Celebrating Hope

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Celebrating Hope

  1. 1. May 8, 2013Brian S. Appleby, M.D.Cleveland Clinic Lou Ruvo Center for Brain Health
  2. 2. Hope vs OptimismHope (verb, noun): “to desire withexpectation of fulfillment”Optimism (noun)/Optimistic (adjective)Celebrate (verb): “to perform publicly”
  3. 3. Trainee: “Why do you do this, youalways have bad news to give?”• Quality vs Quantity of Life (psychiatry)• Comprehensive Model (geriatric psych)• Caregiver/Family dyad (dementia care)• Unmet Need (CJD, young-onset dementia)• 5 days/week (Cleveland Clinic)
  4. 4. -80-60-40-20020Heart Disease Cancer Stroke Lung disease Accidents Diabetes Influenza Alzheimer’s Kidney disease SepticemiaChange in Death Rate (1999 vs 2010) of Top 10 Causes of Death in U.S.A.Does NOT take age into account
  5. 5. #1 Risk for Alzheimer’s?AGEThies W, Alzheimers Dement 2013
  6. 6. Thies W, Alzheimers Dement 2013
  7. 7. Estimated aggregate costs of care by payer forAmericans age 65 years and older withAlzheimer’s disease and other dementias for2013Thies W, Alzheimers Dement 2013
  8. 8. Thies W, Alzheimers Dement 2013
  9. 9. “Im Givin Her All Shes GotCaptain! If I Push It Any Harderthe Whole Things Gonna Blow”
  10. 10. New and Better Disease ModelsAguzzi A, Nature 2009
  11. 11. ABCGoogle searches for “dementia” over time
  12. 12. Appleby BS, Prion 2012U.S. Alzheimer’s Related Publications Over Time
  13. 13. What IS Alzheimer’s Disease?
  14. 14. What is the Best Way to Treat/Prevent Alzheimer’s Disease?LIVE!

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