Research design & conduct service
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Research design & conduct service



The Research Design & Conduct Service recently gave a presentation to staff at the Cardiff School of Medicine to let people know about their services, advice and support, which they offer to health ...

The Research Design & Conduct Service recently gave a presentation to staff at the Cardiff School of Medicine to let people know about their services, advice and support, which they offer to health professionals who are in the process of developing research projects. The RDCS was funded in 2010 by the National Institute for Social Care and Health Research (NISCHR), part of the Welsh Assembly Government. Their partner organisations are Cardiff and Vale University HB, Cwm Taf HB, Aneurin Bevan HB and Powys Teaching HB.

Learn more about the RDCS by viewing the presentation below and by visiting their website:



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    Research design & conduct service Research design & conduct service Presentation Transcript

    • NIHR Primary Care Interven1ons call •    Broad defini1on of Primary Care  –  “health care interven1ons or services delivered in primary care  se=ngs”. •  Pa1ent involvement is important •  Par1cularly interested in applica1ons that address:  –  the management of long‐term condi1ons, the management of  mul1ple morbidity or  –  interven1ons that prevent acute admission to hospital  –  the effec1veness of exis1ng or new interven1ons  –  the benefits of new approaches to the delivery of services  –  mul1ple health related behaviours   
    • 4 eligible funding streams •  Efficacy and Mechanism Evalua1on (EME) •  Health Services and Delivery Research  (HS&DR) •  Health Technology Assessment (HTA) •  Public Health Research (PHR) 
    • Efficacy and Mechanism   Evalua1on (EME)   •  must evaluate the efficacy of an interven1on  and may also include the evalua1on of  mechanisms. •  The main clinical study must account for the  majority of the costs  •  may also include  –   ini1al stages  –  development of an interven1on  –  pilot/feasibility studies 
    • Health Services and Delivery  Research (HS&DR) •  research on different models of service  delivery and pa1ent experience  –  new staff roles  –  compara1ve models of care  –  pa1ent‐centred care  –  changes in health systems  –  organisa1onal studies 
    • Health Technology Assessment  (HTA) •  evalua1ons of the clinical and cost  effec1veness of interven1ons for the   –  diagnosis  –  management  –  monitoring  –  treatment or rehabilita1on of pa1ents 
    • Public Health Research (PHR) •  non‐NHS public health interven1ons intended  to improve the health of the public and  reduce inequali1es in health.  •  Seeking applica1ons looking at the role of  primary care prac11oners in health promo1on  or health protec1on work outside health  service se=ngs.  
    • Funding stream   EME   HS&DR   HTA   PHR  Pre‐clinical   No   No   No   No  Feasibility   Yes   Yes   Yes   Yes  Pilot   Yes   Yes   Yes   Yes  Phase I   No   Maybe   No   No  Phase II   Yes   Maybe  No   No  Phase III   Yes   Maybe   Yes   Yes  Phase IV   No   Maybe   Yes   Yes  Scoping   Yes   Yes   Yes   Yes  Diagnos1c   Yes   Maybe   Yes   No  Systema1c review   No   Yes   Yes   Yes  
    • Timings  •  Call opening Thursday last week •  Ends 22nd March •  Funding decisions March 2014 •  h^p:// 
    • Sta1s1cally significant? 
    • Sta1s1cally significant 
    • Sta1s1cally discernible •  more accurate •  s1ll understandable •  avoids confusion between clinical importance 
    • Research Design & Conduct Service (RDCS) Dr Mark Kelly 
    • RDCS  Funded by NISCHR to  formalise exis1ng research  rela1onships with healthcare  professionals  Covering HBs in    SE Wales  Consultancy to healthcare  professionals for funding  applica1ons 
    • RDCS advises on ... •  focusing ideas and refining the research  ques1on(s) •  building an appropriate research team •  involving pa1ents and carers •  choice and applica1on of research methodologies  for both qualita1ve and quan1ta1ve approaches •  iden1fying the resources required for a  successful project including iden1fying suitable  funding opportuni1es 
    • The service aims to provide users with: •  advice and support on all aspects of funding  applica1ons •  links to experienced researchers for partner  organisa1ons •  Successful funding bids! 
    • RDCS team Mirella Longo Dr Kirsten McEwanHealth Economist Psychology/StatisticsDr Claire O’ NeillQualitative research Dr Mark Kelly StatisticsVicky RobertsResearchadministrator
    • How the service operates NHS  worker thinks of a  They email their R&D  They email  research idea  office Consultant contacts NHS  Logged in system ‐ researcher  and provides  Request  passed onto  request for support  RDCS consultant  support  form returned  Funding applica1on  submi^ed (RDCS role  Researcher provides  feedback on outcome  ends) 
    • How the service operates •  help desks •  presenta1ons and a^end  conferences •  hos1ng events specifically linked  to funding calls •  newsle^er/website 
    • Progress •  To date we have advised on 105 projects •  We have supported 15 Research for Public  and Pa1ent Benefit funding bids •  All supported studies got through the first  stage of RfPPB 
    • •  PATCH Art Therapy & Post‐natal  •  A feasibility study of an interven1on to  Depression      improve the care of pa1ents with •  Topical vs oral gabapen1n for peripheral  tuberous sclerosis in Wales    diabe1c neuropathy    •  Point‐of‐care tests to assist an1bio1c •  PLEAD   prescribing decisions for diabe1c foot •  Phase 2 detox interven1on in prisoners on  ulcer infec1ons  remand for alcohol abuse    (INDUCE pilot study)   •  EDDY ‐ Early Detec1on of type 1 Diabetes  •  A feasibility study to inform design of a  in Youth    defini1ve pragma1c randomised  controlled trial to evaluate effec1veness •  RCT crossover trial of prostaglandin  and cost‐effec1veness of different  F2alpha in thyroid eye disease     methods of providing BRCA1/2 predic1ve •  OPTIC: Op1mising Consent Processes in  test results.   Trials in Cri1cal Care    •  PROMiSE NHS: Pa1ent Reported Outcome •  Rehabilita1on programme to support ill  Measures in Service Evalua1on: A pilot  military veterans achieve op1mal health  study for radical change management in  and well‐being ‐ Phase 2 randomised  the NHS    controlled trial  •  Func1onal Assessments for People with •  Final development and field tes1ng of  Hun1ngton’s Disease    scripted consulta1ons for human  •  Uptake Promo1on for Long Ac1ng  papillomavirus (HPV) tested women  Reversible Contracep1on: research to  evaluate a simple interven1on in primary  care.