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• Lack of o2 availability in tissues 
Hypoxia 
• Relative deficiency of o2 in blood 
• Arterial Po2 <80 mmhg 
Hypoxemia 
• Lack of o2 utilization by tissues 
Dysoxia
Acceptable arterial o2 tensions at sea 
level(breathing 21% o2 )/room air 
Adult and child 
Normal 
Acceptable range 
Hypoxemia mild 
moderate 
Severe 
Pao2(mmHg) 
97 
>80 
60 
50 
40 
Sao2(%) 
97 
>95 
90 
80 
70
In new born 
40- 70 mm Hg (median value) of Pao2 is 
taken as normal
types 
1. 
• Hypoxic hypoxia/hypoxemic hypoxia 
2. 
• Anaemic hypoxia:- Anaemia &Dyshaemoglobinemia 
3. 
• Stagnant hypoxia 
4. 
• Histotoxic hypoxia
Low p 50 
As mentioned in Egan’s as the 5th type of 
hypoxia.
Consequences and implications 
Mild to moderate hypoxaemia is common in the postoperative period & is 
often underestimated 
The focus of this review is to provide an understanding of the reasons why 
post-operative oxygen therapy is necessary, with emphasis on the 
practicalities of delivering oxygen to the patient.
Mild to mod. hypoxemia 
Due to wide variability of 
patho physiology 
Post- op morbidity
Extreme hypoxemia 
Severe/permanent brain 
injury 
Cardiac arrest 
CPR
Surgical consequences 
Resistance to infection,wound 
healing,anastomotic integrity 
Loss of GI mucosal integrity 
Bacterial translocation and sepsis
Thank you

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olumide adeola pidan, olumide pidan

  • 1.
  • 2. • Lack of o2 availability in tissues Hypoxia • Relative deficiency of o2 in blood • Arterial Po2 <80 mmhg Hypoxemia • Lack of o2 utilization by tissues Dysoxia
  • 3. Acceptable arterial o2 tensions at sea level(breathing 21% o2 )/room air Adult and child Normal Acceptable range Hypoxemia mild moderate Severe Pao2(mmHg) 97 >80 60 50 40 Sao2(%) 97 >95 90 80 70
  • 4. In new born 40- 70 mm Hg (median value) of Pao2 is taken as normal
  • 5. types 1. • Hypoxic hypoxia/hypoxemic hypoxia 2. • Anaemic hypoxia:- Anaemia &Dyshaemoglobinemia 3. • Stagnant hypoxia 4. • Histotoxic hypoxia
  • 6. Low p 50 As mentioned in Egan’s as the 5th type of hypoxia.
  • 7. Consequences and implications Mild to moderate hypoxaemia is common in the postoperative period & is often underestimated The focus of this review is to provide an understanding of the reasons why post-operative oxygen therapy is necessary, with emphasis on the practicalities of delivering oxygen to the patient.
  • 8. Mild to mod. hypoxemia Due to wide variability of patho physiology Post- op morbidity
  • 9. Extreme hypoxemia Severe/permanent brain injury Cardiac arrest CPR
  • 10. Surgical consequences Resistance to infection,wound healing,anastomotic integrity Loss of GI mucosal integrity Bacterial translocation and sepsis