With HIV the e pigallocatechingallate acts as a block to the HIV transport protein on the host cell
In cases of Dementia the epigallocatechingallate stops the formation of plaque and tangles by inducing the PKC pathway which increases the levels of α -secretase an enzyme the inhibits A β proteins a precursor to neurofibular tangles associated with Alzheimer's
Epigallocatechingallate has been shown to inhibit angiogenesis of tumor cell and thus not allowing them to become cancerous. This is achieved by stopping the production of angiogenic compounds in the tumor cells.
It has also been suggested that green tea may induce apoptosis in cancer cells by shutting down the NF-KB pathway.
Epigallocatechingallate prevents the breakdown of norepinephrine thus causing a raise in metabolism. It may also Inhibit adipocyte hypertrophy and hyperplasia, and possibly inhibit gastrointestinal enzymes involved in nutrient uptake, the mechanisms have yet to be deciphered for these processes.