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Pharma 1st midterm
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Pharmacology

Pharmacology
Third Year

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Pharma 1st midterm Document Transcript

  • 1. Pharmacology: First major Exam – dental - 2013 Q-1: Define pharmacokinetics of drug: …………………………………………………………………………………………………………………………………… Q-2: Define bioavailability: …………………………………………………………………………………………………………………………………… Q-3: Write the following: a. Two advantages of intravenous of drug administration: 1. ………………………………………………………………………………… 2. ………………………………………………………………………………… b. Two factors that may affect drug absorption: 1. ……………………………………………………………………………… 2. ……………………………………………………………………………… Q-4: Mention two of the factors affecting renal excretion: 1. ………………………………………………. 2. ………………………………………………. Q-5: Define the following: a. Agonist: ……………………………………………………………………………………………………………………….. b. Drug tolerance: ……………………………………………………………………………………………………………………….. Q-6: Mention two unpredictable drug adverse effects: 1. ………………………………………………………………………….. 2. ………………………………………………………………………….. Q-7: Mention two drugs causing cytotoxic reaction and mention their cytotoxic effects: 1. Drug:………………… ……… Cytotoxic reaction:…………………………….………………. 2. Drug:………………… ……… Cytotoxic reaction:…………………………….……………….
  • 2. Q-8: Name two type of cholinergic receptors: 1. …………………………………………………………………. 2. …………………………………………………………………. Q-9: Write one therapeutic use for each one of the following cholinergics: a. Pilocarpine:………………………………………… b. Neostigamine:…………………………………………… Q-10: Mention two adverse effects of anti-cholinergics (e.g. Atropin) 1. …………………………………………………………… 2. …………………………………………………………… Q-11: Mention one action of anti-cholinergics on the following: a. GIT:………………………………………………………………………………… b. Eye: ……………………………………………………………………………….. Q-12: Write two actions of selective 2 agonists (e.g. salbutamol) 1. ……………………………………………………… 2. ……………………………………………………… Q-13: Mention two adverse effects of adrenaline: 1. ………………………………………………………….. 2. …………………………………………………………… Q-14: Name the following: a. One selective 1 agonists:………………………………………………… b. One selective 1 agonists:………………………………………………… Q-15: Name two 1 blockers and their uses: 1. Name:………………………………………….,Use:………………………………..….……………….. 2. Name:………………………………………….,Use:………………………………..….……………….. Q-16: List four uses of blockers: 1. …………………………………………………………………… 2. ……………………………………………………………………
  • 3. 3. …………………………………………………………………… 4. …………………………………………………………………… Q-17: a. Write names of two cardioselective blockers: 1. …………………………………………………….. 2. ……………………………………………………… b. Write two adverse effects of blockers: 1. ……………………………………………………… 2. ………………………………………………………. Q-18: Give two important examples of benzodiazepines and their one clinical use of each: Q-19: a. Name the drug used to treat benzodiazepines overdose:………………………………. b. Write the mechanism of action of Zolpidem: ……………………………………………………………………………………………………………………….. Q-20: a. Write the action of histamine on the following 1. Bronchial smooth muscle:……………………………………………………. 2. Blood pressure:……………………………………………………………………. b. List two important uses of first generation antihistamines: 1. ……………………………………………………………………….. 2. ……………………………………………………………………….. Q-21: a. Give two examples of less/non sedating (2nd generation) antihistamines: 1. …………………………………………….. 2. ………………………………………………. b. Write two important adverse effects of 1st generation antihistamines: 1. …………………………………………………… 2. …………………………………………………….
  • 4. Q-22: a. Give two examples of antihypertensive drugs that act centrally: 1. …………………………………………………………. 2. …………………………………………………………. b. List two adverse effects of calcium channel blockers: 1. …………………………………………………………. 2. ………………………………………………………….. Q-23: Mention two important adverse effects and two contraindications of ACE- inhibitor: a. Adverse effects: 1. ……………………………………………………….. 2. ………………………………………………………… b. Contraindications: 1. ………………………………………………………… 2. …………………………………………………………. Q-24: Write two therapeutic uses of selective 1 agonists: 1. …………………………………………….. 2. ………………………………………………. Q-25: a. In the management of anaphylactic shock, write the action of adrenaline on the following: 1. 1 adrenergic receptors:………………………………………..…………… 2. 1 adrenergic receptors:………..………………………….………………… 3. 2 adrenergic receptors:………………………………………………………. b. Name one important positive inotropic drug used to treat cardiogenic shock:………………………………………………