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In addition to drug-drug interactions, "Food-drug interactions" can also cause adverse drug reactions or losses of efficacy and are thus important issues to consider in the evaluation of new drug candidates.
This is why drug agencies recommend conducting food-drug studies early in the development of new drugs. For example, the FDA advises the administration of a high-fat meal with new drugs to investigate potential food effect.
Aureus Sciences has developed a highly structured Knowledgebase, AurSCOPE ADME/DDI®, containing pharmacokinetics, metabolism and drug interactions data including reliable information about "Food-Drug interaction" studies extracted from journal articles and FDA reviews.
Knowledge from published data can help the pharmaceutical industry improve recommendations for regulatory agencies on how drugs should be taken when eating food, and to challenge prediction of food-drug interactions.
What you will learn
Similarities and differences of regulatory agencies recommendations on food-drug interaction
New insights about food-drug interactions including herbal, fruit, and dietary interactions based on clinical outcomes
Therapeutic classes, physico-chemical properties of drugs linked with high food-drug interactions