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Owing to the generosity of Sir WJ Thomas an Institute of
 Preventive Medicine was built in 1921 for the Department of
     Public Health and the School of Preventive Medicine.
Sir William Osler:
                                                            “
I think we can look forward with
         hope to the inauguration of a really great
          School of Preventive Medicine…that will
         be an example to the world….
          …The Professor must have a burning
          enthusiasm for research.”
Professor Edgar L Collis
Inaugral Lecture: ‘Finem Respice’ Lancet 1920;i:6-11


   •  ‘The task to be accomplished:
     ‘What is then the task which lies before the Welsh National
     School of Medicine. It has to train a whole and complete
     medical service for the Principality so that there may be
     established throughout Wales a capable and well-equipped
     band of apostles preaching the gospel of health on hill and
     dale, in hamlet, village and town.’

      ‘I am undertaking a heavy responsibility in that I am the first
      occupant of the only chair in the country devoted entirely to
      the subject of preventive medicine. There is no tradition to
      guide, no precedent to refer to…’
“… I mean the prevention of disease. This side presents a
point of view which centres thought on the positive entity,
Health, rather than on the varied manifestations of lack of
health which we sum up in the negative term, disease…
but each member of the community is only interested in
these matters in a half -hearted way… ”
Research
EL Collis again… Inaugral Lecture: ‘Finem Respice’
 ‘The Institute stands not only for teaching, but also research
 and the spirit of research….The Institute must be
 acquainted with the health conditions of Wales and be
 prepared to direct research to meet the needs of the
 Welsh nation; it must have knowledge of social
 conditions with which health is so intimately associated; …
 it must note variations in sickness and mortality in
 different districts and be prepared to assist in searching out
 the causes and finding ways to remove them…. Its scope
 must, as far as medicine is concerned, be broad… and
 claim all knowledge for its own.’
1919 First Professor of Preventive Medicine appointed
1921 Institute of Preventive Medicine opened
1925: Stevens Committee of Enquiry

 “You have got these fancy departments
                                 these men are
 (Preventive Medicine and Tuberculosis)…
 running your place and they have more to
 say that the men who are doing the real work
 of the hospital… they are luxuries”

 Referring to the Institute of Preventive Medicine….
 “…the block will be exceedingly useful for
 other work”
out of
AL Cochrane 1909-1988


…the spirit of research…
World Health Organisation and English
     Department of Health fund work at National
1978 Perinatal Epidemiology Unit, Oxford, UK to
     assemble a register of controlled trials in
     perinatal medicine

       Outline plans drafted in Cardiff, Wales, UK for
1976   systematic reviews of controlled trials in
       perinatal medicine

       Identification of controlled trials in perinatal
1974
       medicine begins in Cardiff, Wales, UK

       Publication of Archie Cochrane's '
       Effectiveness and Efficiency: random reflections
1972   on health services' , which drew attention to our
       collective ignorance about the effects of health
       care
2000 UK Parliament Health Committee
Press Notice No. 13 of Session 2000-01, dated 27 March 2000

  "Public health" is not a term understood by the majority
  of the public. It can be variously defined so as to cover
  trends of disease in a population, the provision of
  preventive and health improving care, or a range of
  health-impacting factors including or excluding the NHS.
  In a key note speech delivered as the annual LSE health
  lecture on 8 March 2000, the Secretary of State for
  Health himself drew attention to the problems in
  defining public health and the implications of those
  problems and said:
  "The time has come to take public health out of
  the ghetto."
House of Commons Select Committee
  on Health: Second Report, 2001
       Leadership in Public Health

para We agree with the Secretary of State that
102 health authorities are not solely responsible
     for improving health, however we consider
             that the strategic lead for public health must be
     clarified. The “plethora of partnerships”
     make it vital that there is clear strategic of
     public health at a local level. Whatever
     arrangements are made, leadership should be
     strong, explicit and should have clear lines of
     accountability.
April
        Public Health Group registered
2008



Mar
        Chinese Cochrane Centre registered
1999



Nov     Sexually Transmitted Diseases Group
1998    registered
Mar
        HIV/AIDS Group registered
1998
The Spirit of Public Health Research in Wales

•     a collaborative model

     ▫  draw together researchers from health sciences, sociology,
        psychology, engineering, architecture, economics and
        business studies, geography, informatics and others.

•     Build on the successes and strengths of health research in Wales

•     Take new opportunities, new partnerships (eg ONS now in Wales),
      new technology for record linking large routine health datasets for
      public health studies of the whole Welsh population Wales).

     ▫     (HIRU/SAIL) and multi-sectoral datasets (WISERD) and
          Web based epidemiology.
Designed for Life
•  A New Policy Context
•  The vision which drives this renewal is shaped by the paradigm
   embraced in the Welsh Assembly Government’s constitution -
   Sustainable Development.

•  “We remain one of the few administrations in the world to have
   such a statutory duty, and it gives us an opportunity to develop
   Wales, as a small, smart nation, in ways which contribute
   sustainably to people’s economic, social and environmental
   wellbeing, now and in the future”

•  “the central organising principle of public service – because public
   service must be about achieving benefits for the whole of society
   and for the long term.”
Sustainable Communities
– a new paradigm for Public Health!

                        “I want a Wales fit for generations
                        to come …
                        What motivates me is doing my
                        very best to ensure a brighter,
                        sustainable future for [my
                        grandchildren and their
                        grandchildren] and every other
                        child growing up in Wales today …
                        [Therefore], top of the list … of our
                        priorities which will continue to
                        improve the quality of life for
                        people today and in the future …
                        is sustainability”

                        First Minister, 8 February 2008
Implications of “Sustainable Communities”




 Social                    This and
 Economic   Environments   Future
 Natural                   Generations
Preliminary Analysis - Smoking
 SMOKING STATUS                     CASES %        CONTROLS
                                    (n)            % (n)
 Smoked            YES                 76.9 (70)    48.8 (106)
 before            NO                  23.1 (21)    51.2 (111)
 Pregnancy
 Smoked            YES                70.3 (64)     44.2 (96)
 during first      NO                  29.7 (27)    55.8 (121)
 12weeks
Unadjusted Odds Ratios (95%Confidence Intervals).

Smoking before pregnancy : 3.3 (1.82, 6.05)
Smoking during first trimester: 2.8 (1.63, 4.98)
Preliminary Results: Alcohol
ALCOHOL CONSUMPTION                  CASE % (n)         CONTROL% (n)
Typical number of     0              22.2 (20)          38.6 (83)
units per week in     < 14           48.9 (44)          51.2 (110)
first trimester
                      >14            28.9 (26)          10.2 (22)
Binge drinker (> 6    Yes            51.6 (47)          37.0 (80)
units in one sitting/ No             47.3 (43)          62.0 (134)
day)
                      Don’t know     1.1 (1)            0.9 (2)



 Unadjusted Odds Ratio (95%CI)
 < 14 units per week: 1.6 (0.83, 2.95)
 > 14 units per week: 4.7 (2.07, 10.71)
 Binge Drinking: > 6 units in one sitting/day: 1.8 (1.00, 2.97)
Preliminary Analysis:
        Recreational Drug use
DRUG USE STATUS                      CASES% (n)          CONTROLS%
                                                         (n)
Ever used illegal         YES            48.4 (44)           30.9 (67)
substances                No             51.6 (47)          69.1 (150)
Used prior to          YES               20.9 (19)           7.4 (16)
knowledge of pregnancy No                79.1 (72)          92.6 (201)
Used during first 12      YES             15.4 (14)           5.1 (11)
weeks of pregnancy        NO             84.6 (77)          94.9 (206)
 Unadjusted Odds Ratios (95%Confidence Intervals)
 Ever used illegal substances: 2.0 (1.15, 3.35)
 Used illegal substances before pregnancy: 2.9 (1.39, 6.19)
 Used illegal substances during first trimester: 2.7 (1.17, 6.29)
Towards Evidence Based Public Health


 RESEARCH                  EVIDENCE      PUBLIC



 Evaluation              Assessment      Political
                                         Process
Surveillance              Synthesis



IMPLEMENTATION             POLICY       LEGISLATION
RCT Results: 74 intervention homes versus 72 control homes
• Improvement in breathing at 6 mths 52% v 2%
• Reduction in medication at 6 mths       41% v -17%
• Reduction in wheeze affecting act’      31% v 7%
The proposed functions of the “Institute”

•  Evidence Centre
•  Coordinate public health knowledge management.

•  Identify knowledge gaps and develop research priorities.

•  Provide a strategic link between academic public health researchers,
   PHW, WAG, NHS and LAs.

•  Manage the Wales public health research programme and stimulate
   and where appropriate coordinate multicentre and multidisciplinary
   research, especially exploiting natural experiments.

•  Drive the timely use of national datasets and surveillance systems
   for maximum public health gain, possibly embracing the Wales
   Observatory.

•  Promote and coordinate use of public health and mathematical
   modelling to assist decision making.
The proposed functions of the “Institute”

•  Public Health Training
•  managing the all Wales public health training
   programme under the direction of the Postgraduate
   Dean.
•  Liaison with academic training centres such as Cardiff
   University MPH Programme and UWIC/HPA
   International training Centre for Chemical Hazards.

•  Policy and Programmes “Laboratory”
•  Create an evidence-policy “space” which would be a
   forum for debate and development of advice.

•  Test new ideas for new prevention policies, programmes
   and projects.
The Spirit of Public Health Research in Wales

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The Spirit of Public Health Research in Wales

  • 1. Owing to the generosity of Sir WJ Thomas an Institute of Preventive Medicine was built in 1921 for the Department of Public Health and the School of Preventive Medicine. Sir William Osler: “ I think we can look forward with hope to the inauguration of a really great School of Preventive Medicine…that will be an example to the world…. …The Professor must have a burning enthusiasm for research.”
  • 2.
  • 3. Professor Edgar L Collis Inaugral Lecture: ‘Finem Respice’ Lancet 1920;i:6-11 •  ‘The task to be accomplished: ‘What is then the task which lies before the Welsh National School of Medicine. It has to train a whole and complete medical service for the Principality so that there may be established throughout Wales a capable and well-equipped band of apostles preaching the gospel of health on hill and dale, in hamlet, village and town.’ ‘I am undertaking a heavy responsibility in that I am the first occupant of the only chair in the country devoted entirely to the subject of preventive medicine. There is no tradition to guide, no precedent to refer to…’
  • 4. “… I mean the prevention of disease. This side presents a point of view which centres thought on the positive entity, Health, rather than on the varied manifestations of lack of health which we sum up in the negative term, disease… but each member of the community is only interested in these matters in a half -hearted way… ”
  • 5. Research EL Collis again… Inaugral Lecture: ‘Finem Respice’ ‘The Institute stands not only for teaching, but also research and the spirit of research….The Institute must be acquainted with the health conditions of Wales and be prepared to direct research to meet the needs of the Welsh nation; it must have knowledge of social conditions with which health is so intimately associated; … it must note variations in sickness and mortality in different districts and be prepared to assist in searching out the causes and finding ways to remove them…. Its scope must, as far as medicine is concerned, be broad… and claim all knowledge for its own.’
  • 6. 1919 First Professor of Preventive Medicine appointed 1921 Institute of Preventive Medicine opened 1925: Stevens Committee of Enquiry “You have got these fancy departments these men are (Preventive Medicine and Tuberculosis)… running your place and they have more to say that the men who are doing the real work of the hospital… they are luxuries” Referring to the Institute of Preventive Medicine…. “…the block will be exceedingly useful for other work”
  • 8. AL Cochrane 1909-1988 …the spirit of research…
  • 9.
  • 10. World Health Organisation and English Department of Health fund work at National 1978 Perinatal Epidemiology Unit, Oxford, UK to assemble a register of controlled trials in perinatal medicine Outline plans drafted in Cardiff, Wales, UK for 1976 systematic reviews of controlled trials in perinatal medicine Identification of controlled trials in perinatal 1974 medicine begins in Cardiff, Wales, UK Publication of Archie Cochrane's ' Effectiveness and Efficiency: random reflections 1972 on health services' , which drew attention to our collective ignorance about the effects of health care
  • 11. 2000 UK Parliament Health Committee Press Notice No. 13 of Session 2000-01, dated 27 March 2000 "Public health" is not a term understood by the majority of the public. It can be variously defined so as to cover trends of disease in a population, the provision of preventive and health improving care, or a range of health-impacting factors including or excluding the NHS. In a key note speech delivered as the annual LSE health lecture on 8 March 2000, the Secretary of State for Health himself drew attention to the problems in defining public health and the implications of those problems and said: "The time has come to take public health out of the ghetto."
  • 12. House of Commons Select Committee on Health: Second Report, 2001 Leadership in Public Health para We agree with the Secretary of State that 102 health authorities are not solely responsible for improving health, however we consider that the strategic lead for public health must be clarified. The “plethora of partnerships” make it vital that there is clear strategic of public health at a local level. Whatever arrangements are made, leadership should be strong, explicit and should have clear lines of accountability.
  • 13. April Public Health Group registered 2008 Mar Chinese Cochrane Centre registered 1999 Nov Sexually Transmitted Diseases Group 1998 registered Mar HIV/AIDS Group registered 1998
  • 14. The Spirit of Public Health Research in Wales •  a collaborative model ▫  draw together researchers from health sciences, sociology, psychology, engineering, architecture, economics and business studies, geography, informatics and others. •  Build on the successes and strengths of health research in Wales •  Take new opportunities, new partnerships (eg ONS now in Wales), new technology for record linking large routine health datasets for public health studies of the whole Welsh population Wales). ▫  (HIRU/SAIL) and multi-sectoral datasets (WISERD) and Web based epidemiology.
  • 15. Designed for Life •  A New Policy Context •  The vision which drives this renewal is shaped by the paradigm embraced in the Welsh Assembly Government’s constitution - Sustainable Development. •  “We remain one of the few administrations in the world to have such a statutory duty, and it gives us an opportunity to develop Wales, as a small, smart nation, in ways which contribute sustainably to people’s economic, social and environmental wellbeing, now and in the future” •  “the central organising principle of public service – because public service must be about achieving benefits for the whole of society and for the long term.”
  • 16. Sustainable Communities – a new paradigm for Public Health! “I want a Wales fit for generations to come … What motivates me is doing my very best to ensure a brighter, sustainable future for [my grandchildren and their grandchildren] and every other child growing up in Wales today … [Therefore], top of the list … of our priorities which will continue to improve the quality of life for people today and in the future … is sustainability” First Minister, 8 February 2008
  • 17. Implications of “Sustainable Communities” Social This and Economic Environments Future Natural Generations
  • 18. Preliminary Analysis - Smoking SMOKING STATUS CASES % CONTROLS (n) % (n) Smoked YES 76.9 (70) 48.8 (106) before NO 23.1 (21) 51.2 (111) Pregnancy Smoked YES 70.3 (64) 44.2 (96) during first NO 29.7 (27) 55.8 (121) 12weeks Unadjusted Odds Ratios (95%Confidence Intervals). Smoking before pregnancy : 3.3 (1.82, 6.05) Smoking during first trimester: 2.8 (1.63, 4.98)
  • 19. Preliminary Results: Alcohol ALCOHOL CONSUMPTION CASE % (n) CONTROL% (n) Typical number of 0 22.2 (20) 38.6 (83) units per week in < 14 48.9 (44) 51.2 (110) first trimester >14 28.9 (26) 10.2 (22) Binge drinker (> 6 Yes 51.6 (47) 37.0 (80) units in one sitting/ No 47.3 (43) 62.0 (134) day) Don’t know 1.1 (1) 0.9 (2) Unadjusted Odds Ratio (95%CI) < 14 units per week: 1.6 (0.83, 2.95) > 14 units per week: 4.7 (2.07, 10.71) Binge Drinking: > 6 units in one sitting/day: 1.8 (1.00, 2.97)
  • 20. Preliminary Analysis: Recreational Drug use DRUG USE STATUS CASES% (n) CONTROLS% (n) Ever used illegal YES 48.4 (44) 30.9 (67) substances No 51.6 (47) 69.1 (150) Used prior to YES 20.9 (19) 7.4 (16) knowledge of pregnancy No 79.1 (72) 92.6 (201) Used during first 12 YES 15.4 (14) 5.1 (11) weeks of pregnancy NO 84.6 (77) 94.9 (206) Unadjusted Odds Ratios (95%Confidence Intervals) Ever used illegal substances: 2.0 (1.15, 3.35) Used illegal substances before pregnancy: 2.9 (1.39, 6.19) Used illegal substances during first trimester: 2.7 (1.17, 6.29)
  • 21.
  • 22.
  • 23.
  • 24.
  • 25. Towards Evidence Based Public Health RESEARCH EVIDENCE PUBLIC Evaluation Assessment Political Process Surveillance Synthesis IMPLEMENTATION POLICY LEGISLATION
  • 26. RCT Results: 74 intervention homes versus 72 control homes • Improvement in breathing at 6 mths 52% v 2% • Reduction in medication at 6 mths 41% v -17% • Reduction in wheeze affecting act’ 31% v 7%
  • 27. The proposed functions of the “Institute” •  Evidence Centre •  Coordinate public health knowledge management. •  Identify knowledge gaps and develop research priorities. •  Provide a strategic link between academic public health researchers, PHW, WAG, NHS and LAs. •  Manage the Wales public health research programme and stimulate and where appropriate coordinate multicentre and multidisciplinary research, especially exploiting natural experiments. •  Drive the timely use of national datasets and surveillance systems for maximum public health gain, possibly embracing the Wales Observatory. •  Promote and coordinate use of public health and mathematical modelling to assist decision making.
  • 28. The proposed functions of the “Institute” •  Public Health Training •  managing the all Wales public health training programme under the direction of the Postgraduate Dean. •  Liaison with academic training centres such as Cardiff University MPH Programme and UWIC/HPA International training Centre for Chemical Hazards. •  Policy and Programmes “Laboratory” •  Create an evidence-policy “space” which would be a forum for debate and development of advice. •  Test new ideas for new prevention policies, programmes and projects.