Smart specialisation strategies in the Basque Country

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This presentation describes the Basque Strategies for industrial diversification in knowledge intensive sectors, namely Bio, Nano and Energy sectors (BioBasque, NanoBasque and EnergiBasque)

This presentation describes the Basque Strategies for industrial diversification in knowledge intensive sectors, namely Bio, Nano and Energy sectors (BioBasque, NanoBasque and EnergiBasque)

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  • 2. Basque strategies for industrial diversification in knowledge intensive sectors… Knowledge generationBusiness development Sector dynamisation
  • 3. …knowledge generation in the Basque innovation System
  • 4. …sustained public inventement in knowledge generation Ppto. SubvenciónPROYECTO Subv. 2009 Subv. 2010 Subv. 2011 Subv. 2012 Subv. 2013 Aceptado TotalGENEDIS 3 1.428.324 1.394.358 1.394.358LINCE 853.609 797.987 407.891 390.096ENERGIGUNE09 5.999.164 5.568.374 2.738.755 1.363.552 1.466.067ENERGIGUNE10 4.535.447 4.234.072 1.373.868 1.433.601 1.426.603ENERGIGUNE11 1.921.659 1.830.366 144.911 783.928 901.527PROGRAMA CICs 6.724.590 6.724.590 1.015.127 1.972.463 1.000.500 2.736.500 21.462.793 20.549.747 5.556.131 5.099.979 4.045.079 4.947.031 901.527
  • 5. …sustained public inventement in knowledge generation Ppto. Subvención PROYECTO Subv. 2009 Subv. 2010 Subv. 2011 Subv. 2012 Aceptado Total MICAS 1.651.080 1.495.380 1.495.380 MICAS-CIC 477.352 454.513 191.168 263.345 MIVDIRA 2.058.699 1.986.533 737.983 605.251 643.299 MIBIO2 4.343.582 4.192.184 1.784.335 1.109.151 1.298.698 PREDETECT 165.835 157.401 157.401 Programa CICs 1.970.751 1.970.751 397.854 554.487 187.633 830.776 10.667.299 10.256.762 2.822.385 3.207.418 2.097.484 2.129.474 Ppto. SubvenciónPROYECTO Subv. 2009 Subv. 2010 Subv. 2011 Subv. 2012 Subv. 2013 Aceptado Totali-NANOGUNE 3.679.916 3.410.876 1.591.696 1.819.180i-NANOGUNE II 4.779.529 4.615.276 1.528.800 1.498.606 1.587.870NANOIKER 5.871.699 5.621.876 2.065.804 1.654.834 1.901.238NANOIKER11 2.352.372 2.257.955 338.209 939.136 980.610Programa CICs 8.762.125 8.762.125 1.901.250 2.500.875 1.780.000 2.580.000 25.445.641 24.668.108 5.021.746 7.884.465 5.360.913 5.420.374 980.610
  • 6. …sustained public inventement in knowledge generation Ppto. SubvenciónPROYECTO Subv. 2009 Subv. 2010 Subv. 2011 Subv. 2012 Subv. 2013 Aceptado TotalBIOMAGUNE07 343.123 340.434 340.434BIOMAGUNE08 1.881.066 1.751.332 1.000.382 750.950BIOMAGUNE09 7.081.634 6.897.890 4.284.453 1.207.305 1.406.132BIOMAGUNE10 5.980.842 5.610.139 3.046.771 1.328.571 1.234.797BIOMAGUNE11 3.371.872 3.077.505 289.626 1.420.714 1.367.165Programa CICs 11.661.657 11.661.657 2.188.750 1.775.633 4.500.000 3.197.274 30.320.194 29.338.957 7.814.019 6.780.659 7.524.329 5.852.785 1.367.165 Ppto. SubvenciónPROYECTO Subv. 2009 Subv. 2010 Subv. 2011 Subv. 2012 Subv. 2013 Aceptado TotalBIOGUNE07 36.000 36.000 36.000BIOGUNE08 3.637.674 3.454.616 1.667.485 1.787.131BIOGUNE09 6.841.903 6.466.442 3.487.961 1.232.218 1.746.263BIOGUNE10 5.884.207 5.531.115 2.056.884 1.754.005 1.720.226BIOGUNE11 3.618.035 3.340.400 95.070 1.583.521 1.661.809Programa CICs 10.920.975 10.920.975 2.528.155 2.327.120 3.636.000 2.429.700 30.938.794 29.749.548 7.719.601 7.403.353 7.231.338 5.733.447 1.661.809
  • 7. …business development: impact on sectorsETORGAI programme: 140 M€ of public investment for the support ofcollaborative strategic industrial R&D (2008-2011) have mobilised 560 M€ 7
  • 8. …sector dynamization: innovation support systemR&D supportEntrepreneurshipTechnology TransferVenture capitalInternationalisationTalent attraction
  • 9. nanoBasqueStrategy A vision of the future
  • 10. The nanoBasque Strategy The incorporation of nanosciences, micro and nanotechnologies as an strategic area of industrial diversification within the Basque science, technology and innovation policies have been done with a twofold objective:  To exploit the large potential for application of these technologies in practically all the Basque industrial sectors  To promote the creation of new technology based firms (NTBF) specifically born to develop their activity with applications based on these technologies. 10
  • 11. The nanoBasque StrategynanoBasque is based on anew relational model, inwhich companies need tocooperate more closelywith research centers anduniversities for reaching aquantitative and qualitativestep ahead, to competeglobally with new productsand processes of greatervalue… 11
  • 12. The nanoBasque Strategy nanoBASQUE Strategy is structured around: Lines of action: Strategic areas/ Key concepts:  Business development  materials  Knowledge generation  micro- nano- bio convergence  Sector dynamization  enabling tools and techniques  environment, health and safety 12
  • 13. Knowledge generation New relational model is needed to transfer the generated knowledge  90% of companies active in micro/nano require the collaboration of scientific and technological agents for carrying out their activities  59 agents- of the 103 collaborators referred by the companies- are members of the Basque Science, Technology and Innovation network, being essential for the area development  Research Centers and Universities tend to be the main collaborators of the active firms *  The difficult access to equipments has been * identified as a major barrier to the micro – * nano activity development * * It is evident the importance of the scientific and technological agents in supporting the technological development of micro and nanotechnologies 13
  • 14. Knowledge generation Key strategic area for knowledge generation Enabling tools and techniques  The continued training of our scientific and technological system in tools and techniques for the characterization, synthesis, analysis, design, modeling, and manufacturing is key to enable the introduction of micro and nano in our companies.  The relevance of instrumentation is behind the strong stimulus provided by the Basque Government and embodied in the construction of world class facilities: the microGUNE and nanoGUNE Cooperative Research Centers, as well as the specific programs for the development of scientific infrastructures. 14
  • 15. Knowledge generationKnowledge development strategic areas and agents in nanosciences and nanotechnologies FIVE STRATEGIC AREAS Nanomagnetism Nanostructured materials for construction Carbon nanostructures Polymeric materials Nanophotonic devices + 200 researchers 15
  • 16. Knowledge generation Knowledge development Strategic areas and Agents in Microtechnologies Coordinates the research activity of 70 researchers Cooperation between different entities THREE STRATEGIC AREAS Microsensors Microfluidics Micro/Nano engineering 16
  • 17. Business Development: Impact on sectors. Key strategic areas for business development: Impact on sectors Materials  Key factor for the Basque business competitiveness  The micro and nanotechnology incorporation may allow:  An increase in the technology intensity  A diversification into higher value products We are not starting from scratch:  Strong capabilities in the Basque scientific and technological agents  Tractor companies in key sectors able to put the products of the future on the market. 17
  • 18. Business Development: Impact on sectors. There are 67 firms involved in micro and/or nano, 19 starts up Sector Distribution The horizontal nature of micro and nanotechnologies is reflected in the identification of active companies in more than 15 industrial sectors The use of these technologies in the steel, automotive and energy sectors is of special relevance 18
  • 19. Business Development: Impact on sectors. Projects examples Development of Nanotechnology based products and processes for the NANO-4-CAR automotive sector Development of Nanoalloyed special steels, for products of very high performance. Its nano structural characteristics allow to eliminate intensive DISAUTO energy intermediate operations in the manufacturing process. NANOSEG Development of new nanotechnolgy based products for the energy, food and automotive sector. New products for nanosafety ASEGURA Increase the safety without compromising the vehicle weight and fuel systems, incorporating innovative polymer for passive and active safety
  • 20. Business Development: New sector generation Key strategic areas for Business development: new sector generation Micro-Nano-Bio Convergence The convergence of these areas offers in the health and quality of life sector a perfect opportunity to enhance the Basque Country skills and to create market applications through joint knowledge. 20
  • 21. Business Development: New sector generation There are 67 firms involved in micro and/or nano, 19 start-ups Sector distribution The new technology based firms in micro and nanotechnology are concentrated in the areas of health, pharmaceuticals and biotechnology. 21
  • 22. Business Development: New sector generation. Some examples microINR: Oral Anticoagulation Therapy (OAT) Point of care monitoring Polymer microspheres for different applications: clinic diagnosis reactives, particular colloidal models … Tisular engineering and cellular therapy, devoted to the development of NANOSEG products in regenerative and repair medicine Development and commercialization of new biosensors that can detect ASEGURA molecules of interest for the enology, agro food and bio- health sectors.
  • 23. “A vision of the future”nanoBasque AgencyAmaia 23
  • 24. BioBasque, the Basque BioRegion A new hub for life sciences
  • 25. General context for life sciences in BioBasque• Commitment with biosciences: a longterm vision and strategy• Answers to global forces in health and sustainability• Life sciences as a new avenue for growth (with diversification from traditional industries)• A pro-business government• Proven Regional Innovation System• Pioneers in clustering• Integrative approach: translational research• State-of-the-art facilities and Technology platforms• Specialist research and business partners: efficacious and efficient
  • 26. BioRegion evolution: STIMain changes since 2002Increase in scientific and Biokutxatechnological capacitiesReinforced processes ofcompany creation(bioincubator) andacceleration
  • 27. Research community, Science & Technology capacity Specialist fields, converging technologiesGenomics and genotyping, Chemistry, Biophysics,gene silencing, proteomics, Pharmacology, etc.metabolomics, cellularbiology & stem cells, etc. Bioethics Researchers organised in “Knowledge Communities”, Private-public cooperation, IPR framework &Biomaterials,biosurfaces, protection Engineering,nanobiotechnology electronics, materials, manufacturingNanoscience & technology,microtechnologies
  • 28. State-of-the-art facilities and technology platforms (I)• Structural Biology: stepwise build-up from local toglobal structure with increasing resolution and complexity NMR Integral Electronic solutions Microscopy X-ray
  • 29. State-of-the-art facilities and technology platforms (I) Drug discovery and development by NMR Initial HITS LEADSDrug Target Affinity mM µM CANDIDATES NMR Screening Affinity µM nM • Highly sensitive NMR Screening LENS Process & Drug • NMR-tailored CombiChem Drug-Like Properties Candidate Library of Building Blocks • NMR-guided Drug Design Medicinal • Specialised Chemistry Ligand Library from • in vitro / in vivo Combinatorial testing of drug-like Chemistry ligands • ADME profiling LENS = Lead structure Evolution by NMR & Simulation
  • 30. State-of-the-art facilities and technology platforms (II)• Molecular (preclinical) Imaging: singular unit to study living organisms in a non-invasive manner, and to improve drug discovery & development • Computerized tomography, CT • Magnetic Resonance Imaging, MRI • Cyclotron (11,7 Tesla) • Radiochemistry lab • Radiopharmaceutical lab • Nuclear Imaging: PET, SPECT • fMRI, MRS • Animal facility
  • 31. The Health System Biomedical Research Institutes BIOEF aim: promotion of innovation and research in the Basque Public Health System. Nodal biobank within the health system.7 main hospitals (4 university), Experimental Units, Databases andregisters: mental health, cancer; longitudinal studies, health survey,Clinical Trials Network (1 regional Management Office)
  • 32. Business evolution in the BioRegion Business scenario in 2001 Not a sector, just companies
  • 33. Business scenario in 2010 A biocluster A new company every 3 months Nucleus: does not include telemedicine companies, etc.
  • 34. Some products
  • 35. BioBasque Agency Maria
  • 36. …