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Pathology lab neoplasia 2

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Pathology lab   neoplasia 2 Pathology lab neoplasia 2 Presentation Transcript

  • General Pathology Neoplasia 2
  • Cytological features of malignancy Lesion : Remarkable variation in cell size and shape (Cellular polymorphism )and nuclear size and shape (nuclear polymorphism ) mitotic figures (M) and nuclear hyperchromatism.
    • Cytological features of malignancy
    • Necrosis (N) of the tumor related to ischaemia.
    • Organ: myometrium
    • Lesion: benign neoplasm of the uterine smooth muscle (L) surrounded by normal myometrium.
    • Diagnosis: Leiomyoma .
    • Organ: myometrium ( higher magnification)
    • Lesion: tumor margin well circumscribed and no evidence of local invasion and their is pseudocapsule (C).
    • organ: Breast
    • Lesion: the neoplasm has an irregular outline and the neoplastic cells invading the fatty tissue and collagenous stroma of the breast.
    • Diagnosis: malignant neoplasm of Breast.
    • organ: Breast ( higher magnification)
    • Lesion: hyperchromatic malignant cells can be seen infiltrating the surrounding adipose tissue.
    • Diagnosis: malignant neoplasm of Breast.
    • Lesion: the cells are commonly arranged in broad sheets and large nests (N) , formation of keratin* known as dyskeratosis (D), and forms lamellated pink-stained masses known as keratin pearls (KP).
    • Squamous cell Carcinoma.
    • Organ: Colon
    • Lesion: mitosis are seen and nuclear hyperchromatism and higher nuclear to cytoplasmic ratio .
    • Diagnosis: Adenocarcinoma ( well Differentiated )
    • Organ: Connective tissue
    • Lesion: Consist of various combination of spindle cells (S) ,cells resembling histiocytes (H) with pale foamy cytoplasm and malignant giant cells (G) mitotic figures are plentiful.
    • Diagnosis: Malignant Fibrous Histiocytoma.
  • Pathology: the Hidden Science that Saves Lives Pathology: is the Science behind the Cure
    • This pathology lab is prepared by, Dr. Omar Emad Ibrahim , Pathology Dep. Faculty of Medicine & Health Sciences, Thamar University .
    • The images is taken from
    Atlas of Basic Histopathology .