Bioinformatics

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Bioinformatics

  1. 1. Created By: ANKIT UPADHYAYA BIOINFORMATICS
  2. 2. INTRODUCATION
  3. 3. WHAT IS BIOINFORMATICS??
  4. 5. AIM OF BIOINFORMATICS
  5. 7. USEFUL DATABASE ON BIOINFORMATICS
  6. 8. BIOLOGICAL DATABASES
  7. 9. BIOLOGICAL DATABASES: WHY? <ul><li>Need for storing and communicating large datasets has grown </li></ul><ul><li>Make biological data available to scientists. </li></ul><ul><li>To make biological data available in computer-readable form. </li></ul>02/26/11 14:28
  8. 10. DIFFERENT CLASSIFICATIONS OF DATABASES <ul><li>Type of data </li></ul><ul><ul><li>nucleotide sequences </li></ul></ul><ul><ul><li>protein sequences </li></ul></ul><ul><ul><li>proteins sequence patterns or motifs </li></ul></ul><ul><ul><li>macromolecular 3D structure </li></ul></ul><ul><ul><li>gene expression data </li></ul></ul><ul><ul><li>metabolic pathways </li></ul></ul>02/26/11 14:28
  9. 11. DIFFERENT CLASSIFICATIONS OF DATABASES…. <ul><li>Primary or derived databases </li></ul><ul><ul><li>Primary databases: experimental results directly into database </li></ul></ul><ul><ul><li>Secondary databases: results of analysis of primary databases </li></ul></ul><ul><ul><li>Aggregate of many databases </li></ul></ul><ul><ul><ul><li>Links to other data items </li></ul></ul></ul><ul><ul><ul><li>Combination of data </li></ul></ul></ul><ul><ul><ul><li>Consolidation of data </li></ul></ul></ul>02/26/11 14:28
  10. 12. DIFFERENT CLASSIFICATIONS OF DATABASES…. <ul><li>Technical design </li></ul><ul><ul><li>Flat-files </li></ul></ul><ul><ul><li>Relational database (SQL) </li></ul></ul><ul><ul><li>Exchange/publication technologies (FTP, HTML, CORBA, XML,...) </li></ul></ul>02/26/11 14:28
  11. 13. DIFFERENT CLASSIFICATIONS OF DATABASES…. <ul><li>Availability </li></ul><ul><ul><li>Publicly available, no restrictions </li></ul></ul><ul><ul><li>Available, but with copyright </li></ul></ul><ul><ul><li>Accessible, but not downloadable </li></ul></ul><ul><ul><li>Academic, but not freely available </li></ul></ul><ul><ul><li>Proprietary, commercial; possibly free for academics </li></ul></ul>02/26/11 14:28
  12. 14. NUCLEOTIDE SEQUENCE DATABASES
  13. 15. PROTEIN SEQUENCE DATABSES
  14. 16. STRUCTURAL DATABASES
  15. 17. GENBANK (WEBSITE::HTTP://WWW.NCBI.NLM.NIH.GOV/GENBANK)
  16. 18. EMBL (WEBSITE::HTTP://WWW.EBI.AC.UK/EMBL/)
  17. 19. DDBJ (WEBSITE::HTTP://WWW.DDBJ.NIG.AC.JP)
  18. 20. APPLICATION
  19. 23. DEFINITIONS

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