VITILIGO: Primitive acquired pigmentation disorder with focal depigmentation of the skin;
Characterized by well circumscribed milky white cutaneous/mucous macules;
Patches arise as a consequence of destruction and/or functional inactivation of melanocytes underlying a complex syndrome;
Acquired (only in few cases congenital), often familial (23% of the cases).
84% of dermatologists in The Netherlands are reluctant to start any active treatment in vitiligo; 82% in the Mediterranean area either prescribe placebos or treatments of cosmetic relevance only
Depigmentation ( Monobenzyl ether of hydroquinone, Q-switched ruby laser)
Repigmentation (corticosteroids, psoralen photochemotherapy, UVB phototherapy