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2/9/11 Ribosomes Presentation

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Transcript

  • 1. RIBOSOMES
    THE BEST ORGANELLE EVER
  • 2.
    • Protein Builders+ Synthesizers
    • 3. Read the RNA’s information and use it to create proteins (translation)
    WHAT DO THEY DO?
  • 4.
    • 5-10 nm larger in eukaryotic cells
    • 5. Made out of complexes of RNAs and proteins
    • 6. 2 subunits:
    • 7. smaller attaches to mRNA
    • 8. Larger binds to the tRNA and amino acids
    • 9. Then they split
    WHAT DO THEY LOOK LIKE?
  • 10.
    • Prokaryotes: free forms in cytoplasm and protoplasm
    • 11. Eukaryotes:
    • 12. free in cytoplasm for use inside cell
    • 13. attached to outer membrane of endoplasmic reticulum for use outside of cell
    WHERE DO THEY LIVE?
  • 14. PLANT AND ANIMAL CELLS
    PLANT
    ANIMAL
  • 15. WHAT HAPPENS WHEN THEY DON’t work right?
    • Diamond-BlackfanAnemia
    • 16. 5 infants/million
    • 17. Heart and skeletal abnormalities, not enough red blood cells
    • 18. The 7 mutated genes give faulty instructions on how to make ribosomal proteins
    • 19. Cartilage Hair Hypoplasia
    • 20. Relatively rare, but 1/19 of the Amish population are carriers
    • 21. Anemic, short limbs, leukopenia (low white blood cell count) and thrombocytopenia (low platelet count)
    • 22. The gene mutation causes a buildup of one enzyme which builds ribosomal RNA
    • 23. Shwachman-Diamond Syndrome
    • 24. 1/100,000 children
    • 25. Neutropenia (low white blood cell count) and Pancreatic problems that lead to steatorrhea (fatty bowel movement) because there aren’t enough enzymes to digest fats, anemia
    • 26. The gene mutation is causing a low amount of enzymes made out of proteins
    • 27. Dyskeratosis Congenita
    • 28. 1/million children
    • 29. Hair, nail, skin, lungs, blood, digestive and immune system abnormalities, aplastic anemia (bone marrow doesn’t make enough platelets, red or white blood cells),
    • 30. Caused by gene mutation that causes ribosome deficiency
  • PHOTO CREDITS
    Slide 2: http://biology.about.com/b/2008/11/29/what-are-ribosomes.htm
    Slide 3: http://barrett-group.mcgill.ca/teaching/nanotechnology/ribosome.jpg
    Slide 4:http://web.jjay.cuny.edu/~acarpi/NSC/images/cell.gif
    Slide 6:http://illnessesanimalsplants.wikispaces.com/file/view/plantcell.jpg/31816717/plantcell.jpg
    http://images.protopage.com/view/721661/caa3z4ysta5s87lr2asekq5ng.jpg
  • 31. Bibliography
    • http://en.wikipedia.org/wiki/Ribosome (February 2011)
    • 32. http://www.biology4kids.com/files/cell_ribos.html (February 2011)
    • 33. http://www.cs.stedwards.edu/chem/Chemistry/CHEM43/CHEM43/Ribosomes/Ribosome.HTML (February 2011)
    • 34. http://www.livestrong.com/article/208980-what-is-a-list-of-ribosomes-diseases/ (February 2011)