Amyloid plaques

1,034
-1

Published on

Quick Reminder of Amyloid formation and anti-amyloid drugs.

0 Comments
3 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total Views
1,034
On Slideshare
0
From Embeds
0
Number of Embeds
1
Actions
Shares
0
Downloads
10
Comments
0
Likes
3
Embeds 0
No embeds

No notes for slide

Amyloid plaques

  1. 1. Amyloid Plaques
  2. 2. PHYSIOLOGICAL PATHWAY: Alpha Secretase
  3. 3. PATHOLOGICAL PATHWAY: Beta Secretase
  4. 4. Beta Secretase Inhibitors• Merck: MK-8931• Lilly: LY450139Severe adverseEffects: cancer
  5. 5. Gamma Secretase Inhibitors• Merck: MK-8931• Eisai: E 2609• Lilly: LY2886721 In clinical trials
  6. 6. Monoclonal Antibodies against Abeta 42 *Solanezumab (Lilly) *Bepaneuzumaub (Pfizer) - failed
  1. A particular slide catching your eye?

    Clipping is a handy way to collect important slides you want to go back to later.

×