3rd Tinnitus Research Initiative Meeting                           24-26 June 2009, Stresa, Italy




       Tinnitusbook:...
Acufeni.net forum
www.acufeni.net
OUR PROJECT

     To create a new interdisciplinary online
      resource connecting researchers with
    researchers, to ...
3rd Tinnitus Research Initiative Meeting                           24-26 June 2009, Stresa, Italy




  Building Online Co...
Alzheimer Research Forum

• Created in 1996 www.alzforum.org
• 58,000 Alzheimer Disease (AD) Related
  Papers
• 1800 AD Re...
Alzheimer Research Forum
www.alzforum.org
58,000 AD Related Papers
6300 Scientists’ Comments
Over 80 Live Discussions
ARF - People

•   Executive Editor (June Kinoshita)
•   2 Managing Editors
•   3 Science Writers
•   3 Consultants (Elizab...
SWAN - Semantic Web
    Applications in Neuromedicine
• Define Hypotheses, Claims, Research
  Questions, Comments, Experim...
SWAN Model
http://hypothesis.alzforum.org
                                 SWAN Homepage
SWAN Hypotheses
SWAN Hypothesis
SWAN Claim


             Qualifiers

             Supportive
             Evidence

             Relationships
          ...
SWAN Graph [1]
SWAN Graph [2]
SWAN Graph [3]
Schizophrenia Research Forum
High Number of Resources
•   PubMed                •   Reagents
•   Mash Terminology      •   Experiments
•   Entrez Gene ...
Science Collaboration Framework

• Reusable software that can be used to
  develop web-based, collaborative, scientific
  ...
stembook.org
stembook.org

• It is an open access collection of invited,
  original, peer-reviewed chapters (46 a few
  days ago) cover...
Table of Contents
Example: Link to genes
Other Stem Book features

• eAlert
• Commenting and discussion forums
• Semiautomatic annotation of Genes in new
  article...
PDonline.org
What we can offer

• Experience in creating and maintain online
  communities
• Reusable software that can speed up the
  ...
Thank you
•   Tim Clark                  • Sudeshna Das
•   Gwen Wong                  • Benjamin Melançon
•   June Kinosh...
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Tinnitusbook

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A crucial new interdisciplinary resource for Tinnitus researchers

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Tinnitusbook

  1. 1. 3rd Tinnitus Research Initiative Meeting 24-26 June 2009, Stresa, Italy Tinnitusbook: a proposal for an advanced scientific web community for tinnitus research G. Attanasio (a,f), P. Ciccarese (b,c), E. Wu (e), T. Clark (b,c,d), E. Pecis (f), R. Filipo(a) a: Dept. Neurology and Otolaryngology, University La Sapienza, Rome, IT; b: Massachusetts Gen. Hosp., Boston, MA; c: Harvard Med. School, Boston, MA; d: Harvard Initiative in Innovative Computing, Cambridge, MA; e: Alzheimer Res. Forum Found., Boston, MA; f: Acufeni.net Association onlus
  2. 2. Acufeni.net forum www.acufeni.net
  3. 3. OUR PROJECT To create a new interdisciplinary online resource connecting researchers with researchers, to facilitate rapid progress in Tinnitus research COMMUNITY COMMUNITY OF PATIENTS OF SCIENTISTS
  4. 4. 3rd Tinnitus Research Initiative Meeting 24-26 June 2009, Stresa, Italy Building Online Communities for Scientists Tinnitusbook: a proposal for an advanced scientific web community for tinnitus research Paolo Ciccarese, PhD Mass General Hospital / Harvard Medical School In collaboration with paolo.ciccarese@gmail.com Alzheimer Research Forum
  5. 5. Alzheimer Research Forum • Created in 1996 www.alzforum.org • 58,000 Alzheimer Disease (AD) Related Papers • 1800 AD Related News Articles • Curated 14,700 Antibodies • 5000 Members (AD Scientists) • 6300 Scientists’ Comments • Over 80 live discussions > The CNN of Alzheimer
  6. 6. Alzheimer Research Forum www.alzforum.org
  7. 7. 58,000 AD Related Papers
  8. 8. 6300 Scientists’ Comments
  9. 9. Over 80 Live Discussions
  10. 10. ARF - People • Executive Editor (June Kinoshita) • 2 Managing Editors • 3 Science Writers • 3 Consultants (Elizabeth Wu for Knowledge Managment) • 1 Drug Database Curator (Gwen Wong, PhD) • 1 Event Coordinator • 1 Web Developer • 1 Production Assistant • 10 Advisory Board …and 5000 Scientists!!!
  11. 11. SWAN - Semantic Web Applications in Neuromedicine • Define Hypotheses, Claims, Research Questions, Comments, Experiments – To relate them in between each others – To relate them to Gene, Protein, Antibodies, Organisms • Annotate Publications (manual and semi- automatic) • Efficient browsing of the knowledge base • Knowledge sharing across communities
  12. 12. SWAN Model
  13. 13. http://hypothesis.alzforum.org SWAN Homepage
  14. 14. SWAN Hypotheses
  15. 15. SWAN Hypothesis
  16. 16. SWAN Claim Qualifiers Supportive Evidence Relationships with other statements in the KB Lses
  17. 17. SWAN Graph [1]
  18. 18. SWAN Graph [2]
  19. 19. SWAN Graph [3]
  20. 20. Schizophrenia Research Forum
  21. 21. High Number of Resources • PubMed • Reagents • Mash Terminology • Experiments • Entrez Gene • Neuro Imaging • UniProt • Models • Gene Ontology • Annotations • Alzforum Gene • Discussions • Alzforum Antibodies • Commentaries • Experimental Data • …
  22. 22. Science Collaboration Framework • Reusable software that can be used to develop web-based, collaborative, scientific communities • Support interdisciplinary scientists in publishing, annotating, sharing and discussing content such as articles, perspectives, interviews and news items, as well as assert personal biographies and research interests
  23. 23. stembook.org
  24. 24. stembook.org • It is an open access collection of invited, original, peer-reviewed chapters (46 a few days ago) covering a range of topics related to stem cell biology written by top researchers in the field at the Harvard Stem Cell Institute and worldwide. • ISSN 1940-3429
  25. 25. Table of Contents
  26. 26. Example: Link to genes
  27. 27. Other Stem Book features • eAlert • Commenting and discussion forums • Semiautomatic annotation of Genes in new articles • Access to the under-development clouds of resources for life science (genes, proteins, antibodies, organisms…)
  28. 28. PDonline.org
  29. 29. What we can offer • Experience in creating and maintain online communities • Reusable software that can speed up the process of creation of a new community • Access to biomedical knowledge bases • Access to new methods and technologies as result of our research • Be part of a community of communities
  30. 30. Thank you • Tim Clark • Sudeshna Das • Gwen Wong • Benjamin Melançon • June Kinoshita • Marco Ocana • Elizabeth Wu Paolo Ciccarese, PhD paolo.ciccarese@gmail.com
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