AlzforumWebinar
July 8th. 2014
 The variants with the highest functional
impact, do not need to show the most
significant association with disease risk
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Carlos Cruchaga Webinar July 2014

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Webinar presentation made by Dr. Carlos Cruchaga, July 8, 2014 - http://www.alzforum.org/webinars/mutations-impair-trem2-maturation-processing-and-microglial-phagocytosis

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Carlos Cruchaga Webinar July 2014

  1. 1. AlzforumWebinar July 8th. 2014
  2. 2.  The variants with the highest functional impact, do not need to show the most significant association with disease risk  CSF TREM2 levels  better biomarker than plasma levels  Is there any other variant (cis/trans) that affect CSF TREM2 levels?  Does the different TREM2 alternative transcript play a role in TREM2 function/pathogenesis?
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