Allergic Rhinitis Drugs Market Forecast 2014-2024
 

Allergic Rhinitis Drugs Market Forecast 2014-2024

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For an Executive Summary of this report please contact ediz.ibrahim@visiongain.com (+44 (0)20 7549 9976) or refer to our website ...

For an Executive Summary of this report please contact ediz.ibrahim@visiongain.com (+44 (0)20 7549 9976) or refer to our website https://www.visiongain.com/Report/1306/Allergic-Rhinitis-Drugs-Market-Forecast-2014-2024

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Allergic Rhinitis Drugs Market Forecast 2014-2024 Allergic Rhinitis Drugs Market Forecast 2014-2024 Document Transcript

  • Allergic Rhinitis Drugs Market Forecast 2014-2024 Future Prospects for Companies in Antihistamines, Corticosteroids, Immunotherapy & Vaccines ©notice This material is copyright by visiongain. It is against the law to reproduce any of this material without the prior written agreement of visiongain. You cannot photocopy, fax, download to database or duplicate in any other way any of the material contained in this report. Each purchase and single copy is for personal use only.
  • Contents 1. Report Overview 1. Report Overview 1.1 Global Allergic Rhinitis Drugs Market Overview 1.2 Global Allergic Rhinitis Drugs Market Segmentation 1.3 Why You Should Read This Report 1.4 How This Report Delivers 1.5 Key Questions Answered by This Analytical Report 1.6 Who is This Report For? 1.7 Methodology 1.8 Frequently Asked Questions (FAQ) 1.9 Associated Visiongain Reports 1.10 About Visiongain 2. Introduction to Allergic Rhinitis 2. Introduction to Allergic Rhinitis 2.1 The Pharmaceutical Industry: a Very Brief Overview 2.2 A Brief Overview of Allergy 2.3 Allergic Rhinitis 2.3.1 The Global Prevalence of Allergic Rhinitis 2.3.2 Pathophysiology of Allergic Rhinitis: IgEs and Mast Cells 2.3.3 Symptoms of Allergic Rhinitis 2.3.4 Classification of Allergic Rhinitis 2.3.4.1 Non-Allergic Rhinitis and Mixed Rhinitis 2.3.5 Seasonal Allergic Rhinitis (Hay Fever) 2.3.6 Perennial Allergic Rhinitis www.visiongain.com
  • Contents 2.3.7 Diagnosis of Allergic Rhinitis 2.4 Treatment of Allergic Rhinitis 2.4.1 Antihistamines 2.4.1.1 First-Generation Antihistamines 2.4.1.2 Second- and Third-Generation Antihistamines 2.4.2 Corticosteroids 2.4.2.1 First-, Second- and Third-Generation Intranasal Corticosteroids 2.4.2.2 Combination Drug Products 2.4.3 Leukotriene Receptor Antagonists 2.4.4 Cromolyn (cromoglicic acid) 2.4.5 Decongestants 2.4.6 Saline Nasal Sprays 2.4.7 Immunotherapy and Vaccines 2.5 Phases of Clinical Trials 2.6 Scope of this Report 2.7 Currency Exchange Rates in This Report 3. Allergic Rhinitis Drugs: World Market 2014-2024 3. Allergic Rhinitis Drugs: World Market 2014-2024 3.1 The World Allergic Rhinitis Drugs Market in 2013 3.1.1 Leading Allergic Rhinitis Drugs 3.1.2 Leading Companies in the Allergic Rhinitis Drugs Market 3.2 World Allergic Rhinitis Drugs Market: Sales Forecast 2014-2024 3.3 Oral Antihistamines Lead the World Allergic Rhinitis Drugs Market 3.4 How Will Segmental Market Shares Change to 2024? www.visiongain.com
  • Contents 3.5 World Allergic Rhinitis Drugs Market: Drivers and Restraints 2014-2024 4. Leading National Markets 2014-2024 4. Leading National Allergic Rhinitis Drugs Markets 2014-2024 4.1 Geographical Breakdown of the World Allergic Rhinitis Drugs Market 4.2 World Allergic Rhinitis Drugs Market: National Markets Forecast 2014-2024 4.2.1 How Will National Market Shares Change to 2024? 4.3 The US Allergic Rhinitis Drugs Market 2014-2024 4.3.1 US Allergic Rhinitis Drugs Market Forecast 2014-2024 4.3.2 US Allergic Rhinitis Drugs Market: Trends and Developments 4.3.2.1 Rx-to-OTC Switching of Intranasal Corticosteroids 4.3.2.2 Affordable Care Act: Expanding Medicare Coverage 4.4 Chinese Allergic Rhinitis Drugs Market 2014-2024 4.4.1 Chinese Allergic Rhinitis Drugs Market Forecast 2014-2024 4.4.2 Chinese Allergic Rhinitis Drugs Market: Trends and Developments 4.4.2.1 Air Pollution Associated With Increasing Prevalence 4.4.2.2 Expansion of Healthcare Coverage and Reimbursement 4.5 Japanese Allergic Rhinitis Drugs Market 2014-2024 4.5.1 Japanese Allergic Rhinitis Drugs Market Forecast 2014-2024 4.5.2 Japanese Allergic Rhinitis Drugs Market: Trends and Developments 4.5.2.1 Cedar Reforestation and the Hay Fever Epidemic 4.5.2.2 Generic Penetration to Reach 60% by 2018? 4.5.2.3 Genetically Modified Rice as Immunotherapy 4.6 EU5 Allergic Rhinitis Drugs Market 2014-2024 4.6.1 German Allergic Rhinitis Drugs Market Forecast 2014-2024 www.visiongain.com
  • Contents 4.6.2 French Allergic Rhinitis Drugs Market Forecast 2014-2024 4.6.3 UK Allergic Rhinitis Drugs Market Forecast 2014-2024 4.6.4 Italian Allergic Rhinitis Drugs Market Forecast 2014-2024 4.6.5 Spanish Allergic Rhinitis Drugs Market Forecast 2014-2024 4.6.6 EU5 Allergic Rhinitis Drugs Market: Trends and Developments 4.6.6.1 Germany: Reform of AMNOG Pharmaceutical Rebate Law 4.6.6.2 France: Social Security Finance Bill 2014 4.6.6.3 UK: Increasing Burden of Allergy 4.6.6.4 Italy: Austerity Measures Limiting Growth 4.6.6.5 Spain: The Start of Recovery in the Spanish Economy 4.7 Russian Allergic Rhinitis Drugs Market 2014-2024 4.7.1 Russian Allergic Rhinitis Drugs Market Forecast 2014-2024 4.7.2 Russian Allergic Rhinitis Drugs Market: Trends and Developments 4.7.2.1 Pharma2020 and the Russian Pharmaceutical Industry 4.8 Indian Allergic Rhinitis Drugs Market 2014-2024 4.8.1 Indian Allergic Rhinitis Drugs Market Forecast 2014-2024 4.8.2 Indian Allergic Rhinitis Drugs Market: Trends and Developments 4.8.2.1 Drug Prices Control Order 2013 4.8.2.2 Expansion of Healthcare Provision 4.9 Brazilian Allergic Rhinitis Drugs Market 2014-2024 4.9.1 Brazilian Allergic Rhinitis Drugs Market Forecast 2014-2024 4.9.2 Brazilian Allergic Rhinitis Drugs Market: Trends and Developments 4.9.2.1 Increasing Access to Medicines 4.10 Mexican Allergic Rhinitis Drugs Market 2014-2024 www.visiongain.com
  • Contents 4.10.1 Mexican Allergic Rhinitis Drugs Market Forecast 2014-2024 4.10.2 Mexican Allergic Rhinitis Drugs Market: Trends and Developments 4.10.2.1 Seguro Popular: Mexican Healthcare Reform 5. Oral Antihistamines Market 2014-2024 5. Oral Antihistamines Market 2014-2024 5.1 Oral Antihistamines: A Market in Decline 5.2 Leading Oral Antihistamines in 2013 5.3 Oral Antihistamines: Market Forecast 2014-2024 5.4 Market Share of Leading Oral Antihistamines to 2024 5.5 Oral Antihistamines: Trends and Developments 5.5.1 Patent Expiry and Generic Competition 5.5.2 The Rx-to-OTC Rush 5.5.3 Combination Therapy with Intranasal Corticosteroids 5.6 Allegra/Allegra-D/Allegra OTC (fexofenadine, Sanofi) 5.6.1 Allegra/Allegra OTC: Sales Forecast 2014-2024 5.7 Zyrtec/Zyrtec D (cetirizine, Johnson & Johnson/UCB/GSK) 5.7.1 Zyrtec/Zyrtec D: Sales Forecast 2014-2024 5.8 Claritin/Claritin OTC (loratadine, Merck & Co.) 5.8.1 Claritin/Claritin OTC: Sales Forecast 2014-2024 5.9 Xyzal (levocetirizine, Sanofi/UCB/GSK) 5.9.1 Xyzal: Sales Forecast 2014-2024 5.10 Allelock (olopatadine, Kyowa Hakko Kirin) 5.10.1 Allelock: Sales Forecast 2014-2024 5.11 Clarinex (desloratadine, Merck & Co.) www.visiongain.com
  • Contents 5.11.1 Clarinex: Sales Forecast 2014-2024 5.12 Talion (bepotastine, Mitsubishi Tanabe) 5.12.1 Talion: Sales Forecast 2014-2024 5.13 Ebastel (ebastine, Almirall/Takeda/Dainippon Sumitomo) 5.13.1 Ebastel: Sales Forecast 2014-2024 5.14 Other Oral Antihistamines 6. Intranasal Corticosteroids Market 2014-2024 6. Intranasal Corticosteroids Market 2014-2024 6.1 Intranasal Corticosteroids: First-line for Allergic Rhinitis 6.2 Leading Intranasal Corticosteroids in 2013 6.3 Intranasal Corticosteroids: Market Forecast by Value, 2014-2024 6.4 Intranasal Corticosteroids: Market Forecast by Volume, 2014-2024 6.5 Market Share of Leading Intranasal Corticosteroids to 2024 6.6 Intranasal Corticosteroids: Trends and Developments 6.6.1 Nasonex Patent Expiry in 2014 6.6.2 Nasacort AQ Switched to OTC 6.7 Nasonex (mometasone, Merck) 6.7.1 Nasonex: Sales Forecast by Value, 2014-2024) 6.7.2 Nasonex: Sales Forecast by Volume, 2014-2024) 6.8 Avamys/Veramyst (fluticasone furoate, GSK) 6.8.1 Avamys/Veramyst: Sales Forecast by Value, 2014-2024) 6.8.2 Avamys/Veramyst: Sales Forecast by Volume, 2014-2024) 6.9 Flixonase/Flonase (fluticasone propionate, GSK) 6.9.1 Flixonase/Flonase: Sales Forecast by Value, 2014-2024) www.visiongain.com
  • Contents 6.9.2 Flixonase/Flonase: Sales Forecast by Volume, 2014-2024) 6.10 Rhinocort (budesonide, AstraZeneca) 6.10.1 Rhinocort: Sales Forecast by Value, 2014-2024) 6.10.2 Rhinocort: Sales Forecast by Volume, 2014-2024) 6.11 Omnaris (ciclesonide, Dainippon Sumitomo/Takeda) 6.11.1 Omnaris: Sales Forecast by Value, 2014-2024) 6.11.2 Omnaris: Sales Forecast by Volume, 2014-2024) 6.12 Beconase/Beconase AQ (beclometasone, GSK/Omega Pharma) 6.12.1 Beconase/Beconase AQ: Sales Forecast by Value, 2014-2024) 6.12.2 Beconase/Beconase AQ: Sales Forecast by Volume, 2014-2024) 6.13 Nasacort (triamcinolone, Sanofi) 6.13.1 Nasacort: Sales Forecast by Value, 2014-2024) 6.13.2 Nasacort: Sales Forecast by Volume, 2014-2024) 6.14 QNasl (beclometasone, Teva) 6.14.1 QNasl: Sales Forecast by Value, 2014-2024) 6.14.2 QNasl: Sales Forecast by Volume, 2014-2024) 6.15 Zetonna (ciclesonide, Dainippon Sumitomo) 6.15.1 Zetonna: Sales Forecast by Value, 2014-2024) 6.15.2 Zetonna: Sales Forecast by Volume, 2014-2024) 6.16 Generic Intranasal Corticosteroids 6.16.1 Generic Intranasal Beclometasone 6.16.1.1 Generic Intranasal Beclometasone: Sales Forecast by Value, 2014-2024 6.16.1.2 Generic Intranasal Beclometasone: Sales Forecast by Volume, 2014-2024 6.16.2 Generic Intranasal Budesonide www.visiongain.com
  • Contents 6.16.2.1 Generic Intranasal Budesonide: Sales Forecast by Value, 2014-2024 6.16.2.2 Generic Intranasal Budesonide: Sales Forecast by Volume, 2014-2024 6.16.3 Generic Intranasal Flunisolide 6.16.3.1 Generic Intranasal Flunisolide: Sales Forecast by Value, 2014-2024 6.16.3.2 Generic Intranasal Flunisolide: Sales Forecast by Volume, 2014-2024 6.16.4 Generic Intranasal Fluticasone 6.16.4.1 Generic Intranasal Fluticasone: Sales Forecast by Value, 2014-2024 6.16.4.2 Generic Intranasal Fluticasone: Sales Forecast by Volume, 2014-2024 6.16.5 Generic Intranasal Mometasone 6.16.5.1 Generic Intranasal Mometasone: Sales Forecast by Value, 2014-2024 6.16.5.2 Generic Intranasal Mometasone: Sales Forecast by Volume, 2014-2024 6.16.6 Generic Intranasal Triamcinolone 6.16.6.1 Generic Intranasal Triamcinolone: Sales Forecast by Value, 2014-2024 6.16.6.2 Generic Intranasal Triamcinolone: Sales Forecast by Volume, 2014-2024 7. Intranasal Antihistamines Market 2014-2024 7. Intranasal Antihistamines Market 2014-2024 7.1 Intranasal Antihistamines: A Niche Segment 7.2 Leading Intranasal Antihistamines in 2013 7.3 Intranasal Antihistamines: Market Forecast by Value, 2014-2024 7.4 Intranasal Antihistamines: Market Forecast by Volume, 2014-2024 7.5 Market Share of Leading Intranasal Antihistamines to 2024 7.6 Intranasal Antihistamines: Trends and Developments 7.6.1 Azelastine versus Olopatadine 7.6.2 Intranasal Combination Products www.visiongain.com
  • Contents 7.7 Astepro (azelastine, Meda) 7.7.1 Astepro: Sales Forecast 2014-2024 7.8 Patanase (olopatadine, Novartis) 7.8.1 Patanase: Sales Forecast 2014-2024 7.9 Astelin (azelastine, Meda) 7.9.1 Astelin: Sales Forecast 2014-2024 7.10 Dymista (azelastine/fluticasone, Meda) 7.10.1 Dymista: Sales Forecast 2014-2024 7.11 Generic Intranasal Azelastine 7.11.1 Generic Intranasal Azelastine: Sales Forecast by Value, 2014-2024 7.11.1 Generic Intranasal Azelastine: Sales Forecast by Volume, 2014-2024 7.12 Generic Intranasal Olopatadine 7.12.1 Generic Intranasal Azelastine: Sales Forecast by Value, 2014-2024 7.12.2 Generic Intranasal Azelastine: Sales Forecast by Volume, 2014-2024 8. Immunotherapy and Vaccines Market 2014-2024 8. Immunotherapy and Vaccines Market 2014-2024 8.1 Immunotherapy: Set for Rapid Expansion 8.2 Leading Immunotherapy Products in 2013 8.3 Immunotherapy: Market Forecast 2014-2024 8.4 Market Share of Leading Immunotherapy Products to 2024 8.5 Immunotherapy: Leading Companies 8.6 Immunotherapy: Trends and Developments 8.6.1 Subcutaneous and Sublingual Immunotherapy 8.6.2 Expansion into the US Market www.visiongain.com
  • Contents 8.6.3 Standardisation of Immunotherapy Products 8.6.4 Immunotherapy as a Preventative Treatment 8.7 Staloral (Grass pollen allergen extract, Stallergenes) 8.7.1 Staloral: Sales Forecast 2014-2024 8.8 Alutard SQ (Grass pollen allergen extract, ALK-Abelló) 8.8.1 Alutard SQ: Sales Forecast 2014-2024 8.9 Grazax/Grastek (Timothy grass pollen allergen extract, ALK-Abelló/Merck) 8.9.1 Grazax/Grastek: Sales Forecast 2014-2024 8.10 Oralair (Grass pollen allergen extract, Stallergenes/Greer) 8.10.1 Oralair: Sales Forecast 2014-2024 8.11 Ragwitek (Short ragweed pollen allergen extract, Merck) 8.11.1 Ragwitek: Sales Forecast 2014-2024 9. Leading Companies in the Allergic Rhinitis Drugs Market 9. Leading Companies in the Allergic Rhinitis Drugs Market in 2014 9.1 Allergic Rhinitis Drugs: Merck & Co. Leads in a Fragmented Market 9.2 ALK-Abelló 9.2.1 ALK-Abelló: Allergic Rhinitis Drugs 9.2.2 ALK-Abelló: Allergic Rhinitis Sales Forecast 2014-2024 9.2.3 ALK-Abelló: Products in Development 9.2.4 ALK-Abelló: Recent Developments 9.2.4.1 ALK Collaborates with EddingPharm to Boost China Sales 9.2.4.2 Jext Product Recall 9.3 GSK 9.3.1 GSK: Allergic Rhinitis Drugs www.visiongain.com
  • Contents 9.3.2 GSK: Allergic Rhinitis Sales Forecast 2014-2024 9.3.3 GSK: Products in Development 9.3.4 GSK: Recent Developments 9.3.4.1 GSK Divestment of OTC Products 9.3.4.2 GSK Asset Swap with Novartis to Restructure Consumer Health 9.4 Johnson & Johnson 9.4.1 Johnson & Johnson: Allergic Rhinitis Drugs 9.4.2 Johnson & Johnson: Allergic Rhinitis Sales Forecast 2014-2024 9.4.3 Johnson & Johnson: Recent Developments 9.4.3.1 Launch of Zyrtec Dissolve Tabs 9.4.3.2 Manufacturing Recalls at McNeil Consumer Healthcare 9.5 Kyowa Hakko Kirin 9.5.1 Kyowa Hakko Kirin: Allergic Rhinitis Drugs 9.5.2 Kyowa Hakko Kirin: Allergic Rhinitis Sales Forecast 2014-2024 9.6 Merck & Co. 9.6.1 Merck: Allergic Rhinitis Drugs 9.6.2 Merck: Allergic Rhinitis Sales Forecast 2014-2024 9.6.3 Merck: Products in Development 9.6.4 Merck: Recent Developments 9.6.4.1 Bayer Acquires Merck’s Consumer Health Business 9.6.4.2 FDA Rejects Singulair OTC Switch 9.7 Sanofi 9.7.1 Sanofi: Allergic Rhinitis Drugs 9.7.2 Sanofi: Allergic Rhinitis Sales Forecast 2014-2024 www.visiongain.com
  • Contents 9.8 Stallergenes 9.8.1 Stallergenes: Allergic Rhinitis Drugs 9.8.2 Stallergenes: Allergic Rhinitis Sales Forecast 2014-2024 9.8.3 Stallergenes: Products in Development 9.8.4 Stallergenes: Recent Developments 9.8.4.1 Stallergenes Acquires Argentinean Company Alergo Pharma 9.8.4.2 Greer launches Oralair in the US 9.9 UCB 9.9.1 UCB: Allergic Rhinitis Drugs 9.9.2 UCB: Allergic Rhinitis Sales Forecast 2014-2024 9.10 Other Leading Companies 10. Allergic Rhinitis Pipeline Analysis 2014-2024 10. Allergic Rhinitis Drugs Pipeline Analysis 2014-2024 10.1 Trends and Developments in the Allergic Rhinitis Pipeline 10.2 The Oral Antihistamine Pipeline 2014 10.2.1 Talion (bepotastine, Mitsubishi Tanabe) 10.2.2 ZPL-3893787 (histamine H4R antagonist, Ziarco Pharma) 10.2.3 ZPL-868087 (oral histamine H3R antagonist, Ziarco Pharma) 10.3 The Intranasal Corticosteroids Pipeline 2014 10.3.1 APC-3000 (HFA inhaled corticosteroid, Adamis Pharmaceuticals) 10.3.2 S0597 (topical glucocorticoid, Sun Pharma) 10.3.3 TBS-6 (Trimel Pharmaceuticals) 10.4 The Immunotherapy Pipeline 2014 10.4.1 Actair (house dust mite SLIT, Stallergenes/Shionogi) www.visiongain.com
  • Contents 10.4.2 AllerT (subcutaneous birch pollen immunotherapy, Anergis) 10.4.3 Cat-SPIRE and other -SPIRE Therapies (synthetic peptide immunoregulatory epitopes, Circassia) 10.4.4 Depigoid Birch 5000 (birch pollen allergen extract, Leti Pharma) 10.4.5 House Dust Mite SLIT-Tablet (MK-8237, ALK-Abelló/Merck/Torii) 10.4.6 Pollinex Quattro (subcutaneous immunotherapies, Allergy Therapeutics) 10.4.7 gp-ASIT+ (grass pollen allergen fragments, Biotech Tools) 10.4.8 Betula verrucosa (Bet v) 1 allergen (Stallergenes) 10.5 The Pipeline for Other Allergic Rhinitis Drugs 2014 10.5.1 eN-Lac (Lactobacillus paracasei GMNL-32, GenMont Biotech) 10.5.2 S-555739 (prostaglandin D2 receptor antagonist, Shionogi) 10.5.3 DSP-3025/AZD-8848 (toll-like receptor 7 agonist, Dainippon Sumitomo/AstraZeneca) 10.5.4 GSK2245035 (toll-like receptor 7 agonist, GSK) 10.5.5 HP-3060 (transdermal long-acting tape, Hisamitsu) 10.5.6 MRX-4 (anti-inflammatory agent, Celsus Therapeutics) 10.5.7 OC459 (Oxagen/Atopix Therapeutics/Eleventa) 10.5.8 ONO-4053 (prostaglandin D2 receptor antagonist, Ono Pharmaceutical) 10.5.9 WF10 (tetrachlorodecaoxygen chlorite matrix, Nuvo Research) 10.5.10 RPL554 (PDE-3/PDE-4 antagonist, Verona Pharma) 10.5.11 VTX-1463 (toll-like receptor 8 agonist, VentiRx) 11. Qualitative Analysis of the Allergic Rhinitis Drugs Market 2014-2024 11. Qualitative Analysis of the Allergic Rhinitis Drugs Market 2014- 2024 11.1 SWOT Analysis of the Allergic Rhinitis Drugs Market www.visiongain.com
  • Contents 11.2 Strengths 11.2.1 High Unmet Clinical Need 11.2.2 Established Role of Allergic Rhinitis Drugs in Treatment 11.2.3 High Profile Disease Encouraging Improving Healthcare Provision 11.2.4 Increasing Consumer Demand 11.3 Weaknesses 11.3.1 Increasing Generic Penetration 11.3.2 Patient Dissatisfaction with Intranasal Corticosteroids 11.3.3 Limited Allergic Rhinitis Drugs Pipeline 11.4 Opportunities 11.4.1 The Rise of Immunotherapy 11.4.2 Higher Growth in Emerging Markets 11.4.3 Combination Drug Products 11.4.4 Rx-to-OTC Switching 11.5 Threats 11.5.1 Patent Expiry 11.5.2 Cost-Containment 11.5.3 Rising API and Manufacturing Costs 11.6 Porter’s Five Forces Analysis of the Allergic Rhinitis Drugs Market 11.6.1 Rivalry Among Competitors [High] 11.6.2 Threat of New Entrants [Low] 11.6.3 Power of Suppliers [Low] 11.6.4 Power of Buyers [Medium] 11.6.5 Threat of Substitutes [Low] www.visiongain.com
  • Contents 12. Research Interviews 12. Research Interviews 12.1 Interview with Maureen Jenkins, Director of Clinical Services for Allergy UK, Sidcup, Kent, UK 12.1.1 Allergic Rhinitis in the UK 12.1.2 Allergic Rhinitis Treatments 12.1.3 Opportunities for Manufacturers 12.2 Interview with Kimihiro Okubo, Chairman and Professor, Department of Otolaryngology, Nippon Medical School, Tokyo, Japan 12.2.1 Allergic Rhinitis in Japan 12.3 Interview with Jonathan Bernstein, Chairman and Professor, Department of Internal Medicine, University of Cincinnati, Ohio, US 12.3.1 Allergic Rhinitis in the US 12.3.2 Nasacort AQ and OTC Nasal Sprays 12.3.3 Dymista and Combination Therapies 12.3.4 Trends and Developments in Allergic Rhinitis 12.4 Interview with Tonya Winders, President and CEO, Allergy & Asthma Network Mothers of Asthmatics, Virginia, US 12.4.1 Allergic Rhinitis in the US 12.4.2 Allergic Rhinitis Treatments 12.4.3 US Healthcare Reform and Intranasal Drugs 12.5 Interview with Allergy Medical UK, Weybridge, UK 12.5.1 Allergic Rhinitis Treatments www.visiongain.com
  • Contents 13. Conclusions 13. Conclusions 13.1 Allergic Rhinitis Drugs: A Mature Market 13.2 The World Allergic Rhinitis Market in 2013 13.2.1 Current Leading Allergic Rhinitis Segments 13.2.2 Leading Allergic Rhinitis Products 13.2.3 Leading Allergic Rhinitis Drugs Companies 13.2.4 Leading National Markets 13.3 World Allergic Rhinitis Drugs Market Forecast 2014-2024 13.4 Allergic Rhinitis Late-Stage Pipeline 2014 13.5 The Future of the Allergic Rhinitis Drugs Market? www.visiongain.com
  • Allergic Rhinitis Drugs Market Forecast 2014-2024: Future Prospects for Companies in Antihistamines, Corticosteroids, Immunotherapy & Vaccines ISAAC epidemiological study of allergic rhinitis, Argentina, Brazil and Mexico had allergic rhinitis prevalences in 13-14 year olds (around 2002-2003) of 16.9%, 15.8% and 7.1% respectively. Another epidemiological study called Allergies in Latin America was conducted in February-April 2008 and reported that 67% of allergic rhinitis sufferers were using medication for their condition. 24% reported using a prescription nasal spray in the past four weeks while 42% also reported using OTC medication. Prescription nasal spray use was higher in Mexico (26%) and Argentina (21%) than in Brazil (19%). The opposite pattern was seen in terms of patients not being treated at all, with 43% not being treated in Brazil compared to 34% in Argentina and 28% in Mexico. Other countries with higher use of prescription nasal sprays were Venezuela (49%), Colombia (33%) and Chile (27%). The use of prescription nasal sprays was influenced by effectiveness, medical opinion, patient choice, side-effects and cost. These findings suggest that there is further room for expansion in the Brazilian and Mexican markets. 4.9.1 Brazilian Allergic Rhinitis Drugs Market Forecast 2014-2024 Table 4.15 and Figure 4.16 show visiongain’s forecast for the Brazilian allergic rhinitis drugs market over 2013-2024. Visiongain estimates that in 2013, the Brazilian allergic rhinitis drugs market reached $202m, representing 1.8% of the world market. In 2014 the Brazilian market will increase to $227m, up 12.3% on 2013. High growth in this market is expected as the demand for allergic rhinitis drugs increases. Expansion of healthcare provision in Brazil and strong economic growth will drive demand. Visiongain predicts that the Brazilian market will grow with a CAGR of 12.4% over 2013- 2018 to reach $363m in 2018. The Brazilian market will grow at a CAGR of 11.7% over 2018-2024 to reach $705m in 2024, representing an overall CAGR of 12.0% over 2013-2024. Table 4.15 Brazilian Allergic Rhinitis Drugs Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2013-2024 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 Brazil ($m) 202 227 255 289 323 363 409 466 526 589 655 705 Annual Growth Rate (%) 12.3 12.1 13.3 12.0 12.2 12.8 13.9 12.9 11.9 11.1 7.7 CAGR (%, 2013-2018 and 2018-2024) 12.4 11.7 CAGR (%, 2013-2024) 12.0 Source: visiongain 2014 www.visiongain.com Page 99
  • Allergic Rhinitis Drugs Market Forecast 2014-2024: Future Prospects for Companies in Antihistamines, Corticosteroids, Immunotherapy & Vaccines Table 6.18 and Figure 6.19 show visiongain’s estimates of Nasacort sales by volume over 2013- 2024. Table 6.18 Sanofi: Nasacort Sales Forecast by Volume: Sprays (million), AGR (%), CAGR (%), 2013-2024 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 Nasacort (million sprays) 2.1 6.3 8.9 11.5 13.8 12.7 12.1 11.7 11.6 12.1 12.6 13.1 Annual Growth Rate (%) 206.6 40.0 30.0 20.0 -8.0 -5.0 -3.0 -1.0 4.0 4.0 4.0 CAGR (%, 2013-2018 and 2018-2024) 43.9 0.4 CAGR (%, 2013-2024) 18.3 Source: visiongain 2014 Figure 6.19 Sanofi: Nasacort Sales Forecast by Volume: Sprays (million), AGR (%), 2013-2024 16.0 14.0 12.0 10.0 8.0 6.0 4.0 2.0 0.0 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 Volume (million sprays) Source: visiongain 2014 6.14 QNasl (beclometasone, Teva) 250.0 200.0 150.0 100.0 50.0 0.0 -50.0 AGR (%) Year Volume (million sprays) AGR (%) QNasl (beclometasone dipropionate, Teva) is a new formulation of beclometasone approved by the FDA in 2012. It is described as a “dry” nasal aerosol with a HFA propellant, as opposed to aqueous nasal sprays, and is the first such dry spray to reach the US market for allergic rhinitis. There is an unmet need for these types of spray due to the inconvenience of aqueous sprays: in 2010 the National Allergy Survey Assessing Limitations (NASAL) survey found that 1 in 5 patients www.visiongain.com Page 151
  • Allergic Rhinitis Drugs Market Forecast 2014-2024: Future Prospects for Companies in Antihistamines, Corticosteroids, Immunotherapy & Vaccines 7.8.1 Patanase: Sales Forecast 2014-2024 Visiongain estimates that in 2013, Patanase revenues reached $41m, little changed from 2012 revenues of $40m. Sales will grow 3.3% to $43m in 2014. Visiongain believes that growth will be slow during the forecast period, based on historical sales trends, and will reflect increasing demand for allergic rhinitis drugs offset by the fact that many alternatives are available, including generic azelastine. Visiongain predicts that Patanase revenues will grow with a CAGR of 3.9% over 2013- 2018 to reach $50m in 2018. Due to patent expiration in 2023 and falling revenues thereafter, Patanase revenues will decline at a CAGR of -4.4% over 2018-2024 to reach $38m in 2024, representing an overall CAGR of -0.7% over 2013-2024. Table 7.5 and Figure 7.7 show visiongain’s estimates of Patanase revenues over 2013-2024. Table 7.5 Novartis: Patanase Revenue ($m), AGR (%), CAGR (%), 2013-2024 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 Patanase ($m) 41 43 44 46 48 50 52 55 57 60 63 38 Annual Growth Rate (%) 3.3 3.7 4.0 4.2 4.4 4.6 4.8 5.0 5.1 5.1 -40.0 CAGR (%, 2013-2018 and 2018-2024) 3.9 -4.4 CAGR (%, 2013-2024) -0.7 Source: visiongain 2014 Figure 7.7 Novartis: Patanase Revenue ($m), AGR (%), 2013-2024 10.0 5.0 0.0 -5.0 -10.0 -15.0 -20.0 -25.0 -30.0 -35.0 -40.0 -45.0 70 60 50 40 30 20 10 0 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 AGR (%) Sales ($m) Year Sales ($m) AGR (%) Source: visiongain 2014 www.visiongain.com Page 181
  • Allergic Rhinitis Drugs Market Forecast 2014-2024: Future Prospects for Companies in Antihistamines, Corticosteroids, Immunotherapy & Vaccines Astepro 0.15%. They do work. In terms of compliance one spray versus two has advantages. Currently Dymista has a unique market space. 12.3.4 Trends and Developments in Allergic Rhinitis visiongain: Are there any other trends or developments in the intranasal allergic rhinitis drugs market? Jonathan Bernstein: QNasl, the HFA [hydrofluoroalkane] aerosol, has a new mode of delivery. In terms of novel compounds there are things in early stages of development that are being looked at but they haven’t generated data in significant patient populations as of yet. Other novel agents include intranasal CO2 and intranasal capsaicin which is over the counter and has effects on reducing congestion. For allergic rhinitis, sublingual immunotherapies have been looked at. There aren’t many novel nasal spray treatments under development at the moment. 12.4 Interview with Tonya Winders, President and CEO, Allergy & Asthma Network Mothers of Asthmatics, Virginia, US In March 2014 visiongain interviewed Tonya Winders, President and CEO of the Allergy and Asthma Network Mothers of Asthmatics (AANMA). AANMA is the leading nonprofit family health organisation in the US focusing on asthma, allergies and related conditions. We appreciate Tonya Winders’ time and opinions. 12.4.1 Allergic Rhinitis in the US visiongain: Can you tell me a little bit about the work that AANMA is doing in the area of allergic rhinitis? Tonya Winders: Allergy & Asthma Network Mothers of Asthmatics was founded in 1985 to "end the needless death and suffering due to asthma, allergies and related conditions through outreach, education and advocacy." The network is comprised of patients, caregivers and healthcare professionals dedicated to this mission. We provide training and educational materials for allergic rhinitis to millions of patients and caregivers each year. Many people believe allergic rhinitis is just “hay fever” or a mild nuisance to sufferers. In reality, it has a dramatic impact on a person’s quality of life including missed days at work and school or “presenteeism” – showing up but not being as productive as normal. The high direct and indirect www.visiongain.com Page 261