Dr. Arshad Rabbani
is a clinical syndrome characterized by severe
aching and stiffness in the neck, shoulder
girdle, and pelvic girdle.
causes severe pain in the proximal muscle
groups; however, no evidence of disease is
present at muscle biopsy.
Muscle strength and electromyographic
findings are normal.
cell-mediated injury to the elastic lamina in the
blood vessels in the affected muscle groups.
1 in 200 people aged 50 years or older.
not a life-threatening disease, but it does
require treatment for 2-4 years.
whites >other ethnic groups
Females are affected twice as often as males.
Pain and stiffness in the proximal muscle groups
that usually is symmetrical and worse in the
Gel phenomenon (stiffness after prolonged
Fever (low grade).
Abrupt onset of symptoms.
No muscle atrophy.
Decreased active range of motion of joints
secondary to pain.
rate greater than 50 mm/h
anemia in 50% of cases
Normal creatinine kinase
Negative finding for
Mild elevations with liver
function test results
Mild nonspecific synovitis
Negative muscle biopsy
Corticosteroids e.g. prednisone
5-60 mg/d PO qd or divided bid/qid; taper
over 2 wk as symptoms resolve.
The average length of disease is 3 years.
Exacerbations may occur if steroids are
tapered too rapidly.
Relapse is common.
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