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Cell Membrane Structure and Function
Cell Membrane ,[object Object],[object Object],[object Object],[object Object],[object Object]
Membrane Structure ,[object Object],[object Object],[object Object]
The Cell Membrane
Cell membranes What is their structure?
We don’t know currently There are a number of hypotheses and we will consider the one which is currently accepted........
Structure - The Cell Membrane ,[object Object],[object Object],[object Object],[object Object]
The fluid mosaic model Lipids arranged in bi-layer with proteins embedded or associated with them.
Phospholipid Molecule Model glycerol fatty acids (hydrophobic) – hate water phosphate (hydrophilic) – like water Draw This
Membrane Lipids form a Bi-layer Outside layer Inside Layer
The fluid mosaic model  ,[object Object],[object Object],[object Object],[object Object]
Membrane Function ,[object Object],[object Object],[object Object],[object Object]
The cell membrance is a complex 3d circular structure The cell membrane is a complex 3 d structure .
Structure   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The fluid mosaic model
 
Composition of the cell membrane   Phospholipids Peripheral Proteins DRAW THIS Integral Proteins Trans – membrane proteins Cell Membrane
Phospholipids ,[object Object],[object Object],[object Object],[object Object]
Cholesterol ,[object Object],[object Object],[object Object],[object Object]
Glycolipids ,[object Object],[object Object]
Proteins ,[object Object],[object Object],[object Object]
Glycoproteins ,[object Object],[object Object],[object Object],[object Object]
Proteins - Glycoproteins ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Functions of membranes within cells (organelle membranes) ,[object Object],[object Object],[object Object]
Transport across the cell membrane ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Active and Passive Transport Summary
What does the membrane do? ,[object Object],[object Object],[object Object]
Membrane Permeability ,[object Object],[object Object],[object Object],[object Object],[object Object]
Membrane Semi-permeability ,[object Object],[object Object],[object Object],[object Object],1 2
Its about concentration The concentration of the solution, with respect to other solutions is important Isotonic  --- when both solutions have the same  concentration of dissolved substances Hypertonic  --- a solution with a higher  concentration of dissolved substances Hypotonic --- a solution with a lower   concentration of dissolved substances
Animal cells Plant cells
Two types of transport Passive and Active
Passive Transport ,[object Object],[object Object],KNOW THIS
Passive Transport 3 types ,[object Object],[object Object],[object Object],KNOW THESE
Diffusion Diffusion is the  passive movement  of particles from a  high concentration of particles  to a  lower concentration  until they are spread out evenly Smell Particles  &  Air Particles Solution Smell Particles  diffused evenly into the  Air Particles
Diffusion ,[object Object],[object Object],[object Object]
 
Solutions ,[object Object],[object Object],[object Object]
Diffusion & Gas Exchange ,[object Object],[object Object]
Diffusion for Photosynthesis ,[object Object],[object Object],[object Object],Water + Carbon Dioxide -> Oxygen and Glucose  (& a little water)
Diffusion & Photosynthesis CO 2 O 2
Rate of Diffusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Facilitated Diffusion ,[object Object],[object Object],[object Object],[object Object]
Facilitated Diffusion Glucose Transport protein Concentration gradient
Transport Proteins ,[object Object],[object Object],[object Object],[object Object]
Glucose Cell membrane Transport protein Glucose binds to the transport protein The transport protein turns over and releases glucose onto the inside of the cell, along the concentration gradient Concentration gradient
Types of Protein Transporters:   Ion Channels ,[object Object],[object Object],[object Object],[object Object],[object Object]
Carrier molecule Cell membrane Transport protein The carrier molecule binds to the transport protein, which opens the pore allowing it to move through the cell membrane. The pore closes once the carrier is inside the cell. Concentration gradient It is possible to  stop the action  of transport protein with drugs which will  block the pore.
Osmosis ,[object Object],[object Object],Osmosis is the movement of water molecules from a high concentration of water to a low concentration of water through a partially-permeable membrane
Osmosis
Osmosis
Osmosis Experiment ,[object Object],[object Object],[object Object],Glass tube Level of sugar solution Weak sugar solution Visking Tubing with Strong Sugar solution
Osmosis and Cells - Notes ,[object Object],[object Object]
Class Activity: Correctly Label Weak Solution Strong Solution Solute  Molecule Water Molecule Partially Permeable Membrane Which way will the water flow???
Osmosis
Osmosis and Animal Cells haemolysis Hypotonic solution Hypertonic solution
Osmosis & Plant Cells Turgid Cell Plasmolysed Cell Hypotonic solution Hypertonic solution
Plasmolysis in Elodea Plasmolysis in Elodea:  http://www.mrphome.net/mrp/Membrane_Transport.html
Active Transport ,[object Object],[object Object]
Transport proteins  ,[object Object],[object Object],ATP = Adenosine Triphosphate
Salt ion Cell membrane Transport protein Ion binds to the transport protein The transport protein turns over and releases the ion onto the inside of the cell, against the concentration gradient Concentration gradient Energy is used
Moving many large molecules at once—Endocytosis  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pseudopodia extend to engulf food A food vacuole is formed Pinocytosis works the same, but with no food, only liquid How Endocytosis works
Moving many large molecules at once— Exocytosis ,[object Object]
How exocytosis works Vacuole containing particles is moved close to the cell membrane Fuses with the cell membrane to expel the particles ,[object Object],[object Object]
Exocytosis the finer detail
Bulk Transport
Ion Channels ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Sodium-Potassium Pump
Na-K Pump Model:  Part I ,[object Object],[object Object],[object Object],[object Object]
Na-K Active Pump:  Part II ,[object Object],[object Object],[object Object],[object Object]
Root Hair Cells and Active Transport ,[object Object],[object Object]
Active Transport and Villi ,[object Object],[object Object]
Villi and Glucose Uptake
Passive vs. Active Transport

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2.4 Cell Membrane And Transport

  • 1. Cell Membrane Structure and Function
  • 2.
  • 3.
  • 5. Cell membranes What is their structure?
  • 6. We don’t know currently There are a number of hypotheses and we will consider the one which is currently accepted........
  • 7.
  • 8. The fluid mosaic model Lipids arranged in bi-layer with proteins embedded or associated with them.
  • 9. Phospholipid Molecule Model glycerol fatty acids (hydrophobic) – hate water phosphate (hydrophilic) – like water Draw This
  • 10. Membrane Lipids form a Bi-layer Outside layer Inside Layer
  • 11.
  • 12.
  • 13. The cell membrance is a complex 3d circular structure The cell membrane is a complex 3 d structure .
  • 14.
  • 16.  
  • 17. Composition of the cell membrane Phospholipids Peripheral Proteins DRAW THIS Integral Proteins Trans – membrane proteins Cell Membrane
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26. Active and Passive Transport Summary
  • 27.
  • 28.
  • 29.
  • 30. Its about concentration The concentration of the solution, with respect to other solutions is important Isotonic --- when both solutions have the same concentration of dissolved substances Hypertonic --- a solution with a higher concentration of dissolved substances Hypotonic --- a solution with a lower concentration of dissolved substances
  • 32. Two types of transport Passive and Active
  • 33.
  • 34.
  • 35. Diffusion Diffusion is the passive movement of particles from a high concentration of particles to a lower concentration until they are spread out evenly Smell Particles & Air Particles Solution Smell Particles diffused evenly into the Air Particles
  • 36.
  • 37.  
  • 38.
  • 39.
  • 40.
  • 42.
  • 43.
  • 44. Facilitated Diffusion Glucose Transport protein Concentration gradient
  • 45.
  • 46. Glucose Cell membrane Transport protein Glucose binds to the transport protein The transport protein turns over and releases glucose onto the inside of the cell, along the concentration gradient Concentration gradient
  • 47.
  • 48. Carrier molecule Cell membrane Transport protein The carrier molecule binds to the transport protein, which opens the pore allowing it to move through the cell membrane. The pore closes once the carrier is inside the cell. Concentration gradient It is possible to stop the action of transport protein with drugs which will block the pore.
  • 49.
  • 52.
  • 53.
  • 54. Class Activity: Correctly Label Weak Solution Strong Solution Solute Molecule Water Molecule Partially Permeable Membrane Which way will the water flow???
  • 56. Osmosis and Animal Cells haemolysis Hypotonic solution Hypertonic solution
  • 57. Osmosis & Plant Cells Turgid Cell Plasmolysed Cell Hypotonic solution Hypertonic solution
  • 58. Plasmolysis in Elodea Plasmolysis in Elodea: http://www.mrphome.net/mrp/Membrane_Transport.html
  • 59.
  • 60.
  • 61. Salt ion Cell membrane Transport protein Ion binds to the transport protein The transport protein turns over and releases the ion onto the inside of the cell, against the concentration gradient Concentration gradient Energy is used
  • 62.
  • 63. Pseudopodia extend to engulf food A food vacuole is formed Pinocytosis works the same, but with no food, only liquid How Endocytosis works
  • 64.
  • 65.
  • 68.
  • 70.
  • 71.
  • 72.
  • 73.
  • 75. Passive vs. Active Transport

Editor's Notes

  1. Topic 2: Cells; Membranes
  2. We will cover gas exchange in more detail later in the course in Unit 4. Topic 2: Cells; Membranes
  3. Weak solution = Low solute & lots of water High water concentration = weaker solution Topic 2: Cells; Membranes