul><ul><li>by 33% compared with placebo </li></ul>2003 Mar 1;326(7387):469.
    20. 20. <ul><li>Repletion of VITAMIN D and at the Time of Fracture May Reduce Future Fracture Risk and FACILITATE </li></ul><ul><li>HIP FRACTURE REPAIR   </li></ul>1999;281:1505-1511.
    21. 21. <ul><li>A single high dose of VITAMIN D3 stimulated </li></ul><ul><li>FRACTURE HEALING </li></ul>1997;116(1-2):37-40.
    22. 22. <ul><li>CHOLECALCIFEROL (100 000 IU) is a safe, effective, and simple way to increase calcidiol concentrations </li></ul>Vol. 87, No. 3, 688-691, March 2008.
    23. 25. <ul><li>Oral / IM Ampoule </li></ul><ul><li>Containing </li></ul><ul><li>5mg Cholecalciferol eq to 200,000 IU Cholecalciferol </li></ul><ul><li>Light Resistant Ampoule Packaging </li></ul>
    24. 26. <ul><li>Dose </li></ul><ul><li>1 Ampoule (200,000 IU) every 6 months </li></ul><ul><li>Elderly </li></ul><ul><li>1/2 Ampoule (100,000 IU) every 3 months </li></ul>
    25. 27. <ul><li>Thank You </li></ul>

    ×