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This hypertextual presentation derives from a nearly completed hypertext book on the co-evolution of and revolutions in tools humans use and human cognition (see below), and was tailored for an atheists and freethinkers group interested in what paleontology, archeology and human genomics have to say about the human origins of religion. Comprehensively detailed scientific evidence for the evolution of modern humans from our primate ancestry leaves no gaps in our long evolution that need any kind of mystical explanation to account for our existence. The presentation begins with a consideration of the biophysical nature of life and the philosopher Karl Popper’s construction of an evolutionary theory of knowledge. These foundation stones explain how natural selection works. The recent development of genomic technology, has enabled detailed genomes to be constructed for many humans, all of the great apes, and two extinct human species, the Neanderthals and Denisovans. The genomes plot the detailed sequences for some 3 billion DNA nucleotides for each species. Humans are 99% identical and chimpanzees / bonobos down to the nucleotide level, 98.4% identical to gorillas, and 97.4% identical to orangutans. Given the vast number of data-points it is easy to unambiguously reconstruct details of the relationships and relative times of speciation in the ancestry. Although scrappy fossils are notoriously difficult to reconstruct they do establish the presence of certain lineages in particular geographic areas. Various forms of radioactive decay allow their ages to be determined with some considerable accuracy. It is clear that we share a “last” common ancestor with chimpanzees and bonobos some 5-7 million years ago. Paleoarcheological evidence traces the initially gradual development of tool use over that period of time. Several videos in the presentation demonstrate that the great apes are also surprisingly accomplished tool users. This evidence is then used to construct in detail the evolution of small-brained tool-using ape men into spear and fire equipped top carnivores into today’s big-brained modern men that are dominating the entire planet. Human speech probably emerged only in the last 100,000 – 200,000 years ago. With the emergence of speech, people could begin to speculate about their origins – positing earth mothers and angry sky gods. Only in the last few decades has the evidence become strong enough to show there is no need for mystical gods and creators to explain human origins. When the writing and editorial work on the book “Application Holy Wars or a New Reformation – A Fugue on the Theory of Knowledge” is finished, it will be published via Kororoit Institute (http://kororoit.org). Crowd funding will be sought to complete the editorial and publishing work. The argument of that book is structured as a fugue, crossing many disciplinary paradigms.