Allergy

7,868 views
7,431 views

Published on

Allergic reaction includes the degranulation process, shown here

0 Comments
2 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total views
7,868
On SlideShare
0
From Embeds
0
Number of Embeds
32
Actions
Shares
0
Downloads
208
Comments
0
Likes
2
Embeds 0
No embeds

No notes for slide

Allergy

  1. 1. Allergy Degranulation Process
  2. 2. Allergy <ul><li>Activated mast cells go through a process called degranulation. They release histamine and other chemicals causing inflammation. </li></ul>
  3. 3. Allergy <ul><li>The antigen floats around the body … </li></ul>
  4. 4. Allergy <ul><li>IgE antibod ies find allergen and attach themselves to it. </li></ul>
  5. 5. Allergy <ul><li>IgE binds to IgE receptors on surface of mast cells (a type of immune cell) </li></ul><ul><li>This is a kind of FC receptor. </li></ul>
  6. 6. Allergy <ul><li>Stored mediators (4) such as histamine, proteases, chemokines and heparine are released from granules (5) </li></ul>
  7. 7. Allergy <ul><li>N ewly formed mediators also released (prostaglandins, leukotrienes, thromboxanes amd PAF) </li></ul>
  8. 8. Allergy <ul><li>Produced by Allergy-Details.com </li></ul><ul><li>Material from Wikipedia </li></ul><ul><li>Image by Paweł Kuźniar </li></ul>

×