1CD Celiac Disease Angelica Valdes Course: MGT220 Carrington College Instructor: Mr. Sayers Date: 03/19/2013
2CD Introduction Celiac disease is an inherited inflammatory autoimmune disease which affects the villi ofthe small intestines, and is triggered by gluten, a protein found in wheat, barley and rye. Withsymptoms that vary from person to person, it’s a disease that often remains undiagnosed. It’sestimated that 2 to 3 million people in the U.S. alone may have this disease, and about 80% arenot yet diagnosed; most people don’t know that they may have this disease. This disease canaffect all ages from the very young to the elderly, genetic susceptible individuals. The Villi are finger like projections that move back and forth (like a Wave) to help in themovement and digestion of foods; as food passes through the small intestines nutrients andvitamins that the body needs are extracted. What happens in severe cases; these Villi becomeeroded, until nothing is left but a smooth surface which cannot function, causing the body to losea lot of needed nutrients and vitamins. In mild cases there may be just a few patches; you mayfeel sick after ingesting food containing gluten, and once you stop eating the gluten by-productyou start to feel better. Newborns aren’t born with CD, but if one parent has it then precautions have to be taken withthe infant. Breast feeding will give the new infant antibodies and immunities that are needed forthe infant. Tests can be done for the infants. And at age 2 and above they will be tested with theadults’ test; (IgA TTG) every 2 yrs.
3CD CausesThere are three proteins by-products which may contain of have some sort the dietary grainwhich can be causing the problem, they are as follows: 1. Wheat-scientific name: Gliadins and Glutenins 2. Rye-scientific name: Secalins 3. Barley-scientific name: Hordeins The first 2 combined will activate the celiac disease. These last two may not contribute to thedisease, if it does it maybe just a very small amount. People will mistake the symptoms for foodallergies; unfortunately this is not the case. Symptoms There is a large spectrum of the gastrointestinal tract symptoms; and they are as follows: 1. Chronic Diarrhea; 2. Distended belly; 3. Cramping and pain; 4. Weight loss; 5. Loss of appetite or a voracious appetite; 6. Vomiting; 7. Stool may be bulky, pale or foul;
4CD Tests There are actually 2 tests that are done to find out if indeed you have Celica. The first test isa Blood test (IgA tissue tranglutaminase antibody or for short (IgA TTG), “Anti-transglutaminase antibodies (ATA) are autoantibodies against the transglutaminase protein.Antibodies serve an important role in the immune system by detecting cells and substances thatthe rest of the immune system then eliminates. These cells and substance can be foreign (forexample, viruses) and also can be produced by the body (for example, cancer cells). Antibodiesagainst the body’s own products are called autoantibodies. Autoantibodies can sometimeserrantly be directed against healthy portions of the organism, causing autoimmune diseases.” Ifthis test is positive, the next step to be performed is a small intestinal mucosal biopsy. Small Intestinal Mucosal Biopsy is quite a simple procedure and can be completed within onehour. The patient will be given a topical anesthetic to the back of the throat. A capsule and tubeare introduced, the patient is asked to swallow. The capsule contains a small camera with acutting edge. Once the capsule reaches its destination a small sample of intestine tissue isobtained. This tissue is then checked under a microscope, for tissue damage. If this test ispositive then the next step is diet changes. That’s where you will have to work with anutritionist, as well as your doctor, to help you get control of this disease.
5CD TreatmentPeople with celiac disease who eat gluten have higher than normal levels of certain antibodies intheir blood. Antibodies are produced by the immune system in response to substances that thebody perceives to be threatening. People with this disease need to stay totally away from Glutenand Gluten by-products, as well as all over the counter medication that use /or contains gluten.Sticking to this special diet people can have a low intake of Iron; Folic Acid; B-vitamin andfiber. Eating beans is a good source of replenishing these nutrients and vitamins. But eat beansin moderation due to the gastrointestinal discomfort, which can mimic symptoms of Celica. Alsoit is recommended to take calcium, vitamin-D, and a multivitamin. Prognosis There is no cure for Celiac, but with proper diet and vitamins it can be controlled. Can befatal if not detected and treated. In time the damaged Villi can be repaired. But as soon as youintroduce gluten to your body the problem will return. Conclusion It’s hereditary: Unknown Etiology. It’s very important that you stick with the special glutenfree diet. You need to read and check all food and product labels such as lotions, lipstick or lipbalm, these are bi-products that can carry gluten and should not be used. There are books andagencies that strictly deal with Celiac disease, but make sure you research the material. Becausethere’s information out there that is not giving you the whole view of the disease. When in doubt
6CDask your doctor and or nutritionist. There’s a long list of foods and by-products which maycontain gluten, one important factor is breads, and bread by-products (the elasticity which bindsthe bread together). National support groups: Celiac Disease Foundation (CDF) Raising our Celiac Kids (R.O.C.K.) Celica Sprue Association
7CD References:Health Line: Mucosal Biopsy: or small intestine biopsy. Janis O. Flores. The gale Group, Inc.Gale Encyclopedia of Medicine 2002.Kimberly Newton M.D. Pediatric gastroenterologist—discussing the children aspect of thisdisease and what can be done.Martin Kagnoff M.D. One of the countries’ leading authorities of Celiac Disease.Shawn McNally M.P.H. RD---discussing the disease and misconceptions along with the diets doand don’ts.Wikipedia: Article on Anti Transglutaminase antibody. Edited by Diptanshu D. Dec. 26, 2012.Wm. K. Warren Medical Research Center for Celiac Disease at UCSD. Seminar January 6,2011.