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Male reproductive system
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Male reproductive system

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  • 1. Male reproductive system
  • 2. MALE REPRODUCTIVE SYSTEMCLASSIFICATION FUNCTIONS• TESTIS •GENERATIVE• GONADAL TRACT •ENDOCRINE• ACCESSORY GLANDS• PENIS
  • 3. MALE REPRODUCTIVE SYSTEM TESTISType of structure – parenchymal lobulatedStroma – Connective tissue + smooth myocytes + elastic fibres - Capsule - tunica albuginea (DCT + serosa) - Mediastinum (DCT) - Interlobular septae (DCT) - Intralobular LCT with calillaries and intersticial (endocrine) cellsParenchyma – seminiferous tubules 6 5 1 1 7 2 2 4 3 8
  • 4. MALE REPRODUCTIVE SYSTEMPeculiarities of stroma in testis- T.albuginea is covered by serosa- includes SM and EF- in lobules fenestrated capillaries are located- Intersticial cell – endocrine – produce TESTOSTERON- endocrine function is under the hypothalamo-pituatary system control (LH)- interstitial (Leidig) cells form groups near capllaries, have round N andoxyphilic cytoplasm- EM: smooth ER, mitochondriae with tubulo-vesicular crysts, lipid droplets,crystalloid.
  • 5. MALE REPRODUCTIVE SYSTEMSEMINIFEROUS TULULES1. Convoluted2. 1-4 tubules in one lobule3. Wall is lined by epitheliospermatogenic layer (ESL)4. ESL includes supporting (Sertolli) cells + spermatogenic cells5. Surrounded by myoid cells.
  • 6. MALE REPRODUCTIVE SYSTEMSertolly`s cells- Pyramidal shape- Processes are joined by tight junctions and subdivide ESL into 2 poles- Poles: basal and adluminal- make microenvironment for prermatogenic cells- Participate in formation of blood-testis barrier 1 2 3 4 5
  • 7. MALE REPRODUCTIVE SYSTEMSPERMATOGENIC cells- Spermatogonia- Primary spermatocytes- Secondary spermatocytes- Spermatides- Spermatozoa 3 3 1 1 3 3 2 1 2 1 А Б А Б
  • 8. MALE REPRODUCTIVE SYSTEMSPERMATOGENESIS includes:1. Proliferation (mitosis)2. Growth (prophase of 1st meiotic division)3. Maturation (1st and 2nd meiotic division)4. Formation (differentiation – spermiogenesis) 1 2 3 4 5 6
  • 9. MALE REPRODUCTIVE SYSTEM Spermiogenesis includes changes of: 1. Shape 2. Size of Nucleus 3. Number of mitochondriae 4. Location of Golgi apparatus 3. Acrosome formation 4. Microtubules arrangement with tail formation 3 2 3 2 3 4 7 5 65 5 4 А Б 1 8
  • 10. MALE REPRODUCTIVE SYSTEMBlood testis barrier1. Capallaries wall (Ec+BM)2. Perivascular LCT + Mph3. Myoid cells (+BM)4. Sertolli`s cells + BM and TJ 10 9 8 4 5 6 2 4 7 1 1 3 2 2
  • 11. Гипоталамус Тестостерон Гипофиз ЛГ ФСГ Семявыносящие пути Тестостерон АСБ Клетки Лейдига СуспендоцитRegulation of testis
  • 12. MALE REPRODUCTIVE SYSTEMDIAGNOSTICS
  • 13. MALE REPRODUCTIVE SYSTEMGonadal tract1. Intragonadal2. Extragonadal
  • 14. MALE REPRODUCTIVE SYSTEMEpidydimis: Type of structure – hollow with layerel wall1. Head2. Body3. Tail Layers:Two types of tubuled 1. Mucosa (Ep + Lamica propria)- Ductuli efferentis 2. Muscularis (Smooth muscles)- Ductus epidydimis 3. Adventitia. 2 1 3 1 4 2 5
  • 15. Accessory glandsSeminal vesicles
  • 16. Accessory glands 1 2 2 4 156 5 4 3 6 6 3 Prostate