To assess if 2 successive US examinations could rule out the presence of clinically significant contralateral anomalies in neonates with MCDK
Followed 76 newborn infants with antenatally discovered MCDK
US within the first week and @ around 1 mo
VCUG and isotopic studies were performed in all infants
Ismaili K, Avni FE, Alexander M, Schulman C, Collier F, Hall M. Routine voiding cystourethrography is of no value in neonates with unilateral multicystic dysplastic kidney. J Pediatr. 2005 Jun;146(6):759-63.
VCUG: Ismaili et al 2005
61 (80% of total) had normal contralateral urinary tract on the 2 successive neonatal renal US scans
4 of 61 (7%) with low-grade VUR on VCUG resolved spontaneously before 2 years of age
Two successive normal neonatal renal ultrasound scans will rule out clinically significant contralateral anomalies
Routine VCUG is unnecessary
99m Tc-DTPA is purely glomerular agent GFR
99m Tc-MAG is partly secreted by renal tubules
99m Tc-DMSA for renal scaring
Dynamic study is used to detect any residual function.