VisualSonics VevoStrain Technology Provides Earlier Access To Left Ventricular Dysfunctions

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VisualSonics Inc., a leader in real time, in vivo, high-resolution micro-imaging systems and a wholly-owned subsidiary of SonoSite Inc., announced today that its VevoStrain™ technology has been featured on the cover of the April 15, 2011 issue of Circulation Research, Journal of the American Heart Association.

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VisualSonics VevoStrain Technology Provides Earlier Access To Left Ventricular Dysfunctions

  1. 1. VisualSonics VevoStrain Technology Provides EarlierAccess To Left Ventricular DysfunctionsPosted April 14th, 2011 in In the NewsA new dimension of diagnostic information:Strain analysis feature of Vevo® 2100 high-frequency ultrasound system enables highly sensitiveand rapid measurement of global (whole heart) and regional (specific heart areas) cardiacfunction.TORONTO, Canada – April 14, 2011 – VisualSonicsInc., a leader in real time, in vivo, high-resolution micro-imaging systems and a wholly-owned subsidiary ofSonoSite Inc., announced today that its VevoStrain™technology has been featured on the cover of the April 15,2011 issue of Circulation Research, Journal of theAmerican Heart Association.VevoStrain provides advanced imaging and quantificationcapabilities to study sensitive movements in the heartmuscles – specifically the myocardium. The VevoStrain technology augments high-resolutionimaging capabilities of high-frequency ultrasound with highly sensitive measurements of subtlevariations in the myocardium. The VevoStrain software enables tracking of wall motions in theheart, including the entire heart as well as defined regions within the heart. Measurementcapabilities include quantification of displacement, velocity, strain and strain rate. Researchers1at Brigham and Women’s Hospital, Harvard Medical School present the utility of VevoStraintechnology as a non invasive, highly sensitive and rapid cardiac phenotyping tool in theirseminal paper on in vivo strain analysis.Ronglih Liao, MD, Associate Professor of Medicine, Harvard Medical School said, “We believethat with strain analysis, we now have a very effective and efficient method for non-invasivelydetecting early cardiac performance irregularities in mice. While recognizing that this methodrequires special expertise and experience to implement, we are very excited about prospects forapplying these analyses in future studies of experimental therapeutics.”The VevoStrain software is emerging as the new state-of-the-art assessment tool for quantifyingmyocardial mechanical function and deformation, replacing Tissue Doppler imaging, which hasbeen used in the past. Additional features of the software include measurement of cardiac wallmotion abnormalities, dyssynchrony (delayed ventricular activation and contraction) andmyocardial mechanics.More information on VevoStrain software is available at:http://www.visualsonics.com/vevostrain
  2. 2. About VisualSonicsVisualSonics is the world leader in real time, in vivo, high-resolution micro imaging systemsdesigned specifically for preclinical research and a wholly-owned subsidiary of SonoSite, Inc.(Nasdaq:Sono). The Company’s cutting edge technologies allow researchers at the world’s mostprestigious pharmaceutical and biotechnology companies, hospitals and universities to conductresearch in cardiovascular, cancer, neurobiology and developmental biology areas. The microimaging technologies support research applications that include genetic research, phenotypicstudies and drug development. VisualSonics micro imaging platforms combine high-resolution,real time in vivo imaging at reasonable cost with ease-of-use and quantifiable results.About SonoSiteSonoSite, Inc. (www.sonosite.com) is the innovator and world leader in bedside and point-of-care ultrasound and an industry leader in ultra high-frequency micro-ultrasound technology andimpedance cardiography equipment. Headquartered near Seattle, the company is represented byfourteen subsidiaries and a global distribution network in over 100 countries. SonoSite’s small,lightweight systems are expanding the use of ultrasound across the clinical spectrum by cost-effectively bringing high-performance ultrasound to the point of patient care.1 Bauer M, Cheng S, Liao R; Echocardiographic Speckle-Tracking Based Strain Imaging for Rapid CardiovascularPhenotyping in Mice; CIRCRESAHA/2010/239574-R1

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