Open about what you doOpen about what you knowOpen to new engagementSupporting others to be open
Semantic Web projects in life sciences and health care environments @Linkatu
Drug Development Process Early Clinical Discovery Development Dev. TI HI LO ECD PoC DfL Reg LCM Preclinical studies Clinical studies • Target Identification • Proof of Concept • Hit Identification • Development for Launch • Lead Optimisation • Registration and Launch • Life Cycle ManagementThe way to semantic ServiceOriented Architecture
$1,000 genome; $100,000 analysis?50 million sequencesobtained by 2015 The pharma industry loses $4.2 billion per year due to drug trial delays
http://www.flickr.com/photos/nic221/391536867/
1.5M publications/year1 15 million million authors readers at >10,000 institutions 1.5B downloads per year
20billion€
too much to read too expensivetoo difficult to find
http://linkedlifedata.com/
code.google.com/p/bio2rdf
what is a “data market place" ? Service that make it easy to find data from a range of secondary data sources, then consume the data in a usable and unified format. Several of these services are trying to create marketplaces for data, envisioning that data providers can offer their data sets for sale to data seekers
what is a "platform" ? a place where we encourage... support... enable... our communities
You own the dataYou control accessYou can pull it/change itYou can delete itYou can decide what is best
Translational Medicine Platform for Alzheimer´s DiseaseData Integration Platform for Patients, Physicians and ResearchersUse Tabs for play each role.http://85.48.202.13:8080/AD/index.html
Being a PatientMonitor your progressKnow Side Effects of Drugs you are takingMappings to Generic OntologiesICD9 Coded
Being a PhysicianMonitor your patientsRetrieve info from PubMedAnswer complex queriesAre there active clinical trials that my patients may participate with different MOAbecause of side effects?
Being a ResearcherRetrieve information from distributed sourcesGet the latest relevant scientific articlesAnswer complex queriesWhat Biomarkers are associated with or implicated in Alzheimer´s Disease?
Breast Cancer Decision Support Systemhttp://85.48.202.13:8080/BreastCancer/BC.htmlDeployed at Cruces Hospital – BilbaoUse of Description Logic and Inference Rules to deduce the Diagnosis and TreatmentCustomized Breast Cancer ontology
Information Retrieval from Distributed Sources for Breast CancerMatchmaking process between Patient´s PHR and Distributed SourcesRetrieves Information such as Clinical Trials, PubMed articles, Adjuvant Treatments, genes,…
Information Retrieval from Distributed Sources for Breast CancerMatchmaking process between Patient´s PHR and Distributed SourcesRetrieves Information such as Clinical Trials, PubMed articles, Adjuvant Treatments, genes,…
OmicsHubhttp://85.48.202.13:8080/SWDemo/index.jspThe inputs for the prototype will be a list of genes and a list of proteins which havebeen acquired from different time points of the lifecycle of a cell.Integrate Both DatasetsFind Relevant Pubmed ArticlesOrganize into clustersKnown Protein Interactions
Mendeley Snags $2 Million In Early-StageFunding For Research Paper Management Tool "Data marketplace" Infochimps raises $1.2M to build out its data offeringsFactual, a startup that claims to host hundredsof thousands of data sets, has raised $25million in its first round of institutional funding. Sermo Closes 26.7 Million in Funding to Evolve Online Community for Physicians PatientsLikeMe take in $8M funding
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