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Making Cinnamon inFUSED Wear
         part 1 - History & Uses

       part 2 - Scientific Research




     www.aromanticwear.com
This presentation is for
information purposes only
      and should not be
   interpreted as specific
      medical advice.
Centuries of Cinnamon




      Illustration of Powdered Saigon Cinnamon
   Sayre: A Manual of organic materia medica and pharmacognosy
                       Courtesy of http://www.archive.org/
Why Cinnamon

aromatic
                                   antibacterial

           anti-inflammatory properties

stimulates blood circulation

                                          natural
In the Quảng Nam Province
of Vietnam live some of the
  most vibrant cinnamon
 trees in the world, a land
    with a centruies old
  tradition of growing &
  harvesting the regions
     prized cinnamon




   Cinnamomum loureirii has thrived in the central
highlands of Vietnam for centuries. Its cinnamon trees
are said to contain the highest percent of the medicinal
       component of cinnamon found in its oil -
Baby Cinnamon Trees - Bloom
Farmers tend the entire life cycle until final harvest and
                      grading
The medicinal componet
 of Cinnamon is derived
       from its Oil




        Which is derived from
        the leaves, bark and
          sometimes roots
After sunlight curing, cinnamon tree
parts are left intact or combined with
        other raw materials

         drying cinnamon bark
Traditional & Modern Fabrication
PERSONAL WEAR
PERSONAL CARE
ALL PARTS OF THE CINNAMON parts ARE USED
 products are made from all TREE of the tree
End of Part 1 - Thank You !




 ~ Part 2 next . . .
PART 2

Scientific Research
For complete references of the Monograph
of Cinnamon (Cinnamomum spp.) and research,
    please reference The Natural Standard
            www.naturalstandard.com
                       or
   the for the brief version www.aromanticwear.com
The Research in this document is derived from
                   The Natural Standard
                      www.naturalstandard.com




                      Natural Standard Monograph
                   Cinnamon (Cinnamomum spp.)
                             Copyright © 2011
                  Commercial Distribution Prohibited
                                    ~
  This monograph is intended informational purposes only,

  and should not be interpreted as specific medical advice.

You should consult with a qualified healthcare provider before

 making decisions about therapies and/or health conditions.
Cinnamon (Cinnamomum spp.)
  1-methoxy-4-(1-propenyl) benzene (transanethole), 2-substituted 4-(3H)-


           r e l a t e d
 quinazolinones,3-phenyl-2-propen-l-ol (cinnamyl alcohol), 5,7,3',4'-tetrahydroxyflavan-3,4-diol,
aitokaneli (Finnish), äkta kanel (Swedish), akupatri (Telugu), albero della cannella (Italian),

  alpha-amyl cinnamaldehyde, American cinnamon, Batavia cassia, Batavia cinnamon,
   breyne, canela               (Portuguese, Spanish), canela de la China (Portuguese,
     Spanish), caneleiro (Portuguese), canelero chino (Spanish), canelero                de
   Ceilán (Spanish), canelheira da India (Portuguese-Brazil), cannelier                  de
 Chine (French), cannella (Italian), cannella del Ceylan (Italian), cannella della Cina
 (Italian), cannelle (French), cannelle de Ceylan (French), cannelle de Chine (French),
   cannelle de Cochinchine (French), cannellier casse (French), cannellier de Ceylan
  (French), cannellier de Chine (French), cassia(English, Italian), cássia (Portuguese),


                t e r m s
cássia-aromática (Portuguese), cassia bark,cassia-bark tree, cassia cinnamon, cassia
  lignea, cassia rou gui, catechins,       cây que(Vietnamese),                Ceylon
  cinnamon, ceyloni fahéj (Hungarian), ceyloninkaneli (Finnish),ceylonkanel (Swedish),
                    ceylonski cimet (Croatian), Ceylonzimt (German),
Cinnamon (Cinnamomum spp.)




        r e l a t e d
Ceylonzimtbaum (German), chadana (Sanskrit), chek tum phka loeng (Khmer),
 Chinazimt (German), Chinese-cassia, Chinese cinnamon, Chinesischer Zimt (German),
Chinesischer Zimtbaum (German), cin tarçını (Turkish), cinnamal, cinnamaldehyde,
cinnamate, cinnamic acid, cinnamic aldehyde, cinnamom-dhal chini Cinnamomi cassiae,
  Cinnamomi cassiae cortex, Cinnamomi ceylanici cortex, Cinnamomi cortex,
Cinnamomi flos, Cinnamomi osmophloeum, Cinnamomi ramulus,
 Cinnamomom, Cinnamomum aromaticum, Cinnamomum aromaticum Nees,
  Cinnamomum burmannii, Cinnamomum cassia, Cinnamomum cassia Blume,
          Cinnamomum cassia J. Presl, Cinnamomum cinnamon,
 Cinnamomum loureiroi, Cinnamomum mairei Levl., Cinnamomum migao,
Cinnamomum obtusifolium, Cinnamomum osmophloeum clones (A and B), Cinnamomum



           t e r m s
    osmophloeum Kaneh., Cinnamomum sieboldii, Cinnamomum Cinnamomum
  osmophloeum Kaneh., Cinnamomum sieboldii, Cinnamomum sieboldii
                            Meissn.,
                     Cinnamomum tamala,
Background
        Cinnamon has been used as a spice in several cultures for centuries.
  It was traditionally used to relieve stomach pain and gas; it is still used for these
conditions today. The bark of two cinnamon species (Cinnamomum zeylanicum and
              Cinnamomum cassia) is used as a spice (cinnamon bark)

  There is a lack of scientific information to support the use of cinnamon for any
condition. However, laboratory studies suggest that cinnamon may be useful in the
       treatment of diabetes (type 2) due to its blood sugar-lowering effects.

         Furthermore, cinnamon and its constituents may
 have anti-inflammatory, antibacterial, antifungal,
and antioxidant properties, and it may prove effective in
the supportivetreatment of conditions such as cancer or
                severe virus infections.
Uses Based scientific on evidence


  These uses have been tested in humans or animals.

    Safety and effectiveness have not always been

   proven. Some of these conditions are potentially

    serious, and should be evaluated by a qualified

                 healthcare provider.
Uses Based scientific on evidence



                        Angina (chest pain)
The use of cinnamon for bacterial angina has been reviewed. However,
well- designed trials are needed before a firm conclusion can be made.



                              Antioxidant
Based human study, a dried aqueous extract of cinnamon (Cinnulin PF®) may improve
the antioxidant status of overweight or obese individuals with impaired fasting glucose.
     More well-designed trials are needed before a firm conclusion can be made.
Uses Based scientific on evidence



  Cinnamon has been granted GRAS (Generally
Recognized as Safe) status as a food additive by the U.S.
        Food and Drug Administration (FDA).

GRAS substances are considered safe by the experts and not
   restricted, as is the case with other food additives.
Uses Based scientific on evidence



                      Allergic rhinitis
 Preliminary evidence suggests that cinnamon may have antiallergic
 properties. Based on human study, a combination product including
 Cinnamomum zeylanicum, Malpighia glabra, and Bidens pilosa has
demonstrated reduced allergic nasal symptoms in patients with allergic
rhinitis. More well-designed trials are needed before a firm conclusion
                             can be made.
Uses Based scientific on evidence



                  Bacterial Infection
Preliminary study suggests that cinnamon may treat bacterial infections
  including chronic salmonellosis. However, well-designed trials are
            needed before a firm conclusion can be made.


                        Candidiasis
Preliminary evidence suggests that cinnamon may have activity agains
   Candida. However, well-designed trials are needed before a firm
                      conclusion can be made.
Uses Based scientific on evidence


                             Diabetes
Based on human study, cinnamon has been used to control blood sugar;
  however, results have been mixed in other studies. Further study is
           needed before a firm conclusion may be made.

                        Eye disorders
 Preliminary data suggests that a combination herbal eye drop preparation
     (OphthaCare) may be useful in the treatment of various ophthalmic
   disorders including: conjunctivitis, conjunctival xerosis (dry eye), acute
   dacryocystitis, degenerative conditions (pterygium or pinguecula), and
 disorders in postoperative cataract patients. However, well-designed trials
             are needed before a firm conclusion can be made.
Uses Based scientific on evidence



        Helicobacter pylori infection
 Preliminary evidence suggests that cinnamon extracts may be effective
  against Helicobacter pylori. Based on human study, cinnamon extract
    was ineffective in ridding of H. pylori. However, the combination of
   cinnamon with other antimicrobials, or cinnamon extract at a higher
concentration, may prove useful. Further well-designed trials are needed
                  before a firm conclusion can be made.
Uses Based scientific on evidence



                     Insect repellant
Preliminary evidence suggests that cassia oil (Cinnamomum cassia) may
reduce dust mites. Based on human study, cinnamon may be useful as a
mosquito repellant. However, well-designed trials are needed before a firm
                        conclusion can be made

                        Lung cancer
Preliminary study suggests that cinnamon may be useful in the treatment of
    lung cancer. However, well-designed trials are needed before a firm
                        conclusion can be made.
Uses Based scientific on evidence



            Metabolic syndrome
          (coronary heart disease)
  Preliminary study suggests that cinnamon may be useful in
the treatment of features of metabolic syndrome in prediabetic
 subjects. However, well-designed trials are needed before a
                 firm conclusion can be made.
Uses based on tradition or theory




The below uses are based on tradition or scientific theories. They
often have not been thoroughly tested in humans, and safety and
   effectiveness have not always been proven. Some of these
 conditions are potentially serious, and should be evaluated by a
                  qualified healthcare provider.
Uses based on tradition or
             theory

 Abdominal pain, abortifacient (induces abortion), abscess, acaricidal
   (kills mites), acne, Alzheimer’s disease, analgesic (pain reliever),
anesthetic, anthelmintic (expels parasitic worms), anticoagulant (stops
blood from clotting), antidepressant, anti-inflammatory, antimutagenic,
   antiparasitic, antiplatelet (interferes with the blood ability to clot),
  antipyretic (reduces fever), antiseptic, antispasmodic (suppresses
   spasms), antiviral, arrhythmia, arthritis, asthma, benign prostatic
hyperplasia, bloating, blood purification, bronchitis, chronic bronchitis,
        chronic diarrhea, cognitive function, colds/flu, colic, cough,
Uses based on tradition or
            theory

     Cystitis (inflammation of urinary bladder), dental caries
  (cavities), deodorant, dermatitis (inflammation of the skin),
diarrhea, digestive aid, digestive disorders, diuretic (increases
 urination), dyspepsia (indigestion), eczema, emmenagogue
   (stimulates menstruation), flavoring, food poisoning, food
preservation, food uses, gastric ulcer, gastritis (stomach lining
   inflammation), gout, gum disease, gynecologic disorders,
       HIV/AIDS, hypercholesterolemia (high cholesterol),
 hypertension (high blood pressure), hyperthyroid (overactive
  thyroid gland), immunostimulation (stimulates the immune
                            system),
Uses based on tradition or
             theory

Inflammatory conditions, kidney disorders, lice, liver disease, long-
  term debility, loss of appetite, memory loss, movement disorders,
   muscle aches, nausea, neuralgia (nerve pain), neuroprotective,
     premature ejaculation, respiratory tract infection, rheumatoid
   arthritis, sciatica, sinusitis, skin conditions, snake repellent, sore
throat, spermicide, toothache, tumors, urethritis (inflammation of the
    urethra), urinary disorders, viral infections, weight gain, wound
                                    healing.
DOSING


     The below doses are based on scientific research,
 publications, traditional use, or expert opinion. Many herbs
  and supplements have not been thoroughly tested, and
safety and effectiveness may not be proven. Brands may be
 made differently, with variable ingredients, even within the
same brand. The below doses may not apply to all products.
 You should read product labels, and discuss doses with a
    qualified healthcare provider before starting therapy.
DOSING


                         Adults (over 18 years old)
 There are no proven effective medicinal doses for cinnamon. Cinnamon is
likely safe when taken by mouth short-term (up to six weeks) in dosages up
         to 6 grams daily and in amounts commonly found in foods.
                                     ~
 As an antioxidant, capsules containing 250 milligrams of cinnamon extract
(Cinnulin PF®) twice daily for 12 weeks. For candidiasis, eight lozenges of a
 commercially available cinnamon candy were taken daily for one week; for
oral candidiasis, a solution, made by cooking 250 grams of cinnamon in 2000
                  milliliters of water on medium heat until there
  was 500 milliliters of solution (solution defined as 50% cinnamon solution)
  has been used. This solution has been gargled 4-6 times a day and each
                    time with 20-30 milliliters of the solution.
DOSING


 For diabetes, various doses of cinnamon (capsules, powder, extract)
have been studied. 1-6 grams of cinnamon daily has been used for up
    to 90 days. For Helicobacter pylori infection, 80 milligrams of
    cinnamon extract daily was used for four weeks. For metabolic
    syndrome, 500 milligrams of a water-soluble cinnamon extract,
         Cinnulin PF®, is recommended by the manufacturer.
  As an insect repellant, variousdoses have been studied including a
single application of cream containing 5% (w/w) cassia oil (containing 5
               grams of cassia oil) for up to 120 minutes.
SAFETY
                Children (under 18 years old)
There is no proven safe or effective medicinal dose of cinnamon in children.
                                --------
    The U.S. Food and Drug Administration does not strictly regulate
    herbs and supplements. There is no guarantee of strength, purity or
safety of products, and effects may vary. You should always read product
 labels. If you have a medical condition, or are taking other drugs, herbs,
  or supplements, you should speak with a qualified healthcare provider
                           before starting a new
   therapy. Consult a healthcare provider immediately if you experience
                                side effects.
Allergies

   Avoid in individuals with a

        known allergy or

  hypersensitivity to cinnamon,
        its constituents,

members of the Lauraceae family,
      or Balsam of Peru.
Side Effects and Warnings

     Cinnamon is likely safe when taken by mouth short-term.
   As with any spice or drug, cinnamon can be contaminated by
 microorganisms during storage. Caution is advised when choosing
                        cinnamon products.

Some people may be allergic or sensitive to cinnamon, but this is rare.
 Skin rash and inflammation, mouth sores, tongue inflammation, gum
                   disease, acne, mouth lesions, and
inflammation of the lips have been noted after applying cinnamon (e.g.
 cinnamon oils, flavored chewing-gums, mints, or toothpastes) on the
                             mouth or face.
Side Effects and Warnings

Cinnamaldehyde (the chemical compound that gives cinnamon
its spice) may cause swelling of the lips,mouth tissue, and the
            face, hives, skin rash, and mouth sores.

  Prolonged exposure tocinnamon-flavored gum may cause
 cancer. Asthma and other breathing difficulties were seen in
  spice-factory workers. Large amounts of cinnamon may be
      toxic to the liver due to possible coumarin content.

Caution is advised when using other medications that may be
                hepatotoxic (toxic to the liver).
Side Effects and Warnings

 Although not well studied in humans, large amounts of cinnamon
 (more than those found in foods) should be avoided in pregnant
women due to possible abortion inducing effects. Use cautiously in
    patients taking drugs that affect the function of the immune
     system. Use cautiously in patients taking drugs that lower
                            cholesterol.
 Although not well studied in humans, cinnamon bark may cause
 decrease in platelet counts in the blood after long-term use. Use
cautiously in patients taking drugs, herbs, or supplements broken
  down by the liver. Use cautiously in patients with liver damage.
Side Effects and Warnings

    Cinnamon may lower blood sugar levels.
 Use cautiously in patients with diabetes or low
           blood sugar (hypoglycemia).
      Cinnamon may enhance the effect of
     antibiotics.Cinnamon may interact with
cardiovascular (heart) agents, due to its several
effects on blood and the cardiovascular system
         (e.g. antiarrhythmic properties).
 Use cautiously in people with heart conditions
Side Effects and Warnings

        Pregnancy & Breastfeeding
Cinnamon is not recommended in medicinal amounts in pregnant or
 breastfeeding women due to a lack of available scientific evidence
  Although not well studied in humans, large amounts of cinnamon
  (more than those found in foods) should be avoided in pregnant
         women due to possible abortion inducing effects.
Cinnamon may act as a spermicide, thereby preventing pregnancy
                            by killing sperm;
      however, it is not recommended as a form of birth control.
INTERACTIONS

Most herbs and supplements have not been thoroughly tested
   for interactions with other herbs, supplements, drugs, or
 foods. The interactions listed below are based on reports in
 scientific publications, laboratory experiments, or traditional
  use. You should always read product labels. If you have a
    medical condition, or are taking other drugs, herbs, or
  supplements, you should speak with a qualified healthcare
             provider before starting a new therapy.
INTERACTIONS with Drugs


  Cinnamon may have antibacterial activity. Use cautiously with antibiotic medications,
  due to possible additive effects. Cinnamon may lower blood sugar levels. Caution is
advised when using medications that may also lower blood sugar. Patients taking drugs
 for diabetes by mouth or insulin should be monitored closely by a qualified healthcare
          professional, including a pharmacist. Medication adjustments may be
   necessary.Cinnamon may increase the risk of bleeding when taken with drugs that
  increase the riskof bleeding. Some examples include aspirin, anticoagulants (“blood
     thinners”) such aswarfarin (Coumadin®) or heparin, anti-platelet drugs such as
   clopidogrel (Plavix®), and non-steroidal anti-inflammatory drugs (NSAIDS) such as
      ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®). The antifungal
     properties of cinnamon may enhance the effect of commonly used antifungals.
        Cinnamon may have antispasmodic effects. Use cautiously if taking other
  antispasmodics. Cinnamon bark extract may have antiviral effects. Use cautiously if
   taking antiviral medications, due to possible additive effects. Cinnamon may affect
heart rate and thus may interact with heart rate regulating agents.Caution is advised in
                         people taking agents for heart conditions.
INTERACTIONS with Drugs

  Cinnamon may interfere with the way the body processes certain drugs using the
   liver’s “cytochrome P450” enzyme system. As a result, the levels of drugs in the
    blood may be altered.Cinnamon may have effects on the immune system. Use
 cautiously with other agents that alter the immune system. Consult with a qualified
healthcare professional, including a pharmacist, to check for interactions.Cinnamon
  may lower cholesterol. Caution is advised when using medications that may also
  lower cholesterol.Cinnamon may lower blood pressure. Caution is advised when
 using medications that may also lower blood pressure. Cinnamon may be toxic to
    the liver in large amounts due to possible coumarin content. Caution is advised
when using other medications that may be hepatotoxic (toxic to the liver). Cinnamon
      may interact with alcohol, drugs that are used to treat Alzheimer’s disease,
  analgesics (pain relievers), drugs that decrease inflammation, anti-cancer drugs,
    anti-obesity drugs, aspirin, dexamethasone, drugs that affect GABA, estrogen,
              indomethacin, sympathomimetics, terfenadine, or tetracycline.
Interactions with Herbs & Dietary
            Supplements
       Cinnamon may have antibacterial activity.Use cautiously with
   antibacterial herbs and supplements, due tpossible additive effects
 Cinnamon may lower blood sugar levels. Caution is advised in patients
with diabetes or hypoglycemia, and in those taking herbs or supplements
that affect blood sugar. Serum glucose levels may need to be monitored
by a qualified healthcare professional, including a pharmacist, and doses
 may need adjustment.Cinnamon may increase the risk of bleeding when
 taken with herbs and supplements that are believed to increase the risk of
   bleeding. Multiple cases of bleeding have been reported with the use of
Ginkgo biloba, and fewer cases with garlic and saw palmetto.The antifungal
   properties of cinnamon may enhance the effects of commonly used
      antifungals. Cinnamon bark has been shown to contain very high
                        concentrations of antioxidants.
Interactions with Herbs & Dietary
             Supplements
    Use cautiously with herbs and supplements that are taken for their antioxidant
 effects, due to possible additive effects.Cinnamon may have antispasmodic effects.
  Use cautiously with other antispasmodics.Cinnamomum cassia bark extract may
   have antiviral effects. Use cautiously with antiviral herbs or supplements, due to
possible additive effects. Cinnamon may affect heart rate and thus may interact with
heart rate regulating agents.People taking herbs or supplements that alter heart rate
  should use cinnamon with caution.Cinnamon may interfere with the way the body
processes certain herbs or supplements using the liver’s “cytochrome P450” enzyme
   system. As a result, the levels of other herbsor supplements in the body may be
   altered.Cinnamon may have effects on the immune system; use cautiously with
                        herbs and supplements with similar effects.
  Cinnamon may lower cholesterol; use cautiously with herbs and supplements with
 similar effectsCinnamon may lower blood pressure. Caution is advised when using
 other herbs or supplements that may also lower blood pressure.Cinnamon may be
          toxic to the liver in large amounts due to possible coumarin content.
Interactions with Herbs & Dietary
            Supplements


 Caution is advised when using other herbs or supplements that
               may be hepatotoxic (toxic to the liver).
Cinnamon may interact with herbs or supplements that are used
     to treat Alzheimer’sdisease, analgesics (pain relievers),
        herbs or supplements that decrease inflammation,
     anti-cancer herbs or supplements, anti-obesity herbs or
      supplements, herbs or supplements that affect GABA
, herbs or supplements with hormonal effects, clove, ephedra, or
                            artemisia.
References


   This information is based on a systematic review of scientific
literature, and was peer- reviewed and edited by contributors to
          the Natural Standard Research Collaboration

                  www.naturalstandard.com


           Please see monograph for full references*

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Cinnamon inFUSED Products

  • 1. Making Cinnamon inFUSED Wear part 1 - History & Uses part 2 - Scientific Research www.aromanticwear.com
  • 2. This presentation is for information purposes only and should not be interpreted as specific medical advice.
  • 3. Centuries of Cinnamon Illustration of Powdered Saigon Cinnamon Sayre: A Manual of organic materia medica and pharmacognosy Courtesy of http://www.archive.org/
  • 4. Why Cinnamon aromatic antibacterial anti-inflammatory properties stimulates blood circulation natural
  • 5. In the Quảng Nam Province of Vietnam live some of the most vibrant cinnamon trees in the world, a land with a centruies old tradition of growing & harvesting the regions prized cinnamon Cinnamomum loureirii has thrived in the central highlands of Vietnam for centuries. Its cinnamon trees are said to contain the highest percent of the medicinal component of cinnamon found in its oil -
  • 7.
  • 8.
  • 9.
  • 10. Farmers tend the entire life cycle until final harvest and grading
  • 11. The medicinal componet of Cinnamon is derived from its Oil Which is derived from the leaves, bark and sometimes roots
  • 12. After sunlight curing, cinnamon tree parts are left intact or combined with other raw materials drying cinnamon bark
  • 13. Traditional & Modern Fabrication
  • 16. ALL PARTS OF THE CINNAMON parts ARE USED products are made from all TREE of the tree
  • 17. End of Part 1 - Thank You ! ~ Part 2 next . . .
  • 19. For complete references of the Monograph of Cinnamon (Cinnamomum spp.) and research, please reference The Natural Standard www.naturalstandard.com or the for the brief version www.aromanticwear.com
  • 20. The Research in this document is derived from The Natural Standard www.naturalstandard.com Natural Standard Monograph Cinnamon (Cinnamomum spp.) Copyright © 2011 Commercial Distribution Prohibited ~ This monograph is intended informational purposes only, and should not be interpreted as specific medical advice. You should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.
  • 21. Cinnamon (Cinnamomum spp.) 1-methoxy-4-(1-propenyl) benzene (transanethole), 2-substituted 4-(3H)- r e l a t e d quinazolinones,3-phenyl-2-propen-l-ol (cinnamyl alcohol), 5,7,3',4'-tetrahydroxyflavan-3,4-diol, aitokaneli (Finnish), äkta kanel (Swedish), akupatri (Telugu), albero della cannella (Italian), alpha-amyl cinnamaldehyde, American cinnamon, Batavia cassia, Batavia cinnamon, breyne, canela (Portuguese, Spanish), canela de la China (Portuguese, Spanish), caneleiro (Portuguese), canelero chino (Spanish), canelero de Ceilán (Spanish), canelheira da India (Portuguese-Brazil), cannelier de Chine (French), cannella (Italian), cannella del Ceylan (Italian), cannella della Cina (Italian), cannelle (French), cannelle de Ceylan (French), cannelle de Chine (French), cannelle de Cochinchine (French), cannellier casse (French), cannellier de Ceylan (French), cannellier de Chine (French), cassia(English, Italian), cássia (Portuguese), t e r m s cássia-aromática (Portuguese), cassia bark,cassia-bark tree, cassia cinnamon, cassia lignea, cassia rou gui, catechins, cây que(Vietnamese), Ceylon cinnamon, ceyloni fahéj (Hungarian), ceyloninkaneli (Finnish),ceylonkanel (Swedish), ceylonski cimet (Croatian), Ceylonzimt (German),
  • 22. Cinnamon (Cinnamomum spp.) r e l a t e d Ceylonzimtbaum (German), chadana (Sanskrit), chek tum phka loeng (Khmer), Chinazimt (German), Chinese-cassia, Chinese cinnamon, Chinesischer Zimt (German), Chinesischer Zimtbaum (German), cin tarçını (Turkish), cinnamal, cinnamaldehyde, cinnamate, cinnamic acid, cinnamic aldehyde, cinnamom-dhal chini Cinnamomi cassiae, Cinnamomi cassiae cortex, Cinnamomi ceylanici cortex, Cinnamomi cortex, Cinnamomi flos, Cinnamomi osmophloeum, Cinnamomi ramulus, Cinnamomom, Cinnamomum aromaticum, Cinnamomum aromaticum Nees, Cinnamomum burmannii, Cinnamomum cassia, Cinnamomum cassia Blume, Cinnamomum cassia J. Presl, Cinnamomum cinnamon, Cinnamomum loureiroi, Cinnamomum mairei Levl., Cinnamomum migao, Cinnamomum obtusifolium, Cinnamomum osmophloeum clones (A and B), Cinnamomum t e r m s osmophloeum Kaneh., Cinnamomum sieboldii, Cinnamomum Cinnamomum osmophloeum Kaneh., Cinnamomum sieboldii, Cinnamomum sieboldii Meissn., Cinnamomum tamala,
  • 23. Background Cinnamon has been used as a spice in several cultures for centuries. It was traditionally used to relieve stomach pain and gas; it is still used for these conditions today. The bark of two cinnamon species (Cinnamomum zeylanicum and Cinnamomum cassia) is used as a spice (cinnamon bark) There is a lack of scientific information to support the use of cinnamon for any condition. However, laboratory studies suggest that cinnamon may be useful in the treatment of diabetes (type 2) due to its blood sugar-lowering effects. Furthermore, cinnamon and its constituents may have anti-inflammatory, antibacterial, antifungal, and antioxidant properties, and it may prove effective in the supportivetreatment of conditions such as cancer or severe virus infections.
  • 24. Uses Based scientific on evidence These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
  • 25. Uses Based scientific on evidence Angina (chest pain) The use of cinnamon for bacterial angina has been reviewed. However, well- designed trials are needed before a firm conclusion can be made. Antioxidant Based human study, a dried aqueous extract of cinnamon (Cinnulin PF®) may improve the antioxidant status of overweight or obese individuals with impaired fasting glucose. More well-designed trials are needed before a firm conclusion can be made.
  • 26. Uses Based scientific on evidence Cinnamon has been granted GRAS (Generally Recognized as Safe) status as a food additive by the U.S. Food and Drug Administration (FDA). GRAS substances are considered safe by the experts and not restricted, as is the case with other food additives.
  • 27. Uses Based scientific on evidence Allergic rhinitis Preliminary evidence suggests that cinnamon may have antiallergic properties. Based on human study, a combination product including Cinnamomum zeylanicum, Malpighia glabra, and Bidens pilosa has demonstrated reduced allergic nasal symptoms in patients with allergic rhinitis. More well-designed trials are needed before a firm conclusion can be made.
  • 28. Uses Based scientific on evidence Bacterial Infection Preliminary study suggests that cinnamon may treat bacterial infections including chronic salmonellosis. However, well-designed trials are needed before a firm conclusion can be made. Candidiasis Preliminary evidence suggests that cinnamon may have activity agains Candida. However, well-designed trials are needed before a firm conclusion can be made.
  • 29. Uses Based scientific on evidence Diabetes Based on human study, cinnamon has been used to control blood sugar; however, results have been mixed in other studies. Further study is needed before a firm conclusion may be made. Eye disorders Preliminary data suggests that a combination herbal eye drop preparation (OphthaCare) may be useful in the treatment of various ophthalmic disorders including: conjunctivitis, conjunctival xerosis (dry eye), acute dacryocystitis, degenerative conditions (pterygium or pinguecula), and disorders in postoperative cataract patients. However, well-designed trials are needed before a firm conclusion can be made.
  • 30. Uses Based scientific on evidence Helicobacter pylori infection Preliminary evidence suggests that cinnamon extracts may be effective against Helicobacter pylori. Based on human study, cinnamon extract was ineffective in ridding of H. pylori. However, the combination of cinnamon with other antimicrobials, or cinnamon extract at a higher concentration, may prove useful. Further well-designed trials are needed before a firm conclusion can be made.
  • 31. Uses Based scientific on evidence Insect repellant Preliminary evidence suggests that cassia oil (Cinnamomum cassia) may reduce dust mites. Based on human study, cinnamon may be useful as a mosquito repellant. However, well-designed trials are needed before a firm conclusion can be made Lung cancer Preliminary study suggests that cinnamon may be useful in the treatment of lung cancer. However, well-designed trials are needed before a firm conclusion can be made.
  • 32. Uses Based scientific on evidence Metabolic syndrome (coronary heart disease) Preliminary study suggests that cinnamon may be useful in the treatment of features of metabolic syndrome in prediabetic subjects. However, well-designed trials are needed before a firm conclusion can be made.
  • 33. Uses based on tradition or theory The below uses are based on tradition or scientific theories. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
  • 34. Uses based on tradition or theory Abdominal pain, abortifacient (induces abortion), abscess, acaricidal (kills mites), acne, Alzheimer’s disease, analgesic (pain reliever), anesthetic, anthelmintic (expels parasitic worms), anticoagulant (stops blood from clotting), antidepressant, anti-inflammatory, antimutagenic, antiparasitic, antiplatelet (interferes with the blood ability to clot), antipyretic (reduces fever), antiseptic, antispasmodic (suppresses spasms), antiviral, arrhythmia, arthritis, asthma, benign prostatic hyperplasia, bloating, blood purification, bronchitis, chronic bronchitis, chronic diarrhea, cognitive function, colds/flu, colic, cough,
  • 35. Uses based on tradition or theory Cystitis (inflammation of urinary bladder), dental caries (cavities), deodorant, dermatitis (inflammation of the skin), diarrhea, digestive aid, digestive disorders, diuretic (increases urination), dyspepsia (indigestion), eczema, emmenagogue (stimulates menstruation), flavoring, food poisoning, food preservation, food uses, gastric ulcer, gastritis (stomach lining inflammation), gout, gum disease, gynecologic disorders, HIV/AIDS, hypercholesterolemia (high cholesterol), hypertension (high blood pressure), hyperthyroid (overactive thyroid gland), immunostimulation (stimulates the immune system),
  • 36. Uses based on tradition or theory Inflammatory conditions, kidney disorders, lice, liver disease, long- term debility, loss of appetite, memory loss, movement disorders, muscle aches, nausea, neuralgia (nerve pain), neuroprotective, premature ejaculation, respiratory tract infection, rheumatoid arthritis, sciatica, sinusitis, skin conditions, snake repellent, sore throat, spermicide, toothache, tumors, urethritis (inflammation of the urethra), urinary disorders, viral infections, weight gain, wound healing.
  • 37. DOSING The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.
  • 38. DOSING Adults (over 18 years old) There are no proven effective medicinal doses for cinnamon. Cinnamon is likely safe when taken by mouth short-term (up to six weeks) in dosages up to 6 grams daily and in amounts commonly found in foods. ~ As an antioxidant, capsules containing 250 milligrams of cinnamon extract (Cinnulin PF®) twice daily for 12 weeks. For candidiasis, eight lozenges of a commercially available cinnamon candy were taken daily for one week; for oral candidiasis, a solution, made by cooking 250 grams of cinnamon in 2000 milliliters of water on medium heat until there was 500 milliliters of solution (solution defined as 50% cinnamon solution) has been used. This solution has been gargled 4-6 times a day and each time with 20-30 milliliters of the solution.
  • 39. DOSING For diabetes, various doses of cinnamon (capsules, powder, extract) have been studied. 1-6 grams of cinnamon daily has been used for up to 90 days. For Helicobacter pylori infection, 80 milligrams of cinnamon extract daily was used for four weeks. For metabolic syndrome, 500 milligrams of a water-soluble cinnamon extract, Cinnulin PF®, is recommended by the manufacturer. As an insect repellant, variousdoses have been studied including a single application of cream containing 5% (w/w) cassia oil (containing 5 grams of cassia oil) for up to 120 minutes.
  • 40. SAFETY Children (under 18 years old) There is no proven safe or effective medicinal dose of cinnamon in children. -------- The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects.
  • 41. Allergies Avoid in individuals with a known allergy or hypersensitivity to cinnamon, its constituents, members of the Lauraceae family, or Balsam of Peru.
  • 42. Side Effects and Warnings Cinnamon is likely safe when taken by mouth short-term. As with any spice or drug, cinnamon can be contaminated by microorganisms during storage. Caution is advised when choosing cinnamon products. Some people may be allergic or sensitive to cinnamon, but this is rare. Skin rash and inflammation, mouth sores, tongue inflammation, gum disease, acne, mouth lesions, and inflammation of the lips have been noted after applying cinnamon (e.g. cinnamon oils, flavored chewing-gums, mints, or toothpastes) on the mouth or face.
  • 43. Side Effects and Warnings Cinnamaldehyde (the chemical compound that gives cinnamon its spice) may cause swelling of the lips,mouth tissue, and the face, hives, skin rash, and mouth sores. Prolonged exposure tocinnamon-flavored gum may cause cancer. Asthma and other breathing difficulties were seen in spice-factory workers. Large amounts of cinnamon may be toxic to the liver due to possible coumarin content. Caution is advised when using other medications that may be hepatotoxic (toxic to the liver).
  • 44. Side Effects and Warnings Although not well studied in humans, large amounts of cinnamon (more than those found in foods) should be avoided in pregnant women due to possible abortion inducing effects. Use cautiously in patients taking drugs that affect the function of the immune system. Use cautiously in patients taking drugs that lower cholesterol. Although not well studied in humans, cinnamon bark may cause decrease in platelet counts in the blood after long-term use. Use cautiously in patients taking drugs, herbs, or supplements broken down by the liver. Use cautiously in patients with liver damage.
  • 45. Side Effects and Warnings Cinnamon may lower blood sugar levels. Use cautiously in patients with diabetes or low blood sugar (hypoglycemia). Cinnamon may enhance the effect of antibiotics.Cinnamon may interact with cardiovascular (heart) agents, due to its several effects on blood and the cardiovascular system (e.g. antiarrhythmic properties). Use cautiously in people with heart conditions
  • 46. Side Effects and Warnings Pregnancy & Breastfeeding Cinnamon is not recommended in medicinal amounts in pregnant or breastfeeding women due to a lack of available scientific evidence Although not well studied in humans, large amounts of cinnamon (more than those found in foods) should be avoided in pregnant women due to possible abortion inducing effects. Cinnamon may act as a spermicide, thereby preventing pregnancy by killing sperm; however, it is not recommended as a form of birth control.
  • 47. INTERACTIONS Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy.
  • 48. INTERACTIONS with Drugs Cinnamon may have antibacterial activity. Use cautiously with antibiotic medications, due to possible additive effects. Cinnamon may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. Patients taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.Cinnamon may increase the risk of bleeding when taken with drugs that increase the riskof bleeding. Some examples include aspirin, anticoagulants (“blood thinners”) such aswarfarin (Coumadin®) or heparin, anti-platelet drugs such as clopidogrel (Plavix®), and non-steroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®). The antifungal properties of cinnamon may enhance the effect of commonly used antifungals. Cinnamon may have antispasmodic effects. Use cautiously if taking other antispasmodics. Cinnamon bark extract may have antiviral effects. Use cautiously if taking antiviral medications, due to possible additive effects. Cinnamon may affect heart rate and thus may interact with heart rate regulating agents.Caution is advised in people taking agents for heart conditions.
  • 49. INTERACTIONS with Drugs Cinnamon may interfere with the way the body processes certain drugs using the liver’s “cytochrome P450” enzyme system. As a result, the levels of drugs in the blood may be altered.Cinnamon may have effects on the immune system. Use cautiously with other agents that alter the immune system. Consult with a qualified healthcare professional, including a pharmacist, to check for interactions.Cinnamon may lower cholesterol. Caution is advised when using medications that may also lower cholesterol.Cinnamon may lower blood pressure. Caution is advised when using medications that may also lower blood pressure. Cinnamon may be toxic to the liver in large amounts due to possible coumarin content. Caution is advised when using other medications that may be hepatotoxic (toxic to the liver). Cinnamon may interact with alcohol, drugs that are used to treat Alzheimer’s disease, analgesics (pain relievers), drugs that decrease inflammation, anti-cancer drugs, anti-obesity drugs, aspirin, dexamethasone, drugs that affect GABA, estrogen, indomethacin, sympathomimetics, terfenadine, or tetracycline.
  • 50. Interactions with Herbs & Dietary Supplements Cinnamon may have antibacterial activity.Use cautiously with antibacterial herbs and supplements, due tpossible additive effects Cinnamon may lower blood sugar levels. Caution is advised in patients with diabetes or hypoglycemia, and in those taking herbs or supplements that affect blood sugar. Serum glucose levels may need to be monitored by a qualified healthcare professional, including a pharmacist, and doses may need adjustment.Cinnamon may increase the risk of bleeding when taken with herbs and supplements that are believed to increase the risk of bleeding. Multiple cases of bleeding have been reported with the use of Ginkgo biloba, and fewer cases with garlic and saw palmetto.The antifungal properties of cinnamon may enhance the effects of commonly used antifungals. Cinnamon bark has been shown to contain very high concentrations of antioxidants.
  • 51. Interactions with Herbs & Dietary Supplements Use cautiously with herbs and supplements that are taken for their antioxidant effects, due to possible additive effects.Cinnamon may have antispasmodic effects. Use cautiously with other antispasmodics.Cinnamomum cassia bark extract may have antiviral effects. Use cautiously with antiviral herbs or supplements, due to possible additive effects. Cinnamon may affect heart rate and thus may interact with heart rate regulating agents.People taking herbs or supplements that alter heart rate should use cinnamon with caution.Cinnamon may interfere with the way the body processes certain herbs or supplements using the liver’s “cytochrome P450” enzyme system. As a result, the levels of other herbsor supplements in the body may be altered.Cinnamon may have effects on the immune system; use cautiously with herbs and supplements with similar effects. Cinnamon may lower cholesterol; use cautiously with herbs and supplements with similar effectsCinnamon may lower blood pressure. Caution is advised when using other herbs or supplements that may also lower blood pressure.Cinnamon may be toxic to the liver in large amounts due to possible coumarin content.
  • 52. Interactions with Herbs & Dietary Supplements Caution is advised when using other herbs or supplements that may be hepatotoxic (toxic to the liver). Cinnamon may interact with herbs or supplements that are used to treat Alzheimer’sdisease, analgesics (pain relievers), herbs or supplements that decrease inflammation, anti-cancer herbs or supplements, anti-obesity herbs or supplements, herbs or supplements that affect GABA , herbs or supplements with hormonal effects, clove, ephedra, or artemisia.
  • 53. References This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to the Natural Standard Research Collaboration www.naturalstandard.com Please see monograph for full references*