Allergy
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Allergy

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Allergic reaction includes the degranulation process, shown here

Allergic reaction includes the degranulation process, shown here

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Allergy Presentation Transcript

  • 1. Allergy Degranulation Process
  • 2. Allergy
    • Activated mast cells go through a process called degranulation. They release histamine and other chemicals causing inflammation.
  • 3. Allergy
    • The antigen floats around the body …
  • 4. Allergy
    • IgE antibod ies find allergen and attach themselves to it.
  • 5. Allergy
    • IgE binds to IgE receptors on surface of mast cells (a type of immune cell)
    • This is a kind of FC receptor.
  • 6. Allergy
    • Stored mediators (4) such as histamine, proteases, chemokines and heparine are released from granules (5)
  • 7. Allergy
    • N ewly formed mediators also released (prostaglandins, leukotrienes, thromboxanes amd PAF)
  • 8. Allergy
    • Produced by Allergy-Details.com
    • Material from Wikipedia
    • Image by Paweł Kuźniar