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  • 1. Anatomical Parts of Stomach
  • 2. Fundus of Stomach Gastric Rugae (GR) Longitudinal branching Folds in empty stomach. GR 4 Layers: 1) Mucosa (M) 2) Submucosa (SM) 3) Musculosa ; *Inner oblique (IO) *Middle Circular (MC) *Outer Longitudinal (OL) 4) Serosa M SM IO MC OL
  • 3. Wall of Fundus of the Stomach Mucosa, Submucosa, Musculosa & Serosa
  • 4. Parts & Cells of Fundic Glands
  • 5. Fundic Glands: * Occupy most of mucosal thickness. * Perpendicular to the surface, reaching to muscularis mucosa (MM). MM *Very Crowded Minimal C.T. .
  • 6. * Simple Branched Tubular Glands. * Open into lumen by short narrow ducts (Gastric Pits) * Pit: Secretory Portion : 1:3
  • 7. MM MM: Muscularis Mucosa
  • 8. Surface Mucous Cells: * Simple Columnar cells with basal oval Nuclei. * Line the surface epithelium and extend to line the pits . Function: Secrete “Neutral Mucus” which forms a “thick Blanket” for lubrication & protection.
  • 9. Fundic Stomach with a short pit Surface mucus secreting epithelium
  • 10. Mucous Neck Cells * Located at the neck of the glands. * Low Columnar Cells with Vacuolated foamy cytoplasm. * Function: Secrete “Acidic Mucus” which protect gastric mucosa.
  • 11.
    • Found mainly in the upper parts of the gland
    • Large , rounded or triangular with central rounded nucleus.
    • DO NOT reach lumen.
    • Deeply acidophilic cytoplasm.
    OXYNTIC (PARIETAL) Cells: (Arrows)
    • Functions:
    • Secretion of:
    • HCL.
    • 2) Intrinsic
    • Anti-pernicious anemia Factor
  • 12. Peptic (Chief) Cells: The most numerous type. Found mainly at the BASE of glands . Pyramidal cells with basal rounded nuclei. Basal basophilic cytoplasm & apical zymogen granules .
    • Functions:
    • Secretion of:
    • Pepsinogen-------Pepsin
    • 2) Re nn in.
    • 3) Little amount of lipase .
  • 13.  
  • 14.  
  • 15. Fundic Gastric Glands Parietal Cells
  • 16. Musculosa of Fundus: 3 Layers Inner oblique (IO), Middle Circular (MC) and Outer Longitudinal (OL).
  • 17. GP: Gastric Pits, MM: Muscularis Mucosa. M: Mucosa S: Submucosa. O: Inner Oblique C: Middle Circular L: Outer Longitudinal.
  • 18. Pyloric Stomach MM – muscularis mucosa G Pits (P) are Deep, long and Wide. Pyloric Glands:
    • Not Crowded, short occupy ½ thickness of mucosa .
    • Highly coiled, branched tubular.
    • Lined mainly with mucous cells .
  • 19. Ratio between Pit (P): secretory Portion (G) : 1:1 P G
  • 20.  
  • 21. Musculosa Of Pylorus 2 Layers Inner Circular (IC) Outer Longitudinal (OL) Circular muscle is Thickened to form “ Pyloric Sphincter ” (PS ) IC OL (PS)
  • 22. Pyloroduodenal Junction duodenum pylorus Pyloric sphincter Brunner’s glands
  • 23. Pyloro-Duodenal Junction
  • 24. Identify the organ (be specific). Describe the characters of the glands. (2)
  • 25. This is a section in the fundic glands Identify the cell indicated by the arrow. (3)
  • 26. (4) a) Identify the cell indicated by the black arrow. b) Identify the layer indicated by the red arrow. This is a section in the lower part of the fundic glands:
  • 27. (a) (b) (5) (a) & (b) are sections in the fundus of the stomach. Identify the layer indicated by the arrow in (a) & (b).
  • 28. (a) (b) (6) i) In slides a & b , identify the organs. ii) Identify 1, 2 & 3 in each slide.
  • 29. (8)
    • Identify the organ (be specific).
    • b) What does the black arrow point to?
    • c) Mention the type of glands pointed to by the red arrow?
  • 30. 13- Identify the organ. 14- Identify the structure indicated by the arrow. 15- Identify the tissue indicated by the arrow. 16- identify the structure indicated by the arrow. 16 (9)
  • 31. (10) a) Identify the type of junction. b) Name the abbreviations marked by the letters: S – D – PS – G- CM - LM
  • 32.
    • This is a section in the Fundus of Stomach
    • Identify the layer indicated by the arrow .
    • Identify ME.