Introduction to Distributed Annotation System (DAS)

Introduction to the Distributed Annotation System Biohackathon 2 Alberto Labarga –alberto.labarga@scientifik.info

Distributed Annotation System • Developed in 1999/2000 by Lincoln Stein (CSHL) and collaborators as a GFF‐based web service. • Biodas.org (http://www.biodas.org): • A client‐server system in which a single client integrates information from multiple servers. • It allows a single machine to gather up genome annotation information from multiple distant websites, collate the information, and display it to the user in a single view.

General Feature Format Genome annotations, especially structural annotations, are often stored in • GFF (General Feature Format) files. GFF is a simple tab‐delimited data format. • Fields are: • <seqname> <source> <feature> <start> <end> <score> <strand> <frame> [attributes] [comments] See also: http://www.sanger.ac.uk/Software/formats/GFF/ •

DAS Concept Annotation server A Annotation server B Annotation server C Client Reference server

DAS Registry http://www.dasregistry.org

DAS Server • DAS request to retrieve the data sources • http://das.ensembl.org/das/dsn • Result:

DAS Server DAS request to retrieve features on a segment: • http://das.ensembl.org/das/ens_36_omim_genes/features?segment=1:1,1000000 • Result: •

Das viewer http://www.ebi.ac.uk/dasty

Introduction to Distributed Annotation System (DAS)

by Alberto Labarga on Mar 17, 2009

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