Malaria Case Study

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Malaria & Case Study

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  • The most recognizable symptom of malaria is a very high fever, accompanied by fatigue, shakes, chills, and nausea. If treatment is sought with the first 24 hours after symptoms appear, malaria can more successfully be treated. When the symptoms progress– or when a case is particularly severe– malaria can often lead to death. The strain of malaria found most commonly in sub-Saharan Africa (plasmodium falciparum) is the most deadly. Malaria is a killer disease.
  • Malaria Case Study

    1. 1.  Malaria is an infectious disease, which is caused by protozoan parasites of genus plasmodium. Causative Organism :  Plasmodium falciparum  Plasmodium vivax  Plasmodium ovale  Plasmodium malariae
    2. 2. The Symptoms of Malaria Severe malaria • Seizures • Respiratory distress • Anemia • Organ failure • Coma • Death
    3. 3.  Microscopic examination of blood  Antigen detection test  Patients history & clinical observation
    4. 4.  4-Aminoquinolines— Chloroquine, Amodiaquine  Aryl-amino alcohols— Quinine, Mefloquine, Halofantrine  8-Aminoquinolines—Primaquine  Antifolate— Sulfadoxine, Proguanil, Pyrimethamine  Antibiotics—Tetracycline  Qinghaosu—Artemisinin (derived from leeches)  New drugs— Atovaquona, Pyronaridine, Benflumetol
    5. 5.  Mosquito nets  Keep your surroundings clean  Mosquito repellants  Vaccines for malaria are underdevelopment
    6. 6. Case Study
    7. 7.  Name – Mr. X  Age – 26 yrs  Gender – Male  Date of admission – 06/10/12  Date of discharge – 10/10/12
    8. 8. Chief complaints C/O fever, vomiting, back pain, fatigue, head ache X 3days. History of present illness H/O back pain ,headache. Past Medical History N/K/C/O DM, HTN, BA, Personal History Non-alcoholic, Non-smoker.
    9. 9. Physical Examination  Patient is conscious oriented  Temp- 104 F Pulse- 90/min  Bp- 130/90 mm/Hg RR- 20beats/min Systemic examination CVS- S1S2+ CNS- NFND RS- NVBS P/A- Soft
    10. 10. Data's Observed Value Normal Value Hb 12.6 gm/dl(↓) 14-18 RBC 4.4million/cubic mm(↓) 4.2-5.6 ESR(1 Hour) 25mm/hr(↑) 15-20 Platelet 110cubic mm (↓) 140-450 Pot 3.1meq/l (↓) 3.5-5.5 Bili (T) 1.8 mg/dl(↑) 0.2-1.4 Bili (D) 1.5mg/dl (↑) 0.0-0.4 Bili (ID) 0.3mm/dl Total-Direct
    11. 11. OTHER TEST’S  Dengue test – Negative  Polymerase chain reaction – Positive  MP QBC – Positive (P.vivax) Diagnosis Malaria
    12. 12. Drugs Dose R.O.A Frequency Duration IV Fluids 2 Days Cap. Doxycycline 100mg P/O BD X 5 Days Tab. Dolo 650mg P/O TDS X 1 Day Tab. Larigo 600mg P/O OD X 5 Days Inj. Emeset 4 mg I.V STAT X 2 Days
    13. 13. Doxycycline decrease the effect of amoxicilline by pharmacodynamic antagonism- Use alternatively Discharge Advice: Tab. Larigo (600mg) OD for 14 days Tab. Dolo (650mg) STAT Cap. Doxycycline (100mg) BD for 7 Days Review after 14 Days
    14. 14.  Take adequate rest  Drink plenty of clean water.  MB QBC Test recommended after 14 days

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