SysFera-DS & the Décrypthon project

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Presentation of how SysFera-DS helps the Décrypthon project (the technological platform of the French Téléthon) to use geographically distributed clusters for genomics computations with a simple …

Presentation of how SysFera-DS helps the Décrypthon project (the technological platform of the French Téléthon) to use geographically distributed clusters for genomics computations with a simple click.

Originally presented at Supercomputing 11 in Seattle, WA, 14-17 Nov.

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  • 1. Décrypthon research on rare diseases powered by Inria and SysFera technologies
  • 2. Who are you guys?
  • 3. SysFera
    • 2001: Research project from the Graal team (Inria/ENS)
      • DIET: grid middleware
    • 2007: SysFera-DS used within the Décrypthon project
      • Used in production 24/7/365 since then
      • 4. Selected by IBM to replace Univa-UD
    • 2010: Creation of SysFera, INRIA spin-off
    • 5. 2011: A team of 12 (R&D: 4 engineers and 5 PhD )
      • Supported by two experts from INRIA and ENS
      • 6. SysFera-DS
  • 7. Helping cure muscular distrophy
      The Décrypthon Steering Commitee chose SysFera-DS starting on June 2007 for its qualities of robustness and modularity. It has been progressively implemented on the Décrypthon grid's ressources while ensuring a completely transparent and smooth transition for the users.
    Thierry Toursel Research Project Manager, AFM
  • 8. The Décrypthon Project
  • 9. Décrypthon Project history
    • 2001: Opération Décrypthon
      • Objective: mapping the human proteome (560,000 proteins)
      • 10. 75,000 internet users mobilized during 5 months
      • 11. 1,710 years of computation
    • 2005: Décrypthon Program
      • Foster research in the domains of interest for the AFM (the French association against myopathies), thanks to grid computing technologies
  • 12. 8 projects selected
    • MS2PH: from Structural Mutation to the Phenotypes of Human Pathologies
    • 13. Splicing deficiencies and genetic illnesses
    • 14. Help Cure Muscular Dystrophy
    • 15. SpikeOmatic: sorting action potentials
    • 16. GEE: expressing the genes' evolution
    • 17. Conformational sampling and docking
    • 18. From functional genomics to the muscle
    • 19. Transcriptional networks during myogenesis
  • 20. The Décrypthon Grid
  • 21. The Décrypthon grid
    • production grid
    • 22. using university computing centers
    • 23. sharing resources between local users and users of the Décrypthon grid
    • 24. access to resources
    • 25. multiple interfaces: command line, Univa-UD
    • 26. users are not computer scientists
    • 27. integration of applications
    • 28. dependence on batch schedulers
  • 29. The Solutions
  • 30. Web interface & distributed middleware
  • 31. User and admin interface
  • 32. One app - one page
  • 33. User rights management
  • 34. Statistics Number of results per hour Size of produced results per cluster
  • 35. SysFera-DS does it all
  • 36. SysFera-DS does it all
    • Simple access to complex infrastructures
    • 37. Advanced administration features
      • User management and access control
      • 38. Monitoring and reporting
    • Integration to existing environments
    • 39. Compatibility with many different resources
    • 40. Non-intrusive, non-exclusive
    • 41. Flexible, stable, reliable, performant
  • 42. New web interfaces
  • 43. New web interfaces
  • 44. The power of the community
  • 45. The power of the community
      SysFera-DS is open-source software... ...which means anyone can use it, share it, and contribute to it.
  • 46. The power of the community
      Yes, it means you, too! So feel free to give it a try and become part of the community! ...and more!
  • 47. Need more info? Ask the SysFera team.
      Visit us on Booth #4211 www.sysfera.com