MALE REPRODUCTIVE SYSTEMPeculiarities of stroma in testis- T.albuginea is covered by serosa- includes SM and EF- in lobules fenestrated capillaries are located- Intersticial cell – endocrine – produce TESTOSTERON- endocrine function is under the hypothalamo-pituatary system control (LH)- interstitial (Leidig) cells form groups near capllaries, have round N andoxyphilic cytoplasm- EM: smooth ER, mitochondriae with tubulo-vesicular crysts, lipid droplets,crystalloid.
MALE REPRODUCTIVE SYSTEMSEMINIFEROUS TULULES1. Convoluted2. 1-4 tubules in one lobule3. Wall is lined by epitheliospermatogenic layer (ESL)4. ESL includes supporting (Sertolli) cells + spermatogenic cells5. Surrounded by myoid cells.
MALE REPRODUCTIVE SYSTEMSertolly`s cells- Pyramidal shape- Processes are joined by tight junctions and subdivide ESL into 2 poles- Poles: basal and adluminal- make microenvironment for prermatogenic cells- Participate in formation of blood-testis barrier 1 2 3 4 5
MALE REPRODUCTIVE SYSTEMSPERMATOGENIC cells- Spermatogonia- Primary spermatocytes- Secondary spermatocytes- Spermatides- Spermatozoa 3 3 1 1 3 3 2 1 2 1 А Б А Б
MALE REPRODUCTIVE SYSTEMSPERMATOGENESIS includes:1. Proliferation (mitosis)2. Growth (prophase of 1st meiotic division)3. Maturation (1st and 2nd meiotic division)4. Formation (differentiation – spermiogenesis) 1 2 3 4 5 6
MALE REPRODUCTIVE SYSTEM Spermiogenesis includes changes of: 1. Shape 2. Size of Nucleus 3. Number of mitochondriae 4. Location of Golgi apparatus 3. Acrosome formation 4. Microtubules arrangement with tail formation 3 2 3 2 3 4 7 5 65 5 4 А Б 1 8