Gene expression

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Slides for discussion of Essential Cell Biology chapter 7

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Gene expression

  1. 1. Cell & MolecularBiology
  2. 2. Gene Expression
  3. 3. “...the process by whichthe information encodedin a DNA sequenceis translated into a final productthat has some effecton a cell or organism...”
  4. 4. Figure 7-2 Essential Cell Biology (© Garland Science 2010)
  5. 5. Chapter 7
  6. 6. Chapter 3
  7. 7. Transcription
  8. 8. Making RNAfrom DNA
  9. 9. Figure 7-3a,b Essential Cell Biology (© Garland Science 2010)
  10. 10. Figure 7-4 Essential Cell Biology (© Garland Science 2010)
  11. 11. Figure 7- 3c Essential Cell Biology (© Garland Science 2010)
  12. 12. Table 7-1 Essential Cell Biology (© Garland Science 2010)
  13. 13. RNA Polymerase
  14. 14. Reverse Transcriptase
  15. 15. Figure 7-7 Essential Cell Biology (© Garland Science 2010)
  16. 16. Figure 7-8 Essential Cell Biology (© Garland Science 2010)
  17. 17. BacterialTranscription
  18. 18. Figure 7-9 Essential Cell Biology (© Garland Science 2010)
  19. 19. Promotersand Terminators
  20. 20. Figure 7-10 Essential Cell Biology (© Garland Science 2010)
  21. 21. Figure 7-11 Essential Cell Biology (© Garland Science 2010)
  22. 22. 3 kinds of RNA polymeraseGeneral transcription factorsMore complextranscriptional regulationChromatin structure
  23. 23. Table 7-2 Essential Cell Biology (© Garland Science 2010)
  24. 24. GeneralTranscriptionFactors
  25. 25. Figure 7-12 (part 1 of 2) Essential Cell Biology (© Garland Science 2010)
  26. 26. TFIID, TBP andthe TATA Box
  27. 27. Figure 7-13 Essential Cell Biology (© Garland Science 2010)
  28. 28. Figure 7-12 (part 1 of 2) Essential Cell Biology (© Garland Science 2010)
  29. 29. TranscriptionInitiationComplex
  30. 30. Figure 7-12 (part 2 of 2) Essential Cell Biology (© Garland Science 2010)
  31. 31. RNA Processing
  32. 32. Capping andPolyadenylation
  33. 33. Figure 7-16a Essential Cell Biology (© Garland Science 2010)
  34. 34. Figure 7-16b Essential Cell Biology (© Garland Science 2010)
  35. 35. Increase stabilityAid in nuclear exportIdentify RNA as mRNAConfirm both mRNA ends arepresent before translation begins
  36. 36. mRNA Splicing
  37. 37. Introns and Exons
  38. 38. Figure 7-17 Essential Cell Biology (© Garland Science 2010)
  39. 39. Figure 7-23b Essential Cell Biology (© Garland Science 2010)
  40. 40. Figure 7- 23a Essential Cell Biology (© Garland Science 2010)
  41. 41. Figure 7-18 Essential Cell Biology (© Garland Science 2010)
  42. 42. The Spliceosome
  43. 43. Figure 7-19 Essential Cell Biology (© Garland Science 2010)
  44. 44. Figure 7-20 Essential Cell Biology (© Garland Science 2010)
  45. 45. Alternative Splicing
  46. 46. Figure 7-21 Essential Cell Biology (© Garland Science 2010)
  47. 47. NOVA: Cracking the Code of Life
  48. 48. Figure 7-22 Essential Cell Biology (© Garland Science 2010)
  49. 49. Translation
  50. 50. Reverse Transcriptase
  51. 51. Figure 7-24 Essential Cell Biology (© Garland Science 2010)
  52. 52. Reading Frame
  53. 53. Figure 7-25 Essential Cell Biology (© Garland Science 2010)
  54. 54. Transfer RNA (tRNA)
  55. 55. tRNAsecondarystructure
  56. 56. tRNA tertiarystructure
  57. 57. Figure 7-28 Essential Cell Biology (© Garland Science 2010)
  58. 58. tRNA Charging
  59. 59. tRNA Synthetase
  60. 60. Movie 7.6
  61. 61. Figure 7-29 (part 1 of 2) Essential Cell Biology (© Garland Science 2010)
  62. 62. Figure 7-29 (part 2 of 2) Essential Cell Biology (© Garland Science 2010)
  63. 63. Wobble base pairing
  64. 64. The Ribosome
  65. 65. Reverse Transcriptase
  66. 66. Figure 7-32 Essential Cell Biology (© Garland Science 2010)
  67. 67. Figure 7-31 Essential Cell Biology (© Garland Science 2010)
  68. 68. 2/3 RNA1/3 ProteinRibozyme
  69. 69. Figure 7-34 Essential Cell Biology (© Garland Science 2010)
  70. 70. Figure 7-30 Essential Cell Biology (© Garland Science 2010)
  71. 71. Initiation
  72. 72. Figure 7-35 (part 1 of 5) Essential Cell Biology (© Garland Science 2010)
  73. 73. Figure 7-35 (part 2 of 5) Essential Cell Biology (© Garland Science 2010)
  74. 74. Figure 7-35 (part 3 of 5) Essential Cell Biology (© Garland Science 2010)
  75. 75. Figure 7-35 (part 4 of 5) Essential Cell Biology (© Garland Science 2010)
  76. 76. Figure 7-35 (part 5 of 5) Essential Cell Biology (© Garland Science 2010)
  77. 77. Elongation
  78. 78. Figure 7-33 (part 1 of 5) Essential Cell Biology (© Garland Science 2010)
  79. 79. Figure 7-33 (part 5 of 5) Essential Cell Biology (© Garland Science 2010)
  80. 80. Figure 7-33 (part 2 of 5) Essential Cell Biology (© Garland Science 2010)
  81. 81. Figure 7-33 (part 3 of 5) Essential Cell Biology (© Garland Science 2010)
  82. 82. Figure 7-33 (part 4 of 5) Essential Cell Biology (© Garland Science 2010)
  83. 83. Peptidyl Transferase(aminoacyltransferase)
  84. 84. Figure 4-1 Essential Cell Biology (© Garland Science 2010)
  85. 85. Reverse Transcriptase
  86. 86. Figure 7-29 (part 2 of 2) Essential Cell Biology (© Garland Science 2010)
  87. 87. Movies 7.8, 7.9
  88. 88. Termination
  89. 89. Figure 7-37 (part 1 of 3) Essential Cell Biology (© Garland Science 2010)
  90. 90. Figure 7-37 (part 2 of 3) Essential Cell Biology (© Garland Science 2010)
  91. 91. Figure 7-37 (part 3 of 3) Essential Cell Biology (© Garland Science 2010)
  92. 92. Polyribosomes
  93. 93. Figure 7-38a Essential Cell Biology (© Garland Science 2010)
  94. 94. Figure 7-38b Essential Cell Biology (© Garland Science 2010)
  95. 95. Figure 7-40 (part 1 of 2) Essential Cell Biology (© Garland Science 2010)
  96. 96. Figure 7-40 (part 2 of 2) Essential Cell Biology (© Garland Science 2010)
  97. 97. Figure 7-41 Essential Cell Biology (© Garland Science 2010)
  98. 98. PosttranslationalModification
  99. 99. Protein Precursors,or Pro-proteins
  100. 100. Figure 7-41 Essential Cell Biology (© Garland Science 2010)
  101. 101. Protein Splicing
  102. 102. Protein Degradation

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