Tinnitusbook

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A crucial new interdisciplinary resource for Tinnitus researchers

A crucial new interdisciplinary resource for Tinnitus researchers

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  • 1. 3rd Tinnitus Research Initiative Meeting 24-26 June 2009, Stresa, Italy Tinnitusbook: a proposal for an advanced scientific web community for tinnitus research G. Attanasio (a,f), P. Ciccarese (b,c), E. Wu (e), T. Clark (b,c,d), E. Pecis (f), R. Filipo(a) a: Dept. Neurology and Otolaryngology, University La Sapienza, Rome, IT; b: Massachusetts Gen. Hosp., Boston, MA; c: Harvard Med. School, Boston, MA; d: Harvard Initiative in Innovative Computing, Cambridge, MA; e: Alzheimer Res. Forum Found., Boston, MA; f: Acufeni.net Association onlus
  • 2. Acufeni.net forum www.acufeni.net
  • 3. OUR PROJECT To create a new interdisciplinary online resource connecting researchers with researchers, to facilitate rapid progress in Tinnitus research COMMUNITY COMMUNITY OF PATIENTS OF SCIENTISTS
  • 4. 3rd Tinnitus Research Initiative Meeting 24-26 June 2009, Stresa, Italy Building Online Communities for Scientists Tinnitusbook: a proposal for an advanced scientific web community for tinnitus research Paolo Ciccarese, PhD Mass General Hospital / Harvard Medical School In collaboration with paolo.ciccarese@gmail.com Alzheimer Research Forum
  • 5. Alzheimer Research Forum • Created in 1996 www.alzforum.org • 58,000 Alzheimer Disease (AD) Related Papers • 1800 AD Related News Articles • Curated 14,700 Antibodies • 5000 Members (AD Scientists) • 6300 Scientists’ Comments • Over 80 live discussions > The CNN of Alzheimer
  • 6. Alzheimer Research Forum www.alzforum.org
  • 7. 58,000 AD Related Papers
  • 8. 6300 Scientists’ Comments
  • 9. Over 80 Live Discussions
  • 10. ARF - People • Executive Editor (June Kinoshita) • 2 Managing Editors • 3 Science Writers • 3 Consultants (Elizabeth Wu for Knowledge Managment) • 1 Drug Database Curator (Gwen Wong, PhD) • 1 Event Coordinator • 1 Web Developer • 1 Production Assistant • 10 Advisory Board …and 5000 Scientists!!!
  • 11. SWAN - Semantic Web Applications in Neuromedicine • Define Hypotheses, Claims, Research Questions, Comments, Experiments – To relate them in between each others – To relate them to Gene, Protein, Antibodies, Organisms • Annotate Publications (manual and semi- automatic) • Efficient browsing of the knowledge base • Knowledge sharing across communities
  • 12. SWAN Model
  • 13. http://hypothesis.alzforum.org SWAN Homepage
  • 14. SWAN Hypotheses
  • 15. SWAN Hypothesis
  • 16. SWAN Claim Qualifiers Supportive Evidence Relationships with other statements in the KB Lses
  • 17. SWAN Graph [1]
  • 18. SWAN Graph [2]
  • 19. SWAN Graph [3]
  • 20. Schizophrenia Research Forum
  • 21. High Number of Resources • PubMed • Reagents • Mash Terminology • Experiments • Entrez Gene • Neuro Imaging • UniProt • Models • Gene Ontology • Annotations • Alzforum Gene • Discussions • Alzforum Antibodies • Commentaries • Experimental Data • …
  • 22. Science Collaboration Framework • Reusable software that can be used to develop web-based, collaborative, scientific communities • Support interdisciplinary scientists in publishing, annotating, sharing and discussing content such as articles, perspectives, interviews and news items, as well as assert personal biographies and research interests
  • 23. stembook.org
  • 24. stembook.org • It is an open access collection of invited, original, peer-reviewed chapters (46 a few days ago) covering a range of topics related to stem cell biology written by top researchers in the field at the Harvard Stem Cell Institute and worldwide. • ISSN 1940-3429
  • 25. Table of Contents
  • 26. Example: Link to genes
  • 27. Other Stem Book features • eAlert • Commenting and discussion forums • Semiautomatic annotation of Genes in new articles • Access to the under-development clouds of resources for life science (genes, proteins, antibodies, organisms…)
  • 28. PDonline.org
  • 29. What we can offer • Experience in creating and maintain online communities • Reusable software that can speed up the process of creation of a new community • Access to biomedical knowledge bases • Access to new methods and technologies as result of our research • Be part of a community of communities
  • 30. Thank you • Tim Clark • Sudeshna Das • Gwen Wong • Benjamin Melançon • June Kinoshita • Marco Ocana • Elizabeth Wu Paolo Ciccarese, PhD paolo.ciccarese@gmail.com