Pancreatitis

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Pancreaitis

Pancreaitis

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  • 1. Pancreatitis Sherry L. Knowles, RN, CCRN, CRNI Orlando Regional Medical Center Orlando Health Pancreatitis Can Be Fatal
  • 2. Anatomy & Physiology
    • The Pancreas secretes digestive enzymes into the duodenum via the pancreatic duct.
    • (Lipase, Amylase, Trypsin)
    • The Pancreas also secretes bicarbonate, water, and lytes into the duodenum.
    • The Pancreas produces and secretes insulin as needed.
  • 3. Definition of Pancreatitis
      • Inflammation of the pancreas associated with autodigestion
      • An autodigestive process resulting from premature activation of pancreatic enzymes.
      • May be acute or chronic
  • 4. Physiology of Pancreatitis
      • Inactive pancreatic enzymes are activated outside of the duodenum
      • The swelling pancreas causes fluids to shift into the retro peritoneum and bowel
      • Fluid shifts can cause severe hypovolemia and hypotension
  • 5. Causes of Pancreatitis
    • Alcoholism
    • Biliary Disease
    • Infections
    • Hyperparathyroidism
    • Hypertriglyceridemia
    • Hypercalcemia
    • Peptic Ulcer Disease
    • Cystic Fibrosis
    • Vascular Disease
    • Multiple Drugs
  • 6. Signs & Symptoms of Pancreatitis
    • Abdominal Pain
    • Nausea & Vomiting
    • Abdominal Distention
    • Jaundice
    • Malnutrition
    • Hematemesis
    • Grey Turner’s Sign
    • Cullen’s Sign
    • Elevated Amylase, Lipase, LDH,
    • AST, WBC’s BUN, and Glucose
  • 7. Complications of Pancreatitis
    • Hypocalcemia
    • Hypotension
    • Acute Tubular Necrosis
    • DIC
    • Obstructive Jaundice
    • Erosive Gastritis
    • Paralytic Ileus
    • Pseudocyst or Abscess
    • Bowel Infarction
    • Internal Bleeding
    • Fat Necrosis
    • Pleural Effusion
    • Pulmonary Infiltrates
    • Hypoxemia
    • Atelectasis
    • ARDS
    • Pericardial Effusion
    • Mediastinal Abscess
    • Hyperglycemia
    • Hypertriglyceridemia
    • Encephalopathy
  • 8. Treatment of Pancreatitis
    • Stabilization: Correct Fluid And Electrolyte Status
    • Respiratory Support (as needed)
    • Control Pain (Demerol)
    • NG Tube (NPO)
    • TPN (Restricted Diet)
    • Monitor For Complications
    • Monitor Blood Sugar
    • Drug Therapies (Somatostatin, Anticholinergics)
    • Watch For Signs Of Infection
    • Pray
  • 9. Pancreatitis Can Be Fatal THE END