Your SlideShare is downloading. ×
Polymyalgia rheumatica
Polymyalgia rheumatica
Polymyalgia rheumatica
Polymyalgia rheumatica
Polymyalgia rheumatica
Polymyalgia rheumatica
Polymyalgia rheumatica
Polymyalgia rheumatica
Polymyalgia rheumatica
Polymyalgia rheumatica
Upcoming SlideShare
Loading in...5
×

Thanks for flagging this SlideShare!

Oops! An error has occurred.

×
Saving this for later? Get the SlideShare app to save on your phone or tablet. Read anywhere, anytime – even offline.
Text the download link to your phone
Standard text messaging rates apply

Polymyalgia rheumatica

369

Published on

Published in: Education, Health & Medicine
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total Views
369
On Slideshare
0
From Embeds
0
Number of Embeds
0
Actions
Shares
0
Downloads
11
Comments
0
Likes
0
Embeds 0
No embeds

Report content
Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel
No notes for slide

Transcript

  • 1. POLYMYALGIA RHEUMATICA Dr. Arshad Rabbani MBBS,MCPS,FCPS
  • 2. is a clinical syndrome characterized by severe aching and stiffness in the neck, shoulder girdle, and pelvic girdle.
  • 3. Pathophysiology    causes severe pain in the proximal muscle groups; however, no evidence of disease is present at muscle biopsy. Muscle strength and electromyographic findings are normal.  cell-mediated injury to the elastic lamina in the blood vessels in the affected muscle groups.
  • 4. Incidence     Frequency 1 in 200 people aged 50 years or older. Mortality/Morbidity not a life-threatening disease, but it does require treatment for 2-4 years. Race whites >other ethnic groups Sex Females are affected twice as often as males.
  • 5. Symptoms         Pain and stiffness in the proximal muscle groups that usually is symmetrical and worse in the morning. Gel phenomenon (stiffness after prolonged inactivity). Fever (low grade). Weight loss. Fatigue. Depression. No weakness. Abrupt onset of symptoms.
  • 6. Signs    No muscle atrophy. Muscle tenderness. Decreased active range of motion of joints secondary to pain.
  • 7. Lab studies     Erythrocyte sedimentation rate greater than 50 mm/h Normochromic normocytic anemia in 50% of cases Normal creatinine kinase level Negative finding for rheumatoid factor    Mild elevations with liver function test results Mild nonspecific synovitis Negative muscle biopsy findings
  • 8. Treatment  Corticosteroids e.g. prednisone 5-60 mg/d PO qd or divided bid/qid; taper over 2 wk as symptoms resolve.
  • 9. Prognosis    The average length of disease is 3 years. Exacerbations may occur if steroids are tapered too rapidly. Relapse is common.

×