Cronhs Disease

REGIONAL ENTERITIS (CROHN’S DISEASE)

CRONH’S DISEASE
is a lifelong inflammatory bowel disease (IBD).
is a chronic, recurrent inflammatory disease of the intestinal tract.

ANATOMY

CAUSES
The exact cause of Crohn disease remains unknown.
Current theories suggest that genetics, environment, diet, blood vessel abnormalities, and/or even psychosocial factors cause Crohn disease.
Probably the most popular theory is that Crohn disease is caused by the immune system overreacting to infection by a virus or bacterium.

Crohn disease apparently is not caused by emotional distress.
Crohn disease definitely runs in families. People who have Crohn disease may have an inherited predisposition to abnormal immunologic response to one or more provoking factors.

CLINICAL MANIFESTATION
Prominent abdominal pain & diarrhea.
Crampy pains occur after meal.
Blood in your stool.
Fever and Leukocytosis occur.
Symptoms extend beyond the GI tract to include joint problems, skin lesions, ocular disorders and oral ulcers.
Reduced appetite and weight loss.

DIAGNOSTIC PROCEDURE
Barium X-rays studies.
Colonoscopy or flexible sigmoidoscopy .
Biopsy .
Stool analysis.
Complete blood count (CBC).
Computerized tomography (CT).

MEDICAL MANAGEMENT
TREATMENT:
Anti-inflammatory drugs
Sulfasalazine
Mesalamine
Corticosteroids.
2. Immune system suppressors
a. Cyclosporine

b. Methotrexate.
c. Infliximab.
d. Azathioprine.
3. Antibiotics
Metronidazole (Flagyl).
Ciprofloxacin (Cipro).

Cronhs Disease

by arviegrace aban on Sep 29, 2008

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