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REGIONAL ENTERITIS  (CROHN’S DISEASE)
CRONH’S DISEASE <ul><li>is a lifelong inflammatory bowel disease (IBD).   </li></ul><ul><li>is a chronic, recurrent inflam...
ANATOMY
CAUSES <ul><li>The exact cause of Crohn disease remains unknown.  </li></ul><ul><li>Current theories suggest that genetics...
<ul><li>Crohn disease apparently is not caused by emotional distress.  </li></ul><ul><li>Crohn disease definitely runs in ...
 
CLINICAL MANIFESTATION <ul><li>Prominent abdominal pain & diarrhea. </li></ul><ul><li>Crampy pains occur after meal. </li>...
DIAGNOSTIC PROCEDURE <ul><li>Barium X-rays studies. </li></ul><ul><li>Colonoscopy or flexible sigmoidoscopy . </li></ul><u...
MEDICAL MANAGEMENT <ul><li>TREATMENT: </li></ul><ul><li>Anti-inflammatory drugs </li></ul><ul><li>Sulfasalazine </li></ul>...
<ul><li>b.  Methotrexate.  </li></ul><ul><li>c.  Infliximab.  </li></ul><ul><li>d.  Azathioprine. </li></ul><ul><li>3.  An...
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Cronhs Disease

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  • The pictures really added to the great content.

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  • Wonderful presentation. The pictures and images added a lot to the well presented information about Crohn's Disease.
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Transcript of "Cronhs Disease"

  1. 1. REGIONAL ENTERITIS (CROHN’S DISEASE)
  2. 2. CRONH’S DISEASE <ul><li>is a lifelong inflammatory bowel disease (IBD). </li></ul><ul><li>is a chronic, recurrent inflammatory disease of the intestinal tract. </li></ul>
  3. 3. ANATOMY
  4. 4. CAUSES <ul><li>The exact cause of Crohn disease remains unknown. </li></ul><ul><li>Current theories suggest that genetics, environment, diet, blood vessel abnormalities, and/or even psychosocial factors cause Crohn disease. </li></ul><ul><li>Probably the most popular theory is that Crohn disease is caused by the immune system overreacting to infection by a virus or bacterium. </li></ul>
  5. 5. <ul><li>Crohn disease apparently is not caused by emotional distress. </li></ul><ul><li>Crohn disease definitely runs in families. People who have Crohn disease may have an inherited predisposition to abnormal immunologic response to one or more provoking factors. </li></ul>
  6. 7. CLINICAL MANIFESTATION <ul><li>Prominent abdominal pain & diarrhea. </li></ul><ul><li>Crampy pains occur after meal. </li></ul><ul><li>Blood in your stool. </li></ul><ul><li>Fever and Leukocytosis occur. </li></ul><ul><li>Symptoms extend beyond the GI tract to include joint problems, skin lesions, ocular disorders and oral ulcers. </li></ul><ul><li>Reduced appetite and weight loss. </li></ul>
  7. 8. DIAGNOSTIC PROCEDURE <ul><li>Barium X-rays studies. </li></ul><ul><li>Colonoscopy or flexible sigmoidoscopy . </li></ul><ul><li>Biopsy . </li></ul><ul><li>Stool analysis. </li></ul><ul><li>Complete blood count (CBC). </li></ul><ul><li>Computerized tomography (CT). </li></ul>
  8. 9. MEDICAL MANAGEMENT <ul><li>TREATMENT: </li></ul><ul><li>Anti-inflammatory drugs </li></ul><ul><li>Sulfasalazine </li></ul><ul><li>Mesalamine </li></ul><ul><li>Corticosteroids. </li></ul><ul><li>2. Immune system suppressors </li></ul><ul><li>a. Cyclosporine </li></ul>
  9. 10. <ul><li>b. Methotrexate. </li></ul><ul><li>c. Infliximab. </li></ul><ul><li>d. Azathioprine. </li></ul><ul><li>3. Antibiotics </li></ul><ul><li>Metronidazole (Flagyl). </li></ul><ul><li>Ciprofloxacin (Cipro). </li></ul>
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