Intestinal permeability ppp i

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Intestinal permeability ppp i

  1. 1. Intestinal Permeability/leaky gut
  2. 2. Disruption of cells lining the intestine leads tointestinal hyperpermeability which has beenproposed by some researchers to involve arelationship with acute and chronic diseasessuch as systemic inflammatory responsesyndrome (SIRS), inflammatory boweldisease, diabetes, allergies, asthma, autism.
  3. 3. Can manifest in a variety of ways
  4. 4. Observations/ the evolution approach• Cavemen (pre-agriculturalists) and modern hunter gatherers did not suffer from the diseases of modern civilization.• The diets of hunter gather’s we free of grains, legumes and dairy.• Are genes are virtually identical to cavemen ( yeah but they are also virtually identical to chimps)• Grains , legumes and dairy are neolithic (new) foods.Invalid inference: We should eat devoid of grains, legumes and dairy. Just an observation. But a good one.
  5. 5. Yes more questions need to be asked
  6. 6. For example: we can find new food sources of food and adapt to it
  7. 7. Research/the anti-nutrient approach• Have we adapted to the consumption of grains• Are these evolutionary novel foods a problem with our biochemistry?• Well Plants have anti-nutrients as a defense mechanism. But it all depends on the digestive process.
  8. 8. Saponins are antinutrients
  9. 9. We need to consider this!
  10. 10. Other antinutrients
  11. 11. They are everywhere! Food is out to kill us! No not really. • Heat deactivates most of these antinutrients.• Also have to consider what happens when you consume these things as part of real foods.
  12. 12. Depends. If you don’t cook them well. yeah
  13. 13. ProlaminesStorage proteins. The above is gluten. Really tough to digest. We see this when we try to ferment it.

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