Chronic candidiasis


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Chronic candidiasis

  1. 1. Chronic candidiasis<br />Done by : AbdulrahmanSulaiman Al-Otaiq<br />
  2. 2. Chronic candidiasis<br /> 1. CHRONIC ATROPHIC CANDIDIASIS<br />Denture stomatitis (denture sore mouth)<br />Angular cheilitis<br />Median rhomboid glossitis<br />2. CHRONIC MULTIFOCAL CANDIDIASIS<br />3. Chronic hyperplastic C (candidaleukoplakia)<br />4- chronic mucocutaneouscandidiasis(secondry to systemic disease specially endocrine diseases)<br />
  3. 3. Predisposing factor of chronic candidiasis:<br />poor oral hygiene<br />Xerostomia<br /> Compromised Immune system.<br />Recent antibiotic treatment<br />Dental appliance<br />Early infancy<br />AIDS<br />Corticosteroid<br />Pregnancy <br />Anemia<br />Diabetes mellitus<br />
  4. 4. Denture sore mouth<br />Denture stomatitisis a common form of oral candidiasis<br />Manifests as a diffuse inflammation of the maxillary denture-bearing areas .<br />Often associated with angular cheilitis.<br />
  5. 5. At least 70% of individuals with clinical signs of denture stomatitis exhibit fungal growth, <br />and this condition most likely results from yeast colonization of the oral mucosa, combined with bacterial colonization.<br />
  6. 6. Chronic Atrophic Candidiasis (Denture Sore Mouth)<br />Appearance:<br /><ul><li>Mucosa beneath denture is erythematous with a well-demarcated border.
  7. 7. Swabs from the mucosal surface may provide a prolific growth, but biopsy shows few candidahyphae in spite of high serum and saliva antibodies to candida.</li></ul>Differential Diagnosis:<br /><ul><li>Inflammatory papillary hyperplasia.</li></li></ul><li>Denture stomatitis<br />
  8. 8. Three progressive clinical stages of denture sore :<br />1. numerous palatal petechiae .<br />2. displays amore diffuse erythema involving most (if not all) of the denture-covered mucosa. <br />3. includes the development of tissue granulation or nodularity(papillary hyperplasia) commonly involving the central areas of the hard palate and alveolar ridges.<br />
  9. 9.
  10. 10. Denture sore mouth is rarely found under a mandibular denture. <br />One possible explanation for this is that the negative pressure that forms under the maxillary denture excludes salivary<br /> antibody from this region, and yeast may reproduce,undisturbed, in the space between the denture and mucosa.<br />
  11. 11. Angular Cheilitis<br />is the term used for aninfectioninvolving the lip commissures. <br />There is frequently a coexistent denture stomatitis, and angular cheilitis is uncommonin patients with a natural dentition.<br />
  12. 12. Etiologic of Angular Cheilitis<br />reduced vertical dimension wiche may case nutritional deficiency (iron deficiency anemia and vitamin B or folic acid deficiency) sometimes referred to as perlèche<br />(more rarely) diabetes, neutropenia, and AIDS, <br />Staphylococcus and beta hemolytic Streptococcus. <br />
  13. 13. Angular cheilitis<br />
  14. 14. Erythematous patches of atrophic papillae located in the central area of the dorsum of the tongue <br />Considered a form of chronic atrophic candidiasis<br />These lesions were originally thought to be developmental in nature but are now considered to be a manifestation of chronic candidiasis.<br />Median Rhomboid glossitis<br />
  15. 15. Median Rhomboid glossitis<br />
  16. 16. CHRONIC MULTIFOCAL CANDIDIASIS<br /><ul><li> Patients may present with multiple areas of chronic atrophiccandidiasis.
  17. 17. These are most often seen in immunocompromised</li></ul>individuals or in patients with predisposing factors suchas ill-fitting dentures. <br />
  18. 18. The changes frequently affect<br />The dor-sum of the tongue . <br />midline of the hard palate (kissingLesions).<br />commissurearea (angular cheilitis) .<br />Denture bearing mucosal surfaces. <br /><ul><li>Smoking may also play an important role in immunocompetent patients</li></li></ul><li>THANK YOU <br /> Reference :<br />Burket's Oral Medicine, chapter 5<br />