World Tuberculosis Day 2013TB situation in 2011:Findings from the ECDC and WHO/EUROjoint TB surveillance reportECDC TB Tea...
TB notification rates in EU/EEA, 2011  In the EU/EEA, 72 334 TB cases were reported in 2011.  Notification rate 14.2 per 1...
TB notification rates in EU/EEA, 2007−2011Overall in the EU/EEA, notification rates have steadily declined.Figure 2: Trend...
Proportion of confirmed* TB cases in the EU/   EEA, 2011   Overall 61.3% (range 27.9 – 94.8%) of TB cases reported in   th...
TB notification rates in children <15 years  of age in EU/EEA, 2011  In 2011, 3 190 cases of TB in children were reported,...
Proportion of foreign origin among notified   TB cases in EU/EEA, 2011   In 2011, the overall proportion of TB cases of fo...
Proportion of notified extrapulmonary   TB cases in EU/EEA, 2011   In 2011, the overall proportion of extrapulmonary TB ca...
Extrapulmonary TB notification rates in                         EU/EEA, 2002−2011                         Extrapulmonary T...
Proportions of TB by site among all notifiedTB cases in EU/EEA, 2002−2011Percentage of extrapulmonary TB increased from 16...
Proportion of culture-confirmed new      pulmonary TB cases in EU/EEA, 2011      61% of new pulmonary TB cases were cultur...
Proportion of notified TB cases with multi-   drug resistance among all confirmed TB   cases in EU/EEA, 2011   In 2011, th...
Proportion of notified new TB cases with   multidrug resistance in EU/EEA, 2011   In 2011, the overall proportion of new T...
Notification rates of new cases withmultidrug resistant TB in EU/EEA, 2007−2011The notification rate of multidrug resistan...
Proportion of notified previously treated   TB cases with multidrug resistance in EU/   EEA, 2011   In 2011, the overall p...
Proportion of TB cases with extensive drug   resistance among MDR-TB cases with SLD   ST* reported in EU/EEA, 2011   In 20...
Proportion of HIV positive TB cases among   all TB cases with known HIV status in EU/   EEA, 2011   In 2011, the overall p...
Treatment success rate for new pulmonaryTB cases in EU/EEA*, 2010The treatment success rate for new culture-confirmed pulm...
Treatment success rate for newpulmonary TB cases by year of reportingin EU/EEA, 2006−2010The treatment success rate for ne...
Treatment success rate for previously  treated pulmonary TB cases in EU/EEA*,  2010  The treatment success rate for previo...
Treatment success rate for all notifiedpulmonary TB cases in EU/EEA*, 2010The treatment success rate for all confirmed pul...
Treatment success* rate for extra-pulmonary TB cases in EU/EEA**, 2010The treatment success rate for extrapulmonary TB cas...
Treatment success rate for notifiedmultidrug-resistant TB cases in EU/EEA*,2009The treatment success rate for all confirme...
Treatment outcome for multidrug-resistantTB cases notified in 2007−2009Treatment outcomes for multidrug-resistant TB cases...
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TB situation in 2011:Findings from the ECDC and WHO/EURO joint TB surveillance report

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TB situation in 2011:Findings from the ECDC and WHO/EURO joint TB surveillance report

  1. 1. World Tuberculosis Day 2013TB situation in 2011:Findings from the ECDC and WHO/EUROjoint TB surveillance reportECDC TB TeamEuropean Centre for Disease Prevention and ControlStockholm, 24 March 2013
  2. 2. TB notification rates in EU/EEA, 2011 In the EU/EEA, 72 334 TB cases were reported in 2011. Notification rate 14.2 per 100 000 population (range 2.8–89.7). Figure 1: Country-specific TB notification rates, 2011< 10 per 100 00010 to 19 per 100 00020 to 49 per 100 00050 to 99 per 100 000Not included or notreporting 2
  3. 3. TB notification rates in EU/EEA, 2007−2011Overall in the EU/EEA, notification rates have steadily declined.Figure 2: Trend in TB notification rate in the EU/EEA 2007−2011 20Notification rate per 100 000 population 16,8 16,5 15 15,8 14,9 14,2 10 5 2007 2008 2009 2010 2011 Year of reporting 3
  4. 4. Proportion of confirmed* TB cases in the EU/ EEA, 2011 Overall 61.3% (range 27.9 – 94.8%) of TB cases reported in the EU/EEA were laboratory-confirmed. Figure 3: Country-specific proportion of all confirmed TB cases in 2011< 60%60 to 69%70 to 79%≥ 80%Not included ornot reporting * Confirmed by culture or both a positive sputum microscopy result and Mycobacterium tuberculosis nucleic acid identified in nucleic acid amplification test. 4
  5. 5. TB notification rates in children <15 years of age in EU/EEA, 2011 In 2011, 3 190 cases of TB in children were reported, accounting for 4.4% of all notified TB cases (range 0 – 11.1%) in the EU/EEA. Figure 4: Country-specific childhood TB notification rates among child population (0–14 years), 2011 < 2 per100 000 child population2 to 3.9 per100 000 child population4 to 9.9 per100 000 child population≥ 10 per100 000 child populationNot included or notreporting 5
  6. 6. Proportion of foreign origin among notified TB cases in EU/EEA, 2011 In 2011, the overall proportion of TB cases of foreign origin in the EU/EEA was 25.8% (range 0.3 – 89.4%). Figure 5: Country-specific proportion of foreign origin cases among all notified TB cases, EU/EEA, 2011< 1%1 to 24%25 to 49%50 to 74%≥ 75%Not included ornot reporting 6
  7. 7. Proportion of notified extrapulmonary TB cases in EU/EEA, 2011 In 2011, the overall proportion of extrapulmonary TB cases in the EU/EEA was 22.3% (range 3.9 – 66.7%). Figure 6: Country-specific proportion of extrapulmonary TB of all notified TB cases, EU/EEA, 2011< 1%1 to 19%20 to 29%30 to 49%≥ 50%Not included ornot reporting 7
  8. 8. Extrapulmonary TB notification rates in EU/EEA, 2002−2011 Extrapulmonary TB notification rates have remained stable in the last 10 years. Figure 7: Trend in extrapulmonary TB notification rate in the EU/EEA, 2002−2011 5Notification rate per 100 000 population 4 3 3,4 3,4 3,5 3,4 3,5 3,4 3,3 3,2 3,3 3,2 2 1 0 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 Year of reporting 8
  9. 9. Proportions of TB by site among all notifiedTB cases in EU/EEA, 2002−2011Percentage of extrapulmonary TB increased from 16.4% in 2002 to 22.4% in 2011.Figure 8: Proportion of notified pulmonary andextrapulmonary TB cases in the EU/EEA, 2002−2011Number of cases100000 Pulmonary TB Extrapulmonary TB 90000 80000 70000 60000 50000 40000 30000 20000 10000 0 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 Year of reporting 9
  10. 10. Proportion of culture-confirmed new pulmonary TB cases in EU/EEA, 2011 61% of new pulmonary TB cases were culture-confirmed. The proportion varied widely across countries (range 33 – 98%). Figure 9: Proportion of new pulmonary TB cases confirmed by culture, 2011 100 90 80 70Percentage 60 50 40 30 20 10 0 10
  11. 11. Proportion of notified TB cases with multi- drug resistance among all confirmed TB cases in EU/EEA, 2011 In 2011, the overall proportion of TB cases with multi-drug resistance in the EU/EEA was 4.5% (range 0 – 29.8%). Figure 10: Country-specific proportion of multidrug resistance among all confirmed TB cases, EU/EEA, 2011< 1%1 to 1.9%2 to 4.9%5 to 9.9%≥ 10%Not included ornot reporting 11
  12. 12. Proportion of notified new TB cases with multidrug resistance in EU/EEA, 2011 In 2011, the overall proportion of new TB cases with multi- drug resistance in the EU/EEA was 2.4% (range 0 – 23.3%). Figure 11: Country-specific proportion of new TB cases with multidrug resistance, EU/EEA, 2011< 1%1 to 1.9%2 to 4.9%5 to 9.9%≥ 10%Not included ornot reporting 12
  13. 13. Notification rates of new cases withmultidrug resistant TB in EU/EEA, 2007−2011The notification rate of multidrug resistant TB have remained stable at around0.3 per 100 000 population.Figure 12: Trends in multidrug resistant TB notification rate in the EU/EEA,2007−2011 0,4 Notification rate per 100 000 population 0,3 0,33 0,35 0,33 0,30 0,30 0,2 0,1 0,0 2007 2008 2009 2010 2011 Year of reporting 13
  14. 14. Proportion of notified previously treated TB cases with multidrug resistance in EU/ EEA, 2011 In 2011, the overall proportion of previously treated TB cases with multidrug resistance in the EU/EEA was 16.8% (range 0 – 57.7%). Figure 13: Country-specific proportion of previously treated TB cases with multi-drug resistance, EU/EEA, 2011< 1%1 to 1.9%2 to 4.9%5 to 9.9%≥ 10%Not included ornot reporting 14
  15. 15. Proportion of TB cases with extensive drug resistance among MDR-TB cases with SLD ST* reported in EU/EEA, 2011 In 2011, the proportion of extensive drug resistant cases among cases with multidrug resistance in EU/EEA was 13.4% (range 0 – 40.0%). Figure 14: Country-specific proportion of extensively drug-resistant TB cases among TB cases with multi-drug resistance, EU/EEA, 2011< 1%1 to 4%5 to 9%10 to 19%≥ 20% orNot included orNot includednot reportingnot reporting *SLD ST – second line drug susceptibility testing result 15
  16. 16. Proportion of HIV positive TB cases among all TB cases with known HIV status in EU/ EEA, 2011 In 2011, the overall proportion of HIV positive TB cases among TB cases with known HIV status in EU/EEA was 4.7% (range 0 – 40%). Figure 15: Country-specific proportion of HIV positive TB cases among TB cases with known HIV status, EU/EEA, 2011< 1%1 to 1.9%2 to 4.9%5 to 9.9%≥ 10%Not included ornot reporting 16
  17. 17. Treatment success rate for new pulmonaryTB cases in EU/EEA*, 2010The treatment success rate for new culture-confirmed pulmonary TB cases notified in2010 was 76.8% (range: 0 – 91.4%).Figure 16: Treatment success rate for new culture-confirmedpulmonary TB cases notified in 2010 100Treatment success (%) 80 60 40 20 0* Five EU/EEA Member States did not report treatment outcome data. 17
  18. 18. Treatment success rate for newpulmonary TB cases by year of reportingin EU/EEA, 2006−2010The treatment success rate for new culture-confirmed pulmonary TB cases notifiedbetween 2006 and 2010 has slightly decreased from 79.5% in 2006 to 76.8% in 2010.Figure 17: Treatment success rate for new culture-confirmed pulmonaryTB cases notified in 2006−2010 100 80Treatment success (%) 79,5 79,2 79,5 78,9 76,8 60 40 20 0 2006 2007 2008 2009 2010 Year of reporting 18
  19. 19. Treatment success rate for previously treated pulmonary TB cases in EU/EEA*, 2010 The treatment success rate for previously treated culture-confirmed pulmonary TB cases notified in 2010 was 53.7% (range 31.4 – 85.7%). Figure 18: Treatment success rate for previously treated culture-confirmed pulmonary TB cases notified in 2010 100Treatment success (%) 80 60 40 20 0 * Iceland and Luxembourg reported zero previously treated TB cases in 2010. Seven EU/EEA Member States did not report stratified treatment outcome data 19
  20. 20. Treatment success rate for all notifiedpulmonary TB cases in EU/EEA*, 2010The treatment success rate for all confirmed pulmonary TB cases notifiedin 2010 was 74.3% (range 0 – 90.1%).Figure 19: Treatment success rate for all confirmed pulmonary TB cases notified in2010 100 80Treatment success (%) 60 40 20 0 * Five EU/EEA Member States did not report treatment outcome data 20
  21. 21. Treatment success* rate for extra-pulmonary TB cases in EU/EEA**, 2010The treatment success rate for extrapulmonary TB cases notified in 2010 was82.2% (range 21.1 – 100%).Figure 20: Treatment success rate for extrapulmonary TB cases notified in 2010 100 80Treatment success (%) 60 40 20 0* Treatment success of extrapulmonary TB consists of cases reported as completed full course of anti-tuberculosis treatment** Seven Member States did not report stratified treatment outcome data 21
  22. 22. Treatment success rate for notifiedmultidrug-resistant TB cases in EU/EEA*,2009The treatment success rate for all confirmed multidrug-resistant TB cases notified in2009 was 31.6% (range 0 – 84.6%).Figure 21: Treatment success rate for all confirmed multidrug-resistant TBcases notified in 2009 100 80Treatment success (%) 60 40 20 0* Malta reported zero MDR TB cases in 2009, 11 Member States did not report treatment outcome data 22
  23. 23. Treatment outcome for multidrug-resistantTB cases notified in 2007−2009Treatment outcomes for multidrug-resistant TB cases did not improve between the2007 and 2009 cohort, EU/EEA.Figure 22: Treatment outcome at 24 months for multidrug-resistant TB casesdiagnosed in 2009, compared with cases diagnosed in 2007 and 2008 35 cohort 2009 (18 countries) 30 cohort 2008 (20 countries) 25 cohort 2007 (15 countries)Percentage 20 15 10 5 0 Success Died Failed Defaulted Still on Transferred or treatment unknown 23
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