Introduction to Methods in Neuroscience

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Slides for discussion of Chapter 4 of Cognitive Neuroscience.

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Introduction to Methods in Neuroscience

  1. 1. Figure 5.5 Metabolism of small-molecule and peptide transmitters (Part 2)
  2. 2. Methodologies
  3. 3. Chapter 4
  4. 4. Figure 12-45b Essential Cell Biology (© Garland Science 2010)
  5. 5. Microscopy
  6. 6. Bright field, 400xHematoxylin stained
  7. 7. Bright field, 1000xHematoxylin stained
  8. 8. Fluorescence, 1000xMitoTracker Orange
  9. 9. Fluorescence, 1000xActin-labeled
  10. 10. Fluorescence, 400xActin-labeled + Nucleus-labeled
  11. 11. Fluorescence, 1000xActin-labeled + Nucleus-labeled
  12. 12. Scanning ElectronMicroscope http://commons.wikimedia.org/wiki/ File:Hela_Cells_Image_3709-PH.jpg
  13. 13. Patch Clamping
  14. 14. Figure 10-35 Essential Cell Biology (© Garland Science 2010)
  15. 15. Gene Knockout
  16. 16. Reporter Genes
  17. 17. Figure 10-29a Essential Cell Biology (© Garland Science 2010)
  18. 18. Figure 10-30 Essential Cell Biology (© Garland Science 2010)
  19. 19. Transgenic Animals
  20. 20. Figure 10-36 (part 1 of 2) Essential Cell Biology (© Garland Science 2010)
  21. 21. Figure 10-36 (part 2 of 2) Essential Cell Biology (© Garland Science 2010)
  22. 22. Figure 10-37 Essential Cell Biology (© Garland Science 2010)
  23. 23. Brainbows:Transgenic Mice + Fluorescence Microscopy
  24. 24. Towards Connectomics:Electron Microscopy+ Human and Computer Labor
  25. 25. Computed Tomography(CT or CAT Scan)
  26. 26. Positron EmissionTomography(PET Scan)
  27. 27. Magnetic ResonanceImaging (MRI)
  28. 28. Functional MagneticResonance Imaging (fMRI)
  29. 29. BOLD effect:Blood oxygenation level-dependent effect
  30. 30. ratio ofoxygenatedto deoxygenatedhemoglobin
  31. 31. Transcranial MagneticStimulation (TMS)
  32. 32. fMRI+TMS

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