A simple eye exam is usually enough to detect retinoblastoma, although a more thorough examination is usually necessary to confirm its presence.
An ophthalmoscope, commonly used during eye exams to, among other things, check for eye cancers such as retinoblastoma. More complex methods, such as retinal scans (result shown here), are often necessary to confirm the existence of retinoblastoma .
The gene is known as RB1, which stands for retinoblastoma 1.
It codes for the production of the pRB protein, which is a tumor suppressor. Its purpose is to control the replication of cells, and keep them from replicating too quickly, which is what cancer essentially is.
The National Cancer Institute’s site about retinoblastoma. Gives info about the disease, as well as treatment options. There is plenty of info about retinoblastoma research, links to studies, and the like.
"Retinoblastoma." Lisa Andres, M.S., C.G.C. and Rebecca J. Frey, PhD The Gale Encyclopedia of Cancer: A Guide to Cancer and Its Treatments. Ed. Jacqueline L. Longe. 3rd ed. Detroit: Gale, 2010. 2 vols.
"Retinoblastoma." Edward R. Rosick, DO, MPH, MS. The Gale Encyclopedia of Genetic Disorders. Ed. Laurie Fundukian. 3rd ed. Detroit: Gale, 2010. 2 vols.